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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: Difference in mobilization of progenitor cells after myocardial infarction in smoking versus non-smoking patients: insights from the BONAMI trial

Figure 1

Correlations between CD45dimCD34 + KDR + cell number at baseline and change in LVEF (A), in myocardial viability improvement (B,C), in infarct size (D,E), in patients of the control group reassessed at three months follow-up. Black square: former smokers and non-smokers, white rhombus: active smokers at the time of AMI. Myocardial viability improvement was expressed as the number of non-viable segments at baseline that were viable at three months follow-up, measured by four-hour resting SPECT. No significant interaction was observed between cell number, smoking status and LVEF. Correlation between change in LVEF and cell number was significant after adjustment for smoking status (P = 0.05). Interaction between CD45dimCD34 + KDR + cell number, smoking status and myocardial viability improvement (measured as the increase in viable segment number) was significant (P = 0.02). Interaction between CD45dimCD34 + KDR + cell number, smoking status and infarct size was significant (P = 0.01). AMI, acute myocardial infarction; LVEF, left ventricular ejection fraction; SPECT, thallium-201-gated-single-photon-emission computed tomography.

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Stem Cell Research & Therapy

ISSN: 1757-6512