Figure 10

Immunohistochemical (IHC) staining for kidney expressions of anti-oxidative markers at 72 hours after the CLP procedure. A to D) Microscopic findings of IHC stain (200x) for glutathione reductase (GR)-positive cells (brown) in renal parenchyma of the four groups. Scale bars in the right lower corner represent 50 μm. E) * versus other groups with different symbols (*, †, ‡), P <0.0001. F to I) Microscopic findings of IHC stain (200x) for glutathione peroxidase (GPx)-positive cells (brown) in renal parenchyma of the four groups. Scale bars in the right lower corner represent 50 μm. J) * versus other groups with different symbols (*, †, ‡, ¶), P <0.0001. All statistical analyses using one-way ANOVA, followed by the Bonferroni multiple comparison post hoc test (n = 8). Symbols (*, †, ‡, §) indicate significance (at 0.05 level). SC ,sham control; CLP, cecal ligation and puncture; H-ADMSC, healthy adipose-derived mesenchymal stem cell; A-ADMSC, apoptotic adipose-derived mesenchymal stem cell. ANOVA, analysis of variance.