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Table 1 Blood pressure, hematologic and biochemical studies among the four groups

From: Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats

Variables

Group 1

Group 2

Group 3

Group 4

P-value

Systolic blood pressure (mmHg)

     

At 0 hour

125.8 ± 5.5

123.4 ± 4.7

119.5 ± 4.6

117.5 ± 4.2

0.647

At 72 hours

129.1 ± 7.6a

102.6 ± 5.6b

82.1 ± 5.8c

119. 1 ± 7.7a

<0.001

At 24 hours

     

Creatinine

0.51 ± 0.12

0.77 ± 0.15

0.74 ± 0.25

0.66 ± 0.14

0.051

WBC count

8.1 ± 2.0

4.9 ± 2.6

7.7 ± 2.5

6.8 ± 1.4

0.057

At 72 hours

     

Creatinine

0.5 ± 0.07a

0.78 ± 0.14b

0.83 ± 0.17b

0.61 ± 0.11a

<0.001

WBC count

7.7 ± 1.9a

12.6 ± 2.8b

9.2 ± 3.1c

9.5 ± 2.3c

0.016

Serum TNF-α level (ng/mL)

     

At 0 hour

1.92 ± 0.81

1.89 ± 1.04

2.13 ± 1.18

2.22 ± 1.40

0.887

At 24 hours

2.16 ± 1.46a

11.6 ± 2.72b

15.9 ± 5.4c

12.21 ± 5.81b

<0.001

At 72 hours

2.4 ± 1.58a

5.92 ± 1.92b

8.53 ± 8.56b

4.24 ± 1.27c

<0.001

  1. Data are expressed as means ± SD. Group 1, sham control; group 2, cecal ligation and puncture (CLP); group 3, CLP + healthy adipose-derived mesenchymal stem cell (H-ADMSC); group 4, CLP + adipose (A)-ADMSC. Symbols (a, b, c) indicate significant difference (at 0.05 level) by Bonferroni multiple-comparison post hoc test. WBC, white blood cells.