Skip to main content

Advertisement

Table 1 Blood pressure, hematologic and biochemical studies among the four groups

From: Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats

Variables Group 1 Group 2 Group 3 Group 4 P-value
Systolic blood pressure (mmHg)      
At 0 hour 125.8 ± 5.5 123.4 ± 4.7 119.5 ± 4.6 117.5 ± 4.2 0.647
At 72 hours 129.1 ± 7.6a 102.6 ± 5.6b 82.1 ± 5.8c 119. 1 ± 7.7a <0.001
At 24 hours      
Creatinine 0.51 ± 0.12 0.77 ± 0.15 0.74 ± 0.25 0.66 ± 0.14 0.051
WBC count 8.1 ± 2.0 4.9 ± 2.6 7.7 ± 2.5 6.8 ± 1.4 0.057
At 72 hours      
Creatinine 0.5 ± 0.07a 0.78 ± 0.14b 0.83 ± 0.17b 0.61 ± 0.11a <0.001
WBC count 7.7 ± 1.9a 12.6 ± 2.8b 9.2 ± 3.1c 9.5 ± 2.3c 0.016
Serum TNF-α level (ng/mL)      
At 0 hour 1.92 ± 0.81 1.89 ± 1.04 2.13 ± 1.18 2.22 ± 1.40 0.887
At 24 hours 2.16 ± 1.46a 11.6 ± 2.72b 15.9 ± 5.4c 12.21 ± 5.81b <0.001
At 72 hours 2.4 ± 1.58a 5.92 ± 1.92b 8.53 ± 8.56b 4.24 ± 1.27c <0.001
  1. Data are expressed as means ± SD. Group 1, sham control; group 2, cecal ligation and puncture (CLP); group 3, CLP + healthy adipose-derived mesenchymal stem cell (H-ADMSC); group 4, CLP + adipose (A)-ADMSC. Symbols (a, b, c) indicate significant difference (at 0.05 level) by Bonferroni multiple-comparison post hoc test. WBC, white blood cells.