Percentage wound closures as assessed using wound tracing. To determine if there was a difference in percentage wound closure, ANOVA was used. For the ANOVA analysis there was a significant difference between groups (P = 0.003). The error bars represent standard deviation. The number of wounds per group was eight (n = 8). To determine if there was a difference between individual groups, post hoc testing with Fisher’s test was used. The statistical results are reported as 95% confidence intervals (CI). * denotes a significant difference in wound closure ((95% CI (14.109, 32.242)). ** denotes a significant difference in wound closure ((95% CI (6.188, 24.321)). A significant difference is also present when comparing wound closure between CAC + collagen treated wounds and untreated wounds ((95% CI (4.743, 22.877)).