Skip to main content

Table 1 Summary of vertebrate haploid cells

From: Haploid embryonic stem cells serve as a new tool for mammalian genetic study

Cell type Origin Pluripotency Germline competence Dependent factors for self-renewal Genome stability Function as gametes
Fish phES cells Parthenogenetic haploid embryos Yes Yes bFGF and LIF Stable Yes
Mouse phES cells Parthenogenetic haploid embryos Yes Yes 2i and LIF Stable, with auto-diploidization Yes
Mouse ahES cells Androgenetic haploid embryos Yes Yes 2i and LIF Stable, with auto-diploidization Yes
Monkey phES cells Parthenogenetic haploid embryos Yes ND bFGF Stable, with auto-diploidization ND
Human near-haploid cells Tumors No No ND Unstable, with chromosome loss No
  1. ahES, androgenetic haploid embryonic stem; bFGF, basic fibroblast growth factor; LIF, leukemia inhibitory factor; ND, not determined; phES, parthenogenetic haploid embryonic stem.