Figure 5

Pulmonary edema is prevented in animals instilled with adult stem cells after endotoxin injury. (A) Tissue samples were collected right before and after endotoxin infusion and at the end of the experiment from both lungs. Water content was measured by calculating the weight before and after the tissue was dehydrated, and the ratio was then calculated. Each sample consisted of five replicates. The control group is represented by open circles and the stem cell group by black circles. Total cell number and neutrophil concentration in bronchoalveolar lavage (BAL) tend to be higher in control animals than in those treated with stem cells. Left (B,D) and right (C,E) lungs. The total cell count in BAL (B,C) and the percent of neutrophils (D,E) are shown for time points before (Bf) and after endotoxin infusion and at the end of the study. The control group (no treatment) is represented with open circles and the experimental group (receiving stem cells) is shown in black circles.