Figure 5

Photomicrographs showing expression of ionized calcium-binding adapter molecule-1 (Iba-1) in ipsilateral hemisphere of cell-transplanted and PBS-group animals. A marked decrease in activated macrophage/microglial Iba-1-positive cells was seen in all three cell-group animals compared with the PBS group. The Iba-1-positive cells seen in cell-group animals had both ramified and amoeboidal morphology compared with more-compact amoeboidal morphology seen in the PBS group. Decrease in expression of Iba-1 was more prominent in ipsi-striatum (B) than in ipsi-cortex (A). Scale bar = 100 μm.