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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: RETRACTED ARTICLE: Umbilical cord tissue-derived mesenchymal stem cells induce apoptosis in PC-3 prostate cancer cells through activation of JNK and downregulation of PI3K/AKT signaling

Figure 2

The inhibitory effect of hUCMSCs on prostate cancer cell growth in direct or indirect coculture condition. PC-3 cells (5 × 104) were cocultured for 24 hours with or without hUCMSCs at ratio of 1:10, 1:5, and 1:3 (hUCMSCs:PC-3s). PC-3 cells were placed in the lower Transwell chamber, and different numbers of hUCMSCs (hUCMSCs:PC-3s, 1:10, 1:5, 1:3) were seeded in the upper chamber. (A) Effect of hUCMSCs on the viability of PC-3 cells by MTT assay. (B) Effect of hUCMSCs on the proliferation of PC-3 cells by BrdU assay. (C) Analysis of morphology of PC-3 cells cocultured with hUCMSCs by phase-contrast microscopy. **P < 0.01, ***P < 0.001 versus untreated control.

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Stem Cell Research & Therapy

ISSN: 1757-6512