Evaluation of chromosomal modifications and in vitro transformation. A: Representative karyotype analysis of hASC-M, hASC-T, hASC-TS and hASC-TE cells at culture passage 26 evidencing alterations in all transduced-cells. B: Soft agar assay of hASCs. Only positive control gave rise to colony formation. Positive control: PC-3 cell line (tumor prostate); negative control: medium. Magnification 10X.