Figure 3
Effect of exosomes in cell viability after APAP- and H 2 O 2 -induced injury. Experiments were performed in TAMH (A-C), THLE-2 (D-F), and Huh-7 (G-I) hepatocytes. (A, D, G) Cytotoxicity of exosomes at different concentrations in respective cell lines. 0.05 μg/ml and 0.1 μg/ml of exosomes were added to respective concentration of APAP (B, E, H) and H2O2(C, F, I), and MTT were performed 24 or 72 hours later. Cell viability was normalized against vehicle control group and expressed in percentage (n = 6 per group; *P < 0.05 versus APAP or H2O2 non-exosomes-treatment group.