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Table 3 Mean expression fold differences of PERI constructs given GDF5 versus TP constructs

From: Tendon proper- and peritenon-derived progenitor cells have unique tenogenic properties

Gene

TP 7/PERI 7 + GDF5

TP 45/PERI 45 + GDF5

Scx

64.16 b

7.75 b

Tnmd

13.41 b

37.85 b

Emcn

0.21 a

0.07 b

Bgn

1.67

0.59

Dcn

1.69

3.26 a

Col1a1

2.81

1.96

Col3a1

1.38

1.30

Col5a1

1.40

1.29

Col11a1

6.46 a

6.52 a

Col12a1

2.43

2.95

Col14a1

0.84

0.39

  1. Expression Fold Differences represent the ratio of means of (Target Gene/Actb)Group A/(Target Gene/Actb)Group B. PERI: peritenon-derived progenitors; TP: tendon proper-derived progenitors. Days in culture: 7 days in construct (7), 45 days in construct (45); +: with GDF5 supplementation. Statistical significance of fold changes are in bold (aP <0.05; bP <0.01); two-tailed unpaired Mann–Whitney-Wilcoxon tests were performed. Graphical representations of the data are found in Figure 5.