Figure 4
From: Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo
Endogenous NSCs in the neurogenic niches of the rat brain are mobilized by ar-turmerone in vivo. (A) [18F]FLT-PET of a rat brain 1 week after intracerebroventricular injection of ar-turmerone shows enhanced accumulation of [18F]FLT in the subventricular zone compared with (B) Saline-injected control brain, indicating an increase of proliferating endogenous NSCs caused by ar-turmerone. (C) Ar-turmerone-treated rats showed significantly more [18F]FLT accumulation in the SVZ and the hippocampus than did control animals (mean ± SEM; **P < 0.01).