Figure 7

Histological integrity. The histological integrity was graded as restored, mild alteration, moderate alteration, and severe alteration, according to the presence of fibroblastic reaction, loss of the longitudinal axis of the fibroblasts or fibrocytes, arrangement of the collagen fibers, displacement of normal tissue structures, and recapilarization. None of the experimental groups showed any signs of severe alterations of histological integrity. Most members of group 1 (control group) had a moderate alteration, whereas groups 2 and 3 (groups that received mouse embryonic stem cells) showed a restored histological integrity (P <0.0001).