Figure 7

mRNA expression of TNF-α, IL-8, IL-1β, TGF-β, ICOSL, and IDO in MSCs. Semi-quantitative analysis of TNF-α, IL-8, IL-1β, TGF-β, ICOSL, IDO mRNA expression in non-stimulated MSCs (MSCs) and in MSCs stimulated with PMA plus ionomycin (MSCs + PMA + ionomycin). Statistically significant differences were considered when P <0.05 for Wilcoxon paired-sample test, comparing MSCs versus MSCs + PMA + ionomycin. ICOSL, inducible costimulatory ligand; IDO, indoleamine-2,3-dioxygenase; IL, interleukin; MSC, mesenchymal stromal cell; PMA, phorbol myristate acetate; TGF-β, transforming growth factor-beta; TNF-α, tumor necrosis factor-alpha.