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Figure 7 | Stem Cell Research & Therapy

Figure 7

From: Stimulation of Activin A/Nodal signaling is insufficient to induce definitive endoderm formation of cord blood-derived unrestricted somatic stem cells

Figure 7

{Sox17 and Brachyury levels following IDE1/2 induction. Sox17 (black bars) and Brachyury (white bars) mRNA levels for untreated and IDE1/2 treated USSC lines and untreated, spontaneously differentiated and IDE1/2 treated hESC. Sox17 and Brachyury mRNA levels were very low in untreated and IDE1/2 treated USSC lines. Sox17 and Brachyury mRNA levels were low in untreated hESC. Sox17 mRNA was significantly up-regulated in IDE1/2 treated hESC. Brachyury expression was significantly up-regulated in IDE2 treated hESC and spontaneously differentiated hESC. Data represent the mean ± SD of three PCR replicates from two cell culture replicates for each experimental treatment (*P < 0.05).

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Stem Cell Research & Therapy

ISSN: 1757-6512