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  • Erratum
  • Open Access

Erratum to: Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region

Stem Cell Research & Therapy20156:180

  • Received: 13 August 2015
  • Accepted: 13 August 2015
  • Published:

The original article was published in Stem Cell Research & Therapy 2015 6:69


Following the publication of our article [1], we noticed that some incorrect images had been incorporated into figure twoB (included here as Fig. 1b) and threeF-H (included here as Fig. 2f-h) in error. The corrected figures are given below. This correction does not change the results or conclusion of the original study.
Fig. 1
Fig. 1

Identification of human parthenogenetic embryonic stem cells. a Colony of human parthenogenetic embryonic stem cells; (b) positive staining for alkaline phosphatase; (c) normal 46, XX karyotype at passage 20; (d) positive staining for OCT4; (e) positive staining for NANOG; (f) positive staining for TRA-1-60; (D1-F1) nuclear staining with Hoechst 33342; (D2-F2) merged images for OCT4, NANOG and TRA-1-60. Bar is 100 μm

Fig. 2
Fig. 2

Differentiation abilities of human parthenogenetic embryonic stem cells. In vitro differentiated EBs displayed (a) positive AFP staining (endoderm), (b) positive SMA staining (mesoderm), (c) positive TUBULIN staining (ectoderm), and (d) expression of genes from endoderm (NF68KD), mesoderm (HBZ) and ectoderm (Albumin). Bar is 50 μm. (e) Efficiency of teratoma formation upon injection of human parthenogenetic embryonic stem cells into SCID mice; (f) neuro-ectoderm from ectoderm in teratoma; (g) cartilage from mesoderm in teratoma; (h) glandular tissue from endoderm in teratoma. Bar is 100 μm. EB, embryoid bodies; SCID, severe combined immunodeficiency



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Authors’ Affiliations

Department of Obstetrics and Gynecology, Center of Reproductive Medicine, Peking University Third Hospital, No. 49 HuaYuan North Road, HaiDian District, Beijing, 100191, People’s Republic of China
Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing, 100191, China
Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, 100191, China
Key Laboratory for Major Obstetric Diseases of Guangdong Province, the Third Affiliated Hospital of Guangzhou Medical University, No. 63, Liwan District, Guangzhou City, 510150, Guangdong Province, People’s Republic of China


  1. Yu Y, Gao Q, Zhao HC, Li R, Gao JM, Ding T, et al. Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region. Stem Cell Res Ther. 2015;6:69.PubMed CentralView ArticlePubMedGoogle Scholar


© Yu et al. 2015