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Retraction Note: BMP2 secretion from hepatocellular carcinoma cell HepG2 enhances angiogenesis and tumor growth in endothelial cells via activation of the MAPK/p38 signaling pathway

The Original Article was published on 06 August 2019

Retraction Note: Stem Cell Research & Therapy (2019) 10:237 https://doi.org/10.1186/s13287-019-1301-2

The Editors-in-chief have retracted this article. After publication, concerns were raised regarding the validity of the presented data.

Specifically:

  • Duplicated images are presented in Fig. 3g (H_shNC) and Fig. 7g (H-oeBMP2 + SB-239063);

  • Duplicated images are presented in Fig. 4d (H_shNC) and Fig. 6d (H_oeBMP2 + SB-239063);

  • Breaks appear to be present in the western blot backgrounds in Fig. 5a p-ERK1/2, p-JNK and JNK images, and the authors have been unable to provide the underlying raw data to address this;

  • One of the tumor images in Fig. 3b (H_oeBMP2) appears highly similar to that presented in Fig. 7a (shALX4) in [1].

The Editors-in-Chief therefore no longer have confidence in the presented data and the conclusions drawn.

The authors have not responded to correspondence from the editor or publisher about this retraction.

Reference

  1. Zhao X, Hu X. Downregulated long noncoding RNA LINC00313 inhibits the epithelial-mesenchymal transition, invasion, and migration of thyroid cancer cells through inhibiting the methylation of ALX4. J Cell Physiol. 2019;234(11):20992–1004. https://doi.org/10.1002/jcp.28703.

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Correspondence to Jian-Bing Wu.

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Feng, PC., Ke, XF., Kuang, HL. et al. Retraction Note: BMP2 secretion from hepatocellular carcinoma cell HepG2 enhances angiogenesis and tumor growth in endothelial cells via activation of the MAPK/p38 signaling pathway. Stem Cell Res Ther 13, 154 (2022). https://doi.org/10.1186/s13287-022-02841-z

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  • DOI: https://doi.org/10.1186/s13287-022-02841-z