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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: Human amniotic fluid-derived and dental pulp-derived stem cells seeded into collagen scaffold repair critical-size bone defects promoting vascularization

Figure 3

Comparative histologic analysis of cranial defect reconstruction 4 and 8 weeks post surgery. Comparative histologic analysis of cranial defect reconstruction by collagen, collagen + dental pulp stem cell (DPSC) or collagen + amniotic fluid stem cell (AFSC) constructs 4 and 8 weeks post surgery. (A) H & E staining of cranial defects closed with constructs 4 weeks after implant (magnified in (B) and (C) staining for Alizarin red. (D) Representative images showing samples 8 weeks after implant (magnified in (E), (F). Dotted line defines (left) the host bone and (right) the new bone. Arrowheads indicate vessels. Scale bar = 100 μM. ft, fibrous tissue; or, osteoblasts; os, osteoid.

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Stem Cell Research & Therapy

ISSN: 1757-6512