Skip to main content

Articles

Page 32 of 47

  1. Recently, cell-based therapeutic lymphangiogenesis has emerged and provided hope for lymphatic regeneration. Previous studies have demonstrated that secretomes of mesenchymal stem cells (MSCs) facilitate the r...

    Authors: Chang Youn Lee, Jin Young Kang, Soyeon Lim, Onju Ham, Woochul Chang and Dae-Hyun Jang

    Citation: Stem Cell Research & Therapy 2016 7:38

    Content type: Research

    Published on:

  2. Mesenchymal stem cells (MSCs) (also known as multipotent mesenchymal stromal cells) possess the capacity for self-renewal and multi-lineage differentiation, and their ability to enhance cutaneous wound healing...

    Authors: Dylan E. Lee, Nagi Ayoub and Devendra K. Agrawal

    Citation: Stem Cell Research & Therapy 2016 7:37

    Content type: Review

    Published on:

  3. Stem cell therapy can be used for alleviating the neuropathic pain induced by spinal cord injuries (SCIs). However, survival and differentiation of stem cells following their transplantation vary depending on ...

    Authors: Mahmoud Yousefifard, Farinaz Nasirinezhad, Homa Shardi Manaheji, Atousa Janzadeh, Mostafa Hosseini and Mansoor Keshavarz

    Citation: Stem Cell Research & Therapy 2016 7:36

    Content type: Research

    Published on:

  4. Bone marrow and adipose tissues are known sources of mesenchymal stem cells (MSCs) in horses; however, synovial tissues might be a promising alternative. The aim of this study was to evaluate phenotypic charac...

    Authors: Joice Fülber, Durvanei A. Maria, Luis Cláudio Lopes Correia da Silva, Cristina O. Massoco, Fernanda Agreste and Raquel Y. Arantes Baccarin

    Citation: Stem Cell Research & Therapy 2016 7:35

    Content type: Research

    Published on:

  5. Mechanical loading plays an important role in the regulation of extracellular matrix (ECM) homeostasis as well as pathogenesis of intervertebral disc (IVD) degeneration. The human annulus fibrosus (hAF) in the...

    Authors: Po-Hsin Chou, Shih-Tien Wang, Meng-Hua Yen, Chien-Lin Liu, Ming-Chau Chang and Oscar Kuang-Sheng Lee

    Citation: Stem Cell Research & Therapy 2016 7:34

    Content type: Research

    Published on:

  6. Periodontitis, which progressively destroys tooth-supporting structures, is one of the most widespread infectious diseases and the leading cause of tooth loss in adults. Evidence from preclinical trials and sm...

    Authors: Fa-Ming Chen, Li-Na Gao, Bei-Min Tian, Xi-Yu Zhang, Yong-Jie Zhang, Guang-Ying Dong, Hong Lu, Qing Chu, Jie Xu, Yang Yu, Rui-Xin Wu, Yuan Yin, Songtao Shi and Yan Jin

    Citation: Stem Cell Research & Therapy 2016 7:33

    Content type: Research

    Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2018 9:260

  7. Pluripotent stem cells, such as embryonic stem cells or induced pluripotent stem cells, have a great potential for regenerative medicine. Induced pluripotent stem cells, in particular, are suitable for replace...

    Authors: Toru Matsu-ura, Hiroshi Sasaki, Motoi Okada, Katsuhiko Mikoshiba and Muhammad Ashraf

    Citation: Stem Cell Research & Therapy 2016 7:30

    Content type: Research

    Published on:

  8. Human mesenchymal stromal cells (MSCs) can be isolated from different sources including bone marrow and term placenta. These two populations display distinct patterns of proliferation and differentiation in vi...

    Authors: Jan K. Maerz, Lorenzo P. Roncoroni, David Goldeck, Tanja Abruzzese, Hubert Kalbacher, Bernd Rolauffs, Peter DeZwart, Kay Nieselt, Melanie L. Hart, Gerd Klein and Wilhelm K. Aicher

    Citation: Stem Cell Research & Therapy 2016 7:29

    Content type: Research

    Published on:

  9. The use of large amounts of human multipotent mesenchymal stroma/stem cells (MSC) for cell therapies represents a desirable property in tissue engineering and banking in the field of regenerative medicine.

    Authors: Yuanyuan Yang, Catharina Melzer, Vesna Bucan, Juliane von der Ohe, Anna Otte and Ralf Hass

    Citation: Stem Cell Research & Therapy 2016 7:28

    Content type: Research

    Published on:

  10. Mesenchymal stem/progenitor cells (MSC) have shown beneficial effects in many models of disease in part by modulating excessive inflammatory and immune responses. Frequently the beneficial effects of MSC persi...

    Authors: Nikolay Bazhanov, Joni H. Ylostalo, Thomas J. Bartosh, April Tiblow, Arezoo Mohammadipoor, Andrea Foskett and Darwin J. Prockop

    Citation: Stem Cell Research & Therapy 2016 7:27

    Content type: Research

    Published on:

  11. Cystic fibrosis is one of the most frequent inherited rare diseases, caused by mutations in the cystic fibrosis transmembrane conductance regulator gene. Apart from symptomatic treatments, therapeutic protocol...

    Authors: María Vicenta Camarasa and Víctor Miguel Gálvez

    Citation: Stem Cell Research & Therapy 2016 7:26

    Content type: Method

    Published on:

    The Retraction Note to this article has been published in Stem Cell Research & Therapy 2017 8:123

  12. The soluble factors secreted by mesenchymal stem cells are thought to either support or inhibit tumor growth. Herein, we investigated whether the human lung-derived mesenchymal stem cell-conditioned medium (hl...

    Authors: Lourdes Cortes-Dericks, Laurene Froment, Gregor Kocher and Ralph A. Schmid

    Citation: Stem Cell Research & Therapy 2016 7:25

    Content type: Short report

    Published on:

  13. Kidney transplantation is the best treatment for end-stage renal disease, but its implementation is limited by organ shortage and immune rejection. Side effects of current immunosuppressive drugs, such as neph...

    Authors: Cheng Chen and Jianquan Hou

    Citation: Stem Cell Research & Therapy 2016 7:16

    Content type: Review

    Published on:

  14. Diabetic nephropathy is one of the most serious complications in patients with diabetes. At present, there are no satisfactory treatments available for diabetic nephropathy. Stem cells are currently the main c...

    Authors: Zhen-zhen Jiang, Yu-mei Liu, Xin Niu, Jian-yong Yin, Bin Hu, Shang-chun Guo, Ying Fan, Yang Wang and Nian-song Wang

    Citation: Stem Cell Research & Therapy 2016 7:24

    Content type: Research

    Published on:

  15. The characteristics and therapeutic potential of subtypes of mesenchymal stem cells (MSCs) are largely unknown. In this study, CD146+ and CD146 MSCs were separated from human umbilical cords, and their effects o...

    Authors: Cheng-Chi Wu, Fei-Lan Liu, Huey-Kang Sytwu, Chang-Youh Tsai and Deh-Ming Chang

    Citation: Stem Cell Research & Therapy 2016 7:23

    Content type: Research

    Published on:

  16. Efficacy and safety of anticancer drugs are traditionally studied using cancer cell lines and animal models. The thienodiazepine class of BET inhibitors, such as JQ1, has been extensively studied for the poten...

    Authors: Saeed Alghamdi, Irfan Khan, Naimisha Beeravolu, Christina McKee, Bryan Thibodeau, George Wilson and G. Rasul Chaudhry

    Citation: Stem Cell Research & Therapy 2016 7:22

    Content type: Research

    Published on:

  17. Adipose tissue-derived mesenchymal stromal cells (AT-MSCs) are frequently used to treat equine tendinopathies. Up to now, knowledge about the fate of autologous AT-MSCs after intralesional injection into equin...

    Authors: Florian Geburek, Kathrin Mundle, Sabine Conrad, Maren Hellige, Ulrich Walliser, Hans T. M. van Schie, René van Weeren, Thomas Skutella and Peter M. Stadler

    Citation: Stem Cell Research & Therapy 2016 7:21

    Content type: Research

    Published on:

  18. Articular cartilage has a limited potential for self-healing. Transplantation of genetically modified progenitor cells like bone marrow-derived mesenchymal stem cells (MSCs) is an attractive strategy to improv...

    Authors: Ke Tao, Janina Frisch, Ana Rey-Rico, Jagadeesh K. Venkatesan, Gertrud Schmitt, Henning Madry, Jianhao Lin and Magali Cucchiarini

    Citation: Stem Cell Research & Therapy 2016 7:20

    Content type: Research

    Published on:

  19. Recent advances in regenerative medicine place us in a unique position to improve the quality of engineered tissue. We use auricular cartilage as an exemplar to illustrate how the use of tissue-specific adult ...

    Authors: Zita M. Jessop, Muhammad Javed, Iris A. Otto, Emman J. Combellack, Siân Morgan, Corstiaan C. Breugem, Charles W. Archer, Ilyas M. Khan, William C. Lineaweaver, Moshe Kon, Jos Malda and Iain S. Whitaker

    Citation: Stem Cell Research & Therapy 2016 7:19

    Content type: Review

    Published on:

  20. Infected bone defect poses a great challenge for orthopedists because it is difficult to cure. Tissue-engineered bone based on the human mesenchymal stem cells (hMSCs), has currently taken a promising treatmen...

    Authors: Hai Wang, Xiao-Qing He, Tao Jin, Yang Li, Xin-Yu Fan, Yi Wang and Yong-Qing Xu

    Citation: Stem Cell Research & Therapy 2016 7:18

    Content type: Research

    Published on:

  21. Human induced pluripotent stem (hiPS) cells have the ability to undergo self-renewal and differentiation similarly to human embryonic stem (hES) cells. We have recently shown that hES cells under replication s...

    Authors: Joelle A. Desmarais, Christian Unger, Ivan Damjanov, Mark Meuth and Peter Andrews

    Citation: Stem Cell Research & Therapy 2016 7:17

    Content type: Short report

    Published on:

  22. Bone formation and remodeling are influenced by the inflammatory state of the local microenvironment. In this regard, macrophages are postulated to play a crucial role in modulating osteogenesis. However, the ...

    Authors: Florence Loi, Luis A. Córdova, Ruth Zhang, Jukka Pajarinen, Tzu-hua Lin, Stuart B. Goodman and Zhenyu Yao

    Citation: Stem Cell Research & Therapy 2016 7:15

    Content type: Research

    Published on:

  23. Type 1 diabetes mellitus (T1D) is characterized by autoimmune responses resulting in destruction of insulin-producing pancreatic beta cells. Multipotent mesenchymal stromal cells (MSCs) exhibit immunomodulator...

    Authors: Juliana Navarro Ueda Yaochite, Kalil Willian Alves de Lima, Carolina Caliari-Oliveira, Patricia Vianna Bonini Palma, Carlos Eduardo Barra Couri, Belinda Pinto Simões, Dimas Tadeu Covas, Júlio César Voltarelli, Maria Carolina Oliveira, Eduardo Antônio Donadi and Kelen Cristina Ribeiro Malmegrim

    Citation: Stem Cell Research & Therapy 2016 7:14

    Content type: Research

    Published on:

  24. A dynamic vasculature is a prerequisite for bone formation where the interaction of bone cells and endothelial cells is essential for both the development and the healing process of bone. Enhanced understandin...

    Authors: Stefanie Inglis, David Christensen, David I. Wilson, Janos M. Kanczler and Richard O. C. Oreffo

    Citation: Stem Cell Research & Therapy 2016 7:13

    Content type: Research

    Published on:

  25. Neural stem cells for the treatment of spinal cord injury (SCI) are of particular interest for future therapeutic use. However, until now, stem cell therapies are often limited due to the inhibitory environmen...

    Authors: Jennifer Butenschön, Tina Zimmermann, Nikolai Schmarowski, Robert Nitsch, Barbara Fackelmeier, Kevin Friedemann, Konstantin Radyushkin, Jan Baumgart, Beat Lutz and Julia Leschik

    Citation: Stem Cell Research & Therapy 2016 7:11

    Content type: Research

    Published on:

  26. Amelogenin is an extracellular matrix protein well known for its role in the organization and mineralization of enamel. Clinically, it is used for periodontal regeneration and, due to its finding also in prede...

    Authors: Iris Frasheri, Christina Ern, Christian Diegritz, Reinhard Hickel, Michael Hristov and Matthias Folwaczny

    Citation: Stem Cell Research & Therapy 2016 7:10

    Content type: Research

    Published on:

  27. Amnion-derived stem cells have been proposed for cell replacement therapy and tissue regeneration. An easily accessible cell source, the placenta, allows us to potentially establish a bio-bank of cells for imm...

    Authors: Toshio Miki, Wisia Wong, Elton Zhou, Anthony Gonzalez, Irving Garcia and Brendan H. Grubbs

    Citation: Stem Cell Research & Therapy 2016 7:8

    Content type: Research

    Published on:

  28. Mesenchymal stromal cells (MSCs) are well known for their application potential in tissue engineering. We previously reported that MSCs are able to differentiate into hepatocytes in vitro. However, conventiona...

    Authors: Hao-Hsiang Wu, Jennifer H. Ho and Oscar K. Lee

    Citation: Stem Cell Research & Therapy 2016 7:6

    Content type: Research

    Published on:

  29. Adipose-derived mesenchymal stem cells (MSCs) have been gaining fame mainly due to their vast clinical potential, simple isolation methods and minimal donor site morbidity. Adipose-derived MSCs and microvascul...

    Authors: Alina Freiman, Yulia Shandalov, Dekel Rozenfeld, Erez Shor, Sofia Segal, Dror Ben-David, Shai Meretzki, Dana Egozi and Shulamit Levenberg

    Citation: Stem Cell Research & Therapy 2016 7:5

    Content type: Research

    Published on:

  30. Identification of surface markers for prospective isolation of functionally homogenous populations of human skeletal (stromal, mesenchymal) stem cells (hMSCs) is highly relevant for cell therapy protocols. Thu...

    Authors: Linda Harkness, Walid Zaher, Nicholas Ditzel, Adiba Isa and Moustapha Kassem

    Citation: Stem Cell Research & Therapy 2016 7:4

    Content type: Research

    Published on:

  31. Expansion protocols aim at both increasing the number of umbilical cord blood (UCB) hematopoietic stem cells and progenitor cells (HSPCs) and reducing the period of neutropenia in UCB HSPC graft. Because glyco...

    Authors: Lionel Faivre, Véronique Parietti, Fernando Siñeriz, Sandrine Chantepie, Marie Gilbert-Sirieix, Patricia Albanese, Jérôme Larghero and Valérie Vanneaux

    Citation: Stem Cell Research & Therapy 2016 7:3

    Content type: Research

    Published on:

  32. Many retinal degenerative diseases are caused by the loss of retinal ganglion cells (RGCs). Autosomal dominant optic atrophy is the most common hereditary optic atrophy disease and is characterized by central ...

    Authors: Jing Chen, Hamidreza Riazifar, Min-Xin Guan and Taosheng Huang

    Citation: Stem Cell Research & Therapy 2016 7:2

    Content type: Research

    Published on:

  33. Multiple sclerosis is a demyelinating disease mostly of autoimmune origin that affects and damages the central nervous system, leading to a disabling condition. The aim of the present study was to investigate ...

    Authors: Oriana Trubiani, Sabrina Giacoppo, Patrizia Ballerini, Francesca Diomede, Adriano Piattelli, Placido Bramanti and Emanuela Mazzon

    Citation: Stem Cell Research & Therapy 2016 7:1

    Content type: Research

    Published on:

  34. The use of mesenchymal stem cells (MSCs) to treat inflammatory bowel disease (IBD) is of great interest because of their immunomodulatory properties. Damage to the enteric nervous system (ENS) is implicated in...

    Authors: Rhian Stavely, Ainsley M. Robinson, Sarah Miller, Richard Boyd, Samy Sakkal and Kulmira Nurgali

    Citation: Stem Cell Research & Therapy 2015 6:263

    Content type: Research

    Published on:

  35. Although metformin, a first-line drug for treating diabetes, may play an important role in inhibition of epithelial ovarian cancer cell growth and cancer stem cells (CSCs), metformin at low dose showed less ef...

    Authors: Rongrong Zhang, Ping Zhang, Hong Wang, Dongming Hou, Wentao Li, Guishan Xiao and Chenwei Li

    Citation: Stem Cell Research & Therapy 2015 6:262

    Content type: Research

    Published on:

  36. Heterogeneity of endothelial cells (ECs) is a hallmark of the vascular system which may impact the development and management of vascular disorders. Despite the tremendous progress in differentiation of human ...

    Authors: Gopu Sriram, Jia Yong Tan, Intekhab Islam, Abdul Jalil Rufaihah and Tong Cao

    Citation: Stem Cell Research & Therapy 2015 6:261

    Content type: Research

    Published on:

  37. Due to their intrinsic properties, stem cells are promising tools for new developments in tissue engineering and particularly for cartilage tissue regeneration. Although mesenchymal stromal/stem cells from bon...

    Authors: Loïc Reppel, Jessica Schiavi, Naceur Charif, Léonore Leger, Hao Yu, Astrid Pinzano, Christel Henrionnet, Jean-François Stoltz, Danièle Bensoussan and Céline Huselstein

    Citation: Stem Cell Research & Therapy 2015 6:260

    Content type: Research

    Published on:

  38. Recent evidence has demonstrated that cardiac progenitor cells play an essential role in the induction of angiomyogenesis in infarcted myocardium. We and others have shown that engraftment of c-kit+ cardiac stem ...

    Authors: Yu Tina Zhao, Jianfeng Du, Youfang Chen, Yaoliang Tang, Gangjian Qin, Guorong Lv, Shougang Zhuang and Ting C. Zhao

    Citation: Stem Cell Research & Therapy 2015 6:259

    Content type: Research

    Published on:

  39. Adult mesenchymal stem cells (MSCs) are considered promising candidates for cell-based therapies. Their potential utility derives primarily from their immunomodulatory activity, multi-lineage differentiation p...

    Authors: Catherine M. Kolf, Lin Song, Jeannine Helm and Rocky S. Tuan

    Citation: Stem Cell Research & Therapy 2015 6:258

    Content type: Research

    Published on:

  40. Stem cell treatment provides a promising therapy for patients with spinal cord injury (SCI). However, the applied stem cells exert their effects in different manners that are dependent on the route used for ad...

    Authors: Takashi Amemori, Jiri Ruzicka, Nataliya Romanyuk, Meena Jhanwar-Uniyal, Eva Sykova and Pavla Jendelova

    Citation: Stem Cell Research & Therapy 2015 6:257

    Content type: Research

    Published on:

  41. Promotion of bone regeneration is important for successful repair of bony defects. This study aimed to investigate whether combining bone marrow-derived mesenchymal stem cell (BMSC) sheets with platelet-rich p...

    Authors: Yiying Qi, Lie Niu, Tengfei Zhao, Zhongli Shi, Tuoyu Di, Gang Feng, Junhua Li and Zhongming Huang

    Citation: Stem Cell Research & Therapy 2015 6:256

    Content type: Research

    Published on:

  42. Molecular imaging is one of the methods to follow-up stem cell therapy by visualization in the brain. In a recent article in Stem Cell Research & Therapy, Micci et al. offer a thorough discussion of the advantage...

    Authors: Nora Sandu, Tumul Chowdhury and Bernhard Schaller

    Citation: Stem Cell Research & Therapy 2015 6:252

    Content type: Commentary

    Published on:

  43. Adult skeletal stem cells (SSCs) often exhibit limited in vitro expansion with undesirable phenotypic changes and loss of differentiation capacity. Foetal tissues offer an alternative cell source, providing SSCs ...

    Authors: David Gothard, Kelvin Cheung, Janos M. Kanczler, David I. Wilson and Richard O. C. Oreffo

    Citation: Stem Cell Research & Therapy 2015 6:251

    Content type: Research

    Published on:

Annual Journal Metrics