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  1. Previous studies have verified the dysfunction of mesenchymal stem cells (MSCs) for immunoregulation in acquired aplastic anemia (AA) patients. Exosomes derived from MSCs can partially substitute MSCs acting a...

    Authors: Shichong Wang, Jiali Huo, Yilin Liu, Lingyun Chen, Xiang Ren, Xingxin Li, Min Wang, Peng Jin, Jinbo Huang, Neng Nie, Jing Zhang, Yingqi Shao, Meili Ge and Yizhou Zheng
    Citation: Stem Cell Research & Therapy 2023 14:285
  2. T helper 2 (Th2) cells are thought to play critical roles in allergic conjunctivitis (AC). They release inflammatory cytokines to promote an allergic response in AC. Due to individual heterogeneity and long-te...

    Authors: Dongli Li, Qingjian Ou, Qi Shen, Michael Mingze Lu, Jing-Ying Xu, Caixia Jin, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Jiao Li, Lixia Lu, Guo-Tong Xu and Haibin Tian
    Citation: Stem Cell Research & Therapy 2023 14:281
  3. In vitro production of hematopoietic stem/progenitor cells (HSPCs) from human-induced pluripotent stem cells (hiPSCs) provides opportunities for fundamental research, disease modeling, and large-scale producti...

    Authors: Chuti Laowtammathron, Chanchao Lorthongpanich, Nittaya Jiamvoraphong, Pimonwan Srisook, Phatchanat Klaihmon, Pakpoom Kheolamai, Sudjit Luanpitpong and Surapol Issaragrisil
    Citation: Stem Cell Research & Therapy 2023 14:279
  4. Human induced pluripotent stem cell-derived endothelial cells (hiPSC-ECs) exhibit the potential to repair the injured heart after myocardial infarction (MI) by promoting neovascularization and cardiomyocyte su...

    Authors: Hao Li, Lu Wang, Teng Ma, Zhongmin Liu and Ling Gao
    Citation: Stem Cell Research & Therapy 2023 14:278
  5. As a kind of mesenchymal-like stromal cells, endometrial regenerative cells (ERCs) have been demonstrated effective in the treatment of Concanavalin A (Con A)-induced hepatitis. However, the therapeutic mechan...

    Authors: Hong Qin, Chenglu Sun, Dejun Kong, Yanglin Zhu, Bo Shao, Shaohua Ren, Hongda Wang, Jingyi Zhang, Yini Xu and Hao Wang
    Citation: Stem Cell Research & Therapy 2023 14:277
  6. Identification of promising targeted antigens that exhibited cancer-specific expression is a crucial step in the development of novel antibody-targeted therapies. We here aimed to investigate the anti-tumor ac...

    Authors: Hui-Qi Liu, Li-Xin Sun, Long Yu, Jun Liu, Li-Chao Sun, Zhi-Hua Yang, Xiong Shu and Yu-Liang Ran
    Citation: Stem Cell Research & Therapy 2023 14:273
  7. Though articular cartilage stem cell (ACSC)-based therapies have been demonstrated to be a promising option in the treatment of diseased joints, the wide variety of cell isolation, the unknown therapeutic targ...

    Authors: Zhi-Ling Li, Xiao-Tong Li, Rui-Cong Hao, Fei-Yan Wang, Yu-Xing Wang, Zhi-Dong Zhao, Pei-Lin Li, Bo-Feng Yin, Ning Mao, Li Ding and Heng Zhu
    Citation: Stem Cell Research & Therapy 2023 14:253
  8. Extracellular vesicles (EVs) from human umbilical cord mesenchymal stem cells (hUMSCs) are widely considered to be the best mediators for cell-free therapy. An understanding of their composition, especially RN...

    Authors: Dong Yu, Yue Mei, Ling Wang, Yunpeng Zhao, Xingfei Fan, Dong Liang, Li Li, Jie Zhu, Sisi Bi, Xue Wang, Zhongquan Qi, Lie Zhu and Yue Wang
    Citation: Stem Cell Research & Therapy 2023 14:272
  9. Inflammatory bowel disease (IBD) is a global health problem in which gut microbiota dysbiosis plays a pivotal pathogenic role. Mesenchymal stem cells (MSCs) therapy has emerged as a prospective novel tool for ...

    Authors: Airu Liu, Xiaonan Liang, Wenxin Wang, Chen Wang, Jia Song, Jinbo Guo, Donglei Sun, Dong Wang, Mei Song, Jiaming Qian and Xiaolan Zhang
    Citation: Stem Cell Research & Therapy 2023 14:271
  10. Mesenchymal stromal cells (MSCs) are excessively investigated in the context of inflammation-driven diseases, but the clinical results are often moderate. MSCs are naturally activated by inflammatory signals, ...

    Authors: Anton Selich, Jenni Fleischauer, Tina Roepke, Luisa Weisskoeppel, Melanie Galla, Constantin von Kaisenberg, Ulrich A. Maus, Axel Schambach and Michael Rothe
    Citation: Stem Cell Research & Therapy 2023 14:270
  11. The appearance of skin scars is known as one of the main side effects of skin burns. Stromal vascular fraction (SVF), as a rich source of cell populations with tissue regeneration properties, plays an importan...

    Authors: Masoumeh Roohaninasab, Fariba Khodadad, Afsaneh Sadeghzadeh-Bazargan, Najmolsadat Atefi, Sona Zare, Alireza Jafarzadeh, Seyyedeh Tahereh Rahimi, Maryam Nouri, Mohammad Ali Nilforoushzadeh, Elham Behrangi and Azadeh Goodarzi
    Citation: Stem Cell Research & Therapy 2023 14:269
  12. Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease of unknown etiology. The most common form of this disease is chronic inflammatory arthritis, which begins with inflammation of the synovia...

    Authors: Mahnaz Babaahmadi, Behnoosh Tayebi, Nima Makvand Gholipour, Mehrnaz Tayebi Kamardi, Sahel Heidari, Hossein Baharvand, Mohamadreza Baghaban Eslaminejad, Ensiyeh Hajizadeh-Saffar and Seyedeh-Nafiseh Hassani
    Citation: Stem Cell Research & Therapy 2023 14:268
  13. Recent studies have shown that mesenchymal stem cell (MSC) therapy has potential therapeutic effects for patients with end-stage liver diseases. However, a consensus on the efficacy and safety of MSCs has not ...

    Authors: Huimin Wang, Weiqi Yao, Yuyan Wang, Haibo Dong, Tengyun Dong, Wangyi Zhou, Lingling Cui, Lulu Zhao, Yu Zhang, Lei Shi and Yingan Jiang
    Citation: Stem Cell Research & Therapy 2023 14:267
  14. Polymorphic ventricular tachycardia (PMVT) is a rare genetic disease associated with structurally normal hearts which in 8% of cases can lead to sudden cardiac death, typically exercise-induced. We previously ...

    Authors: Yvonne Sleiman, Steven Reiken, Azzouz Charrabi, Fabrice Jaffré, Leah R. Sittenfeld, Jean-Luc Pasquié, Sarah Colombani, Bruce B. Lerman, Shuibing Chen, Andrew R. Marks, Jim W. Cheung, Todd Evans, Alain Lacampagne and Albano C. Meli
    Citation: Stem Cell Research & Therapy 2023 14:266
  15. Down syndrome (DS) clinical multisystem condition is generally considered the result of a genetic imbalance generated by the extra copy of chromosome 21. Recent discoveries, however, demonstrate that the molec...

    Authors: Salvatore Vaiasicca, Gianmarco Melone, David W. James, Marcos Quintela, Alessandra Preziuso, Richard H. Finnell, Robert Steven Conlan, Lewis W. Francis and Bruna Corradetti
    Citation: Stem Cell Research & Therapy 2023 14:265
  16. Mesenchymal stromal cell (MSC) transplantation can improve the left ventricular ejection fraction (LVEF) after an acute myocardial infarction (AMI). Transplanted MSCs exert a paracrine effect, which might be a...

    Authors: Armin Attar, Mohsen Farjoud Kouhanjani, Kamran Hessami, Massoud Vosough, Javad Kojuri, Mani Ramzi, Seyed Ali Hosseini, Marjan Faghih and Ahmad Monabati
    Citation: Stem Cell Research & Therapy 2023 14:264

    The Correction to this article has been published in Stem Cell Research & Therapy 2024 15:40

  17. Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical stud...

    Authors: Penghui Wei, Min Jia, Xiangyi Kong, Wenyuan Lyu, Hao Feng, Xinyi Sun, Jianjun Li and Jian-jun Yang
    Citation: Stem Cell Research & Therapy 2023 14:263
  18. The loss of germ cells and spermatogenic failure in non-obstructive azoospermia are believed to be the main causes of male infertility. Laboratory studies have used in vitro testicular models and different 3-d...

    Authors: Maryam Salem, Farnaz Khadivi, Parinaz Javanbakht, Sina Mojaverrostami, Mehdi Abbasi, Narjes Feizollahi, Yasaman Abbasi, Ehsan Heidarian and Farzane Rezaei Yazdi
    Citation: Stem Cell Research & Therapy 2023 14:262
  19. An effective treatment for acute non-arteritic ischemic optic neuropathy (NA-AION) has not been known or proven yet. Previous studies have suggested a neuroprotective effect of allogeneic bone marrow-derived m...

    Authors: Jose C. Pastor, Salvador Pastor-Idoate, Marina López-Paniagua, Marta Para, Francisco Blazquez, Esther Murgui, Verónica García and Rosa M. Coco-Martín
    Citation: Stem Cell Research & Therapy 2023 14:261
  20. Mesenchymal stromal cells (MSCs) have broad potential as a cell therapy including for the treatment of drug-resistant inflammatory conditions with abnormal T cell proliferation such as graft-versus-host diseas...

    Authors: Shu Hui Neo, Zhisheng Her, Rashidah Othman, Ching Ann Tee, Li Ching Ong, Yuehua Wang, Irwin Tan, Jaylen Tan, Yanmeng Yang, Zheng Yang, Qingfeng Chen and Laurie A. Boyer
    Citation: Stem Cell Research & Therapy 2023 14:259
  21. Stromal vascular fraction (SVF) cells, and the adipose-derived mesenchymal stem cells they contain, have shown enhanced wound healing in vitro and in vivo, yet their clinical application has been limited. In t...

    Authors: Stefan Balko, Evan Kerr, Ed Buchel, Sarvesh Logsetty and Afshin Raouf
    Citation: Stem Cell Research & Therapy 2023 14:258

    The Correction to this article has been published in Stem Cell Research & Therapy 2023 14:323

  22. Delayed healing of diabetic cutaneous wounds is one of the most common complications of type 2 diabetes mellitus (T2DM), which can bring great distress to patients. In diabetic patients, macrophages accumulate...

    Authors: Yiming Wang, Lin Jing, Xiao Lei, Zhen Ma, Bei Li, Yuanyuan Shi, Wuyang Zhang, Yuan Li, Hongzhi Zhou, Kaijin Hu, Yang Xue and Yan Jin
    Citation: Stem Cell Research & Therapy 2023 14:257
  23. Allo-HSCT is a definite approach for the management of a wide variety of lethal and debilitating malignant and non-malignant disorders. However, its two main complications, acute and chronic graft-versus-host ...

    Authors: Rashin Mohseni, Pouya Mahdavi Sharif, Maryam Behfar, Mohammad Reza Modaresi, Rohola Shirzadi, Mahta Mardani, Leila Jafari, Fahimeh Jafari, Zeynab Nikfetrat and Amir Ali Hamidieh
    Citation: Stem Cell Research & Therapy 2023 14:256
  24. CDC42 is a member of Rho GTPase family, acting as a molecular switch to regulate cytoskeleton organization and junction maturation of epithelium in organ development. Tooth root pattern is a highly complicated...

    Authors: Tao Zhou, Guoqing Chen, Yuchan Xu, Shuning Zhang, Huilin Tang, Tao Qiu and Weihua Guo
    Citation: Stem Cell Research & Therapy 2023 14:255
  25. Peripheral nerve injury (PNI) is one of the public health concerns that can result in a loss of sensory or motor function in the areas in which injured and non-injured nerves come together. Up until now, there...

    Authors: Mojdeh Salehi Namini, Fatemeh Daneshimehr, Nima Beheshtizadeh, Vahid Mansouri, Jafar Ai, Hossein Kargar Jahromi and Somayeh Ebrahimi-Barough
    Citation: Stem Cell Research & Therapy 2023 14:254
  26. This prospective clinical case series aimed to evaluate the effect of suprachoroidal implantation of mesenchymal stem cells (MSCs) in the form of spheroids as a stem cell therapy for retinitis pigmentosa (RP) ...

    Authors: Berna Özkan, Büşra Yılmaz Tuğan, Cansu Hemşinlioğlu, Gözde Sır Karakuş, Özlem Şahin and Ercüment Ovalı
    Citation: Stem Cell Research & Therapy 2023 14:252
  27. Hematopoietic stem cells (HSCs) with the ability to self-renew and differentiate are responsible for maintaining the supply of all types of blood cells. The complex and delicate microenvironment surrounding HS...

    Authors: Guolin Shi, Pan Zhang, Xi Zhang, Jing Li, Xinmin Zheng, Jinxiao Yan, Nu Zhang and Hui Yang
    Citation: Stem Cell Research & Therapy 2023 14:251
  28. Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are a promising cell-free therapy for acute lung injury (ALI). To date, no studies have investigated their biodistribution in ALI or discerned ...

    Authors: Alvin Tieu, Duncan J. Stewart, Damian Chwastek, Casey Lansdell, Dylan Burger and Manoj M. Lalu
    Citation: Stem Cell Research & Therapy 2023 14:250
  29. Cardiovascular complications significantly augment the overall COVID-19 mortality, largely due to the susceptibility of human cardiomyocytes (CMs) to SARS-CoV-2 virus. SARS-CoV-2 virus encodes 27 genes, whose ...

    Authors: Juli Liu, Shiyong Wu, Yucheng Zhang, Cheng Wang, Sheng Liu, Jun Wan and Lei Yang
    Citation: Stem Cell Research & Therapy 2023 14:249
  30. Disco-interacting protein 2 homolog B is a member of the Dip2 family encoded by the Dip2b gene. Dip2b is widely expressed in neuro-related tissues and is essential in axonal outgrowth during embryogenesis.

    Authors: Mingze Yao, Yuanqing Pan, Tinglin Ren, Caiting Yang, Yu Lei, Xiaoyu Xing, Lei Zhang, Xiaogang Cui, Yaowu Zheng, Li Xing and Changxin Wu
    Citation: Stem Cell Research & Therapy 2023 14:248
  31. Dissecting complex interactions among transcription factors (TFs), microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are central for understanding heart development and function. Although computational appr...

    Authors: Shumin Li, Bin Yan, Binbin Wu, Junhao Su, Jianliang Lu, Tak-Wah Lam, Kenneth R. Boheler, Ellen Ngar-Yun Poon and Ruibang Luo
    Citation: Stem Cell Research & Therapy 2023 14:247
  32. Inflammatory memory or trained immunity is a recently described process in immune and non-immune tissue resident cells, whereby previous exposure to inflammation mediators leads to a faster and stronger respon...

    Authors: Jacopo Morroni, Anna Benedetti, Lorenza Esposito, Marco De Bardi, Giovanna Borsellino, Carles Sanchez Riera, Lorenzo Giordani, Marina Bouche and Biliana Lozanoska-Ochser
    Citation: Stem Cell Research & Therapy 2023 14:246
  33. Despite increasing clinical investigations underscoring the efficacy and safety of adipose-derived mesenchymal stem cells (AD-MSCs) therapy in knee osteoarthritis (KOA), no article has recently reviewed the ce...

    Authors: Zongyuan Huang, Shuai Zhang, Mingde Cao, Zhujian Lin, Ling Kong, Xin Wu, Qianshi Guo, Yuxiang Ouyang and Yancheng Song
    Citation: Stem Cell Research & Therapy 2023 14:245
  34. Synovial fluid mesenchymal stem cells (SF-MSCs) originate in the synovium and contribute to the endogenous repair of damaged intra-articular tissues. Here, we clarified the relationship between their numbers a...

    Authors: Hideto Furuoka, Kentaro Endo and Ichiro Sekiya
    Citation: Stem Cell Research & Therapy 2023 14:244
  35. The capacity of skeletal muscles to regenerate relies on Pax7+ muscle stem cells (MuSC). While in vitro-amplified MuSC are activated and lose part of their regenerative capacity, in vitro-generated human muscle r...

    Authors: Axelle Bouche, Benoit Borner, Chloé Richard, Ysaline Grand, Didier Hannouche and Thomas Laumonier
    Citation: Stem Cell Research & Therapy 2023 14:243
  36. Melanocytes are an essential part of the epidermis, and their regeneration has received much attention because propagation of human adult melanocytes in vitro is too slow for clinical use. Differentiation from...

    Authors: Chie Kobori, Ryo Takagi, Ryo Yokomizo, Sakie Yoshihara, Mai Mori, Hiroto Takahashi, Palaksha Kanive Javaregowda, Tomohiko Akiyama, Minoru S. H. Ko, Kazuo Kishi and Akihiro Umezawa
    Citation: Stem Cell Research & Therapy 2023 14:242
  37. Mutations in the cardiac sodium channel gene SCN5A cause Brugada syndrome (BrS), an arrhythmic disorder that is a leading cause of sudden death and lacks effective treatment. An association between SCN5A and Wnt/...

    Authors: Dongsheng Cai, Xiaochen Wang, Yaxun Sun, Hangping Fan, Jingjun Zhou, Zongkuai Yang, Hangyuan Qiu, Jue Wang, Jun Su, Tingyu Gong, Chenyang Jiang and Ping Liang
    Citation: Stem Cell Research & Therapy 2023 14:241
  38. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can be used to treat heart diseases; however, the optimal maturity of hiPSC-CMs for effective regenerative medicine remains unclear. We ai...

    Authors: Yuki Tanaka, Shin Kadota, Jian Zhao, Hideki Kobayashi, Satomi Okano, Masaki Izumi, Yusuke Honda, Hajime Ichimura, Naoko Shiba, Takeshi Uemura, Yuko Wada, Shinichiro Chuma, Tsutomu Nakada, Shugo Tohyama, Keiichi Fukuda, Mitsuhiko Yamada…
    Citation: Stem Cell Research & Therapy 2023 14:240
  39. Lipodystrophy-associated metabolic disorders caused by Seipin deficiency lead to not only severe lipodystrophy but also neurological disorders. However, the underlying mechanism of Seipin deficiency-induced ne...

    Authors: Jing Yang, Na Yang, Huifang Zhao, Yan Qiao, Yanqiu Li, Chunfang Wang, Kah-Leong Lim, Chengwu Zhang, Wulin Yang and Li Lu
    Citation: Stem Cell Research & Therapy 2023 14:239
  40. This study aimed to explore a novel subtype classification method based on the stemness characteristics of patients with non-small cell lung cancer (NSCLC).

    Authors: Mingshan Liu, Ruihao Zhou, Wei Zou, Zhuofan Yang, Quanjin Li, Zhiguo Chen, Lei jiang and Jingtao Zhang
    Citation: Stem Cell Research & Therapy 2023 14:238
  41. Refractory epilepsy is also known as drug-resistant epilepsy with limited clinical treatment. Benefitting from its safety and easy availability, olfactory mucosa mesenchymal stem cells (OM-MSCs) are considered...

    Authors: Zheng-Zhao Liu, Yan Huang, Chun-Gu Hong, Xin Wang, Ran Duan, Jian-Yang Liu, Jia-Lin He, Da Duan, Hui Xie and Ming Lu
    Citation: Stem Cell Research & Therapy 2023 14:237
  42. Application of autologous adipose-derived stem cells (ASC) for diabetic chronic wounds has become an emerging treatment option. However, ASCs from diabetic individuals showed impaired cell function and subopti...

    Authors: Chun-Wei Li, Tai-Horng Young, Mu-Hui Wang, Ming-Ying Pei, Tsung-Yu Hsieh, Chia-Lang Hsu and Nai-Chen Cheng
    Citation: Stem Cell Research & Therapy 2023 14:236
  43. Although mesenchymal stem cell (MSC) transplantation provides an alternative strategy for end-stage liver disease (ESLD), further widespread application of MSC therapy is limited owing to low cell engraftment ...

    Authors: Shaoxiong Yu, Saihua Yu, Haiyan Liu, Naishun Liao and Xiaolong Liu
    Citation: Stem Cell Research & Therapy 2023 14:235
  44. Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease characterized by pulmonary fibrosis and lung dysfunction, ultimately leading to respiratory failure. Many preclinica...

    Authors: Qun Liu, Youkun Bi, Shaole Song, Keqi Zhu, Xinlong Qiao, Huiwen Wang and Guangju Ji
    Citation: Stem Cell Research & Therapy 2023 14:234
  45. Enteric neuropathies, which result from abnormalities of the enteric nervous system, are associated with significant morbidity and high health-care costs, but current treatments are unsatisfactory. Cell-based ...

    Authors: Ryo Hotta, Ahmed Rahman, Sukhada Bhave, Rhian Stavely, Weikang Pan, Shriya Srinivasan, Geoffrey de Couto, Luis Rodriguez-Borlado, Richard Myers, Alan J. Burns and Allan M. Goldstein
    Citation: Stem Cell Research & Therapy 2023 14:232

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