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  1. Mesenchymal stromal cells (MSCs) show considerable promise in regenerative medicine with superior anti-fibrotic, immunomodulatory, and angiogenic functions. More recently, discovered with the tumor tropism, MS...

    Authors: Yizuo Song, Hejing Liu, Shuya Pan, Xinli Xiang, Miaomiao Ye and Xueqiong Zhu
    Citation: Stem Cell Research & Therapy 2023 14:347
  2. Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is requir...

    Authors: Vanessa S. Fear, Catherine A. Forbes, Nicole C. Shaw, Kathryn O. Farley, Jessica L. Mantegna, Jasmin P. Htun, Genevieve Syn, Helena Viola, Henrietta Cserne Szappanos, Livia Hool, Michelle Ward, Gareth Baynam and Timo Lassmann
    Citation: Stem Cell Research & Therapy 2023 14:345
  3. Mesenchymal stromal cells (MSCs) have regenerative and immunomodulatory properties, making them suitable for cell therapy. Toll-like receptors (TLRs) in MSCs respond to viral load by secreting immunosuppressiv...

    Authors: Tatiana Tolstova, Ekaterina Dotsenko, Peter Kozhin, Svetlana Novikova, Victor Zgoda, Alexander Rusanov and Nataliya Luzgina
    Citation: Stem Cell Research & Therapy 2023 14:344
  4. The Wnt signaling pathway has been implicated in the pathogenesis of fibrotic disorders and malignancies. Hence, we aimed to assess the potential of the induced pluripotent stem cells (IPS) in modulating the e...

    Authors: Paria Bayati, Marjan Taherian, Mansoureh Soleimani, Hamid Farajifard and Nazanin Mojtabavi
    Citation: Stem Cell Research & Therapy 2023 14:343
  5. Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial cells undergo a reversible phenotype switch via the loss of adhesion capacity and acquisition of mesenchymal characteris...

    Authors: Raheleh Farahzadi, Behnaz Valipour, Ezzatollah Fathi, Samaneh Pirmoradi, Ommoleila Molavi, Soheila Montazersaheb and Zohreh Sanaat
    Citation: Stem Cell Research & Therapy 2023 14:342
  6. The functional impairment of adipose stem cells (ASCs) during aging limits their clinical transformation. Studies have shown that extrachromosomal circular DNAs (eccDNAs) are associated with tumor progression ...

    Authors: Sen Ren, Du Wu, Xiaoyong Shen, Qian Wu, Chengcheng Li, Hewei Xiong, Zhongwei Xiong, Rui Gong, Zheng Liu, Wei Wang and Jincao Chen
    Citation: Stem Cell Research & Therapy 2023 14:341
  7. Inherited retinal diseases (IRDs) can induce severe sight-threatening retinal degeneration and impose a considerable economic burden on patients and society, making efforts to cure blindness imperative. Transg...

    Authors: Yuqin Liang, Xihao Sun, Chunwen Duan, Shibo Tang and Jiansu Chen
    Citation: Stem Cell Research & Therapy 2023 14:340
  8. The secretome of mesenchymal stromal cells isolated from the amniotic membrane (hAMSCs) has been extensively studied for its in vitro immunomodulatory activity as well as for the treatment of several preclinic...

    Authors: Alexandra Muntiu, Andrea Papait, Federica Vincenzoni, Alberto Vitali, Wanda Lattanzi, Pietro Romele, Anna Cargnoni, Antonietta Silini, Ornella Parolini and Claudia Desiderio
    Citation: Stem Cell Research & Therapy 2023 14:339
  9. Contrast-induced nephropathy (CIN) is a major clinical problem associated with acute kidney injury during hospitalization. However, effective treatments for CIN are currently lacking. Mesenchymal stem cells (M...

    Authors: Mitsuki Kadono, Ayumu Nakashima, Naoki Ishiuchi, Kensuke Sasaki, Yoshie Miura, Satoshi Maeda, Asuka Fujita, Ayano Sasaki, Shogo Nagamatsu and Takao Masaki
    Citation: Stem Cell Research & Therapy 2023 14:337
  10. Kidney organoids derived from human pluripotent stem cells (HiPSCs) hold huge applications for drug screening, disease modeling, and cell transplanting therapy. However, these applications are limited since ki...

    Authors: Kexin Peng, Wanqin Xie, Tingting Wang, Yamei Li, Jean de Dieu Habimana, Obed Boadi Amissah, Jufang Huang, Yong Chen, Bin Ni and Zhiyuan Li
    Citation: Stem Cell Research & Therapy 2023 14:336
  11. The metabolic reprogramming of mesenchymal stem/stromal cells (MSC) favoring glycolysis has recently emerged as a new approach to improve their immunotherapeutic abilities. This strategy is associated with gre...

    Authors: Carolina Pradenas, Noymar Luque-Campos, Karina Oyarce, Rafael Contreras-Lopez, Felipe A. Bustamante-Barrientos, Andrés Bustos, Felipe Galvez-Jiron, María Jesús Araya, Catalina Asencio, Raúl Lagos, Yeimi Herrera-Luna, Daouda Abba Moussa, Charlotte Nicole Hill, Eliana Lara-Barba, Claudia Altamirano, Alexander Ortloff…
    Citation: Stem Cell Research & Therapy 2023 14:335
  12. Mesenchymal stem cells (MSCs) are adult stem cells with self-renewal and multi-directional differentiation potential and possess the functions of immunomodulation, regulation of cell growth, and repair of dama...

    Authors: Jingfang Xiao, Xiaoyuan Gong, Zhenlan Fu, Xiongbo Song, Qinghua Ma, Jingya Miao, Ruili Cai, Zexuan Yan, Shuai Wang, Qian Li, Yaokai Chen, Liu Yang, Xiuwu Bian and Yemiao Chen
    Citation: Stem Cell Research & Therapy 2023 14:334
  13. Assisted reproduction faces a significant obstacle in the form of poor ovarian response (POR) to controlled ovarian stimulation. To address this challenge, mesenchymal stem cell therapy has been proposed as a ...

    Authors: Simin Zafardoust, Somaieh Kazemnejad, Mina Fathi-Kazerooni, Maryam Darzi, Mohammad Reza Sadeghi, Ali Sadeghi Tabar and Zahra Sehat
    Citation: Stem Cell Research & Therapy 2023 14:332
  14. Acute compartment syndrome (ACS) is one of the most common complications of musculoskeletal injury, leading to the necrosis and demise of skeletal muscle cells. Our previous study showed that embryonic stem ce...

    Authors: Xiangkang Jiang, Jingyuan Yang, Yao Lin, Fei Liu, Jiawei Tao, Wenbin Zhang, Jiefeng Xu and Mao Zhang
    Citation: Stem Cell Research & Therapy 2023 14:331
  15. A non-invasive imaging technology that can monitor cell viability, retention, distribution, and interaction with host tissue after transplantation is needed for optimizing and translating stem cell-based thera...

    Authors: Keyu Zhuang, Rocco Romagnuolo, Tamilla Sadikov Valdman, Kyle D. W. Vollett, Daniel A. Szulc, Hai-Ying Mary Cheng, Michael A. Laflamme and Hai-Ling Margaret Cheng
    Citation: Stem Cell Research & Therapy 2023 14:330
  16. Mesenchymal stem cells (MSCs) have immunomodulatory properties and therapeutic effects on autoimmune diseases through their secreted factors, referred to as the secretome. However, the specific key factors of ...

    Authors: Eunhee Ko, Taejun Yoon, Yoojin Lee, Jongsun Kim and Yong-Beom Park
    Citation: Stem Cell Research & Therapy 2023 14:329
  17. Mesenchymal stem cells (MSCs) have shown promising potential in allograft survival. However, few reports have focused on comparing the immunosuppressive capacity of MSCs from different sources and administered...

    Authors: Huanmin Kang, Jianing Feng, Yingqian Peng, Yingyi Liu, Yalei Yang, Ying Wu, Jian Huang, Ying Jie, Baihua Chen and Yan He
    Citation: Stem Cell Research & Therapy 2023 14:328
  18. Chemotherapy can cause ovarian dysfunction and infertility since the ovary is extremely sensitive to chemotherapeutic drugs. Apart from the indispensable role of the ovary in the overall hormonal milieu, ovari...

    Authors: Shenghui Zhang, Badrul Hisham Yahaya, Ying Pan, Yanli Liu and Juntang Lin
    Citation: Stem Cell Research & Therapy 2023 14:327
  19. In regenerative medicine, especially skin tissue engineering, the focus is on enhancing the quality of wound healing. Also, several constructs with different regeneration potentials have been used for skin tis...

    Authors: Maryam Ghahremani-nasab, Naeimeh Akbari‑Gharalari, Azizeh Rahmani Del Bakhshayesh, Armita Ghotaslou, Abbas Ebrahimi-kalan, Mahdi Mahdipour and Ahmad Mehdipour
    Citation: Stem Cell Research & Therapy 2023 14:326
  20. Stromal vascular fraction (SVF) treatment promoted the regeneration of the intestinal epithelium, limiting lethality in a mouse model of radiation-induced gastrointestinal syndrome (GIS). The SVF has a heterog...

    Authors: Lydia Bensemmane, Fabien Milliat, Xavier Treton and Christine Linard
    Citation: Stem Cell Research & Therapy 2023 14:325
  21. Diabetes mellitus (DM) constitutes a chronic metabolic disease characterized by elevated levels of blood glucose which can also lead to the so-called diabetic vascular complications (DVCs), responsible for mos...

    Authors: Josefa Benítez-Camacho, Antonio Ballesteros, Lucía Beltrán-Camacho, Marta Rojas-Torres, Antonio Rosal-Vela, Margarita Jimenez-Palomares, Ismael Sanchez-Gomar and Mª Carmen Durán-Ruiz
    Citation: Stem Cell Research & Therapy 2023 14:324
  22. Cardiac pathological outcome of metabolic remodeling is difficult to model using cardiomyocytes derived from human-induced pluripotent stem cells (hiPSC-CMs) due to low metabolic maturation.

    Authors: Dong Li, Lawrence C. Armand, Fangxu Sun, Hyun Hwang, David Wolfson, Antonio Rampoldi, Rui Liu, Parvin Forghani, Xin Hu, Wen-Mei Yu, Cheng-Kui Qu, Dean P. Jones, Ronghu Wu, Hee Cheol Cho, Joshua T. Maxwell and Chunhui Xu
    Citation: Stem Cell Research & Therapy 2023 14:322
  23. Macrophage polarization has been observed in the process of muscle injuries including rotator cuff (RC) muscle atrophy and fatty infiltration after large tendon tears. In our previous study, we showed that fib...

    Authors: Mengyao Liu, Martin Ng, Tuan Phu, Laura Bouchareychas, Brian T. Feeley, Hubert T. Kim, Robert L. Raffai and Xuhui Liu
    Citation: Stem Cell Research & Therapy 2023 14:321
  24. Human mitochondrial DNA mutations are associated with common to rare mitochondrial disorders, which are multisystemic with complex clinical pathologies. The pathologies of these diseases are poorly understood ...

    Authors: Fibi Meshrkey, Kelly M. Scheulin, Christopher M. Littlejohn, Joshua Stabach, Bibhuti Saikia, Vedant Thorat, Yimin Huang, Thomas LaFramboise, Edward J. Lesnefsky, Raj R. Rao, Franklin D. West and Shilpa Iyer
    Citation: Stem Cell Research & Therapy 2023 14:320
  25. Ever since their discovery, induced pluripotent stem cells (iPSCs) have been extensively differentiated into a large variety of cell types. However, a limited amount of work has been dedicated to differentiati...

    Authors: Alexander Blümke, Erica Ijeoma, Jessica Simon, Rachel Wellington, Medania Purwaningrum, Sergei Doulatov, Elizabeth Leber, Marta Scatena and Cecilia M. Giachelli
    Citation: Stem Cell Research & Therapy 2023 14:319
  26. Immunologically impaired individuals respond poorly to vaccines, highlighting the need for additional strategies to protect these vulnerable populations from COVID-19. While monoclonal antibodies (mAbs) have e...

    Authors: Evan Sawula, Shane Miersch, Eric D. Jong, Chengjin Li, Fang-Yu Chou, Jean Kit Tang, Reza Saberianfar, Jeffrey Harding, Sachdev S. Sidhu and Andras Nagy
    Citation: Stem Cell Research & Therapy 2023 14:318
  27. Autoimmune hepatitis (AIH) is a T-cell-mediated autoimmune liver disease that can lead to liver injury and has a poor long-term prognosis. Mesenchymal stromal cells (MSCs) have immunosuppressive effects and ca...

    Authors: Wenbin Ji, Weiwei Wang, Peiyuan Li, Yanhong Liu, Baotong Zhang and Feng Qi
    Citation: Stem Cell Research & Therapy 2023 14:316
  28. Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are used in regenerative medicine and related research involving immunomodulatory, anti-inflammatory, anti-fibrotic and regenerative functions. Isolation...

    Authors: Maximilian Handke, Anastasia Rakow, Debora Singer, Lea Miebach, Frank Schulze, Sander Bekeschus, Janosch Schoon and Georgi I. Wassilew
    Citation: Stem Cell Research & Therapy 2023 14:315
  29. Human pluripotent stem cell (hPSC)-derived hepatocyte-like cells (HLCs) can provide a valuable in vitro model for disease modelling and drug development. However, generating HLCs with characteristics comparabl...

    Authors: Faiza Farhan, Manjari Trivedi, Priscilla Di Wu and Wei Cui
    Citation: Stem Cell Research & Therapy 2023 14:314
  30. Prolonged air leak (PAL) is the most frequent complication after pulmonary resection. Several measures have been described to prevent the occurrence of PAL in high-risk patients, however, the potential role of...

    Authors: Marcelo F. Jiménez, María Teresa Gómez-Hernández, Eva M. Villarón, Miriam López-Parra and Fermín Sánchez-Guijo
    Citation: Stem Cell Research & Therapy 2023 14:313
  31. Thymic epithelial cells (TECs) are responsible for shaping the repertoires of T cells, where their postnatal regeneration depends on a subset of clonogenic TECs. Despite the implications for regenerative medic...

    Authors: Juan M. Ocampo-Godinez, Jose L. Gonzalez-Quiroz, Hector Cote-Palafox, Elizabeth George, Jael A. Vergara-Lope Nuñez, Guillermo Villagomez-Olea, Febe C. Vazquez-Vazquez, Edgar O. Lopez-Villegas, Gloria Leon-Avila, Maria L. Dominguez-Lopez and Marco A. Alvarez-Perez
    Citation: Stem Cell Research & Therapy 2023 14:312

    The Correction to this article has been published in Stem Cell Research & Therapy 2024 15:39

  32. The aim of the study was to evaluate the efficacy and safety of allogeneic umbilical cord-derived mesenchymal stem cells (TH-SC01) for complex perianal fistula in patients with Crohn’s disease (CD).

    Authors: Juan Wei, Yufei Zhang, Chunyan Chen, Xiaoyue Feng, Zhao Yang, Jing Feng, Qiong Jiang, Jinjin Fu, Ji Xuan, Hong Gao, Lianming Liao and Fangyu Wang
    Citation: Stem Cell Research & Therapy 2023 14:311
  33. Authors: Ruiying Wang, Min Wang, Shan Wang, Ke Yang, Ping Zhou, Xueheng Xie, Qi Cheng, Jingxue Ye, Guibo Sun and Xiaobo Sun
    Citation: Stem Cell Research & Therapy 2023 14:310

    The original article was published in Stem Cell Research & Therapy 2019 10:20

  34. Pseudoenzymes, catalytically deficient variants of active enzymes, have a wide range of regulatory functions. ADP-ribosylhydrolase-like 1 (ADPRHL1), a pseudoenzyme belonging to a small group of ADP-ribosylhydr...

    Authors: Lei Tian, Tianwei Guo, Fujian Wu, Rui Bai, Sinan Ai, Hongyue Wang, Yuanxiu Song, Min Zhu, Youxu Jiang, Shuhong Ma, Xiaofeng Zhuang and Shuzhen Guo
    Citation: Stem Cell Research & Therapy 2023 14:309
  35. Stem cell transplantation is an emerging therapy for severe cardiomyopathy, proffering stem cell recruitment, anti-apoptosis, and proangiogenic capabilities. Angiogenic cell precursors (ACP-01) are autologous,...

    Authors: Jane R. Schubart, Amirhossein Zare, Roberto M. Fernandez-de-Castro, Hector Rosario Figueroa, Ina Sarel, Kelly Tuchman, Kaitlyn Esposito, Fraser C. Henderson and Ernst von Schwarz
    Citation: Stem Cell Research & Therapy 2023 14:308
  36. Tendinopathy is a debilitating and crippling syndrome resulting from the degeneration of tendon tissue, leading to loss of mechanical properties and function, and eventual tendon rupture. Unfortunately, there ...

    Authors: Yuxiang Zhang, Wei Ju, Hong Zhang, Liu Mengyun, Weiliang Shen and Xiao Chen
    Citation: Stem Cell Research & Therapy 2023 14:307
  37. Skin tissue engineering is a rapidly evolving field of research that effectively combines stem cells and biological scaffolds to replace damaged tissues. Human Wharton’s jelly mesenchymal stromal cells (hWJ-MS...

    Authors: Luz Correa-Araujo, Leonardo Prieto-Abello, Adriana Lara-Bertrand, Martha Medina-Solano, Linda Guerrero, Bernardo Camacho and Ingrid Silva-Cote
    Citation: Stem Cell Research & Therapy 2023 14:306
  38. The therapeutic application of multipotent mesenchymal stem cells (MSCs) encounters significant challenges, primarily stemming from their inadequate growth and limited self-renewal capabilities. Additionally, ...

    Authors: Matteo Mazzella, Keegan Walker, Christina Cormier, Michael Kapanowski, Albi Ishmakej, Azeem Saifee, Yashvardhan Govind and G. Rasul Chaudhry
    Citation: Stem Cell Research & Therapy 2023 14:305
  39. Umbilical cord blood transplantation (UCBT) is a curable therapy for hematological disease; however, the impact of nutritional status on UCBT outcomes remains controversial. To evaluate the joint effect of cli...

    Authors: Meijuan Tu, Aijie Huang, Lijuan Ning, Baolin Tang, Chunli Zhang, Guangyu Sun, Xiang Wan, Kaidi Song, Wen Yao, Ping Qiang, Yue Wu and Xiaoyu Zhu
    Citation: Stem Cell Research & Therapy 2023 14:304
  40. There is growing interest to application of regenerative medicine approaches in otorhinolaryngological practice, especially in the framework of the therapy of vocal fold (VF) scar lesions. The used conservativ...

    Authors: Mikhail Svistushkin, Anastasia Shpichka, Polina Bikmulina, Alexey Fayzullin, Anna Zolotova, Nastasia Kosheleva, Liliya Selezneva, Boris Shavkuta, Viktoria Lobacheva, Anna Nikiforova, Peter Kochetkov, Svetlana Kotova, Svetlana Starostina, Anatoly Shekhter, Andrey Svistunov, Valeriy Svistushkin…
    Citation: Stem Cell Research & Therapy 2023 14:303
  41. Although the efficacy and safety of mesenchymal stem cell therapy for liver cirrhosis have been demonstrated in several studies. Clinical cases of mesenchymal stem cell therapy for patients with liver cirrhosi...

    Authors: Wenming Lu, Jiayang Qu, Longxiang Yan, Xingkun Tang, Xuesong Wang, Anqi Ye, Zhengwei Zou, Lincai Li, Junsong Ye and Lin Zhou
    Citation: Stem Cell Research & Therapy 2023 14:301
  42. Granulocyte colony-stimulating factor (G-CSF)-mediated mobilization of hematopoietic stem cells (HSCs) is a well-established method to prepare HSCs for transplantation nowadays. A sufficient number of HSCs is ...

    Authors: Tso-Fu Wang, Yu-Shan Liou, Shang-Hsien Yang, Guan-Ling Lin, Ya-Wen Chiang, Te-Sheng Lien, Chi-Cheng Li, Jen-Hung Wang, Hsin-Hou Chang and Der-Shan Sun
    Citation: Stem Cell Research & Therapy 2023 14:300
  43. Authors: Yun Xu, Masoud Nasri, Benjamin Dannenmann, Perihan Mir, Azadeh Zahabi, Karl Welte, Tatsuya Morishima and Julia Skokowa
    Citation: Stem Cell Research & Therapy 2023 14:299

    The original article was published in Stem Cell Research & Therapy 2021 12:112

  44. Treatments for skin injuries have recently advanced tremendously. Such treatments include allogeneic and xenogeneic transplants and skin substitutes such as tissue-engineered skin, cultured cells, and stem cel...

    Authors: Wan Tai Seet, Mohd Asyraf Mat Afandi, Mohamad Fikeri Ishak, Muhammad Najib Fathi Hassan, Nazeha Ahmat, Min Hwei Ng and Manira Maarof
    Citation: Stem Cell Research & Therapy 2023 14:298
  45. Menstrual blood-derived cells show regenerative potential as a mesenchymal stem cell and may therefore be a novel stem cell source of treatment for refractory infertility with injured endometrium. However, the...

    Authors: Satoshi Hosoya, Ryo Yokomizo, Harue Kishigami, Yukiko Fujiki, Erika Kaneko, Mitsuyoshi Amita, Takakazu Saito, Hiroshi Kishi, Haruhiko Sago, Aikou Okamoto and Akihiro Umezawa
    Citation: Stem Cell Research & Therapy 2023 14:297
  46. Natural killer (NK) cells hold great promise in treating diverse hematopoietic and solid tumors. Despite their availability from peripheral blood and cord blood, stem cell-derived NK cells offer an 'off-the-sh...

    Authors: Wei Wen, Xiang Chen, Xin-Yi Shen, Hua-Yu Li, Feng Zhang, Feng-Qi Fang and Xiao-Bing Zhang
    Citation: Stem Cell Research & Therapy 2023 14:295

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