Coecke S, Balls M, Bowe G, Davis J, Gstraunthaler G, Hartung T, Hay R, Merten OW, Price A, Schechtman L, Stacey G, Stokes W: Guidance on Good Cell Culture Practice. A report of the Second ECVAM task force on good cell culture practice. Altern Lab Anim. 2005, 33: 261-287.
CAS
PubMed
Google Scholar
Grandjean P, Landrigan PJ: Developmental neurotoxicity of industrial chemicals. Lancet. 2006, 368: 2167-2178. 10.1016/S0140-6736(06)69665-7.
Article
CAS
PubMed
Google Scholar
National Center on Birth Defects and Developmental Disabilities. [http://www.cdc.gov/ncbddd/index.html]
OECD: Test No. 426: developmental neurotoxicity study. OECD Guidelines for the Testing of Chemicals/Section 4: Health Effects. 2007, OECD, [http://www.oecd-ilibrary.org/environment/test-no-426-developmental-neurotoxicity-study_9789264067394-en]
Google Scholar
US Environmental Protection Agency: Health Effects Guidelines OPPTS 870.6300. 1998, US EPA, [http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0156-0042]
Google Scholar
Tsuji R, Crofton KM: Developmental neurotoxicity guideline study: issues with methodology, evaluation and regulation. Congeni Anom (Kyoto). 2012, 52: 122-128. 10.1111/j.1741-4520.2012.00374.x.
Article
Google Scholar
Limongi T, Cesca F, Gentile F, Marotta R, Ruffilli R, Barberis A, Dal Maschio M, Petrini EM, Santoriello S, Benfenati F, Di Fabrizio E: Nanostructured superhydrophobic substrates trigger the development of 3D neuronal networks. Small. 2013, 9: 402-412. 10.1002/smll.201201377.
Article
CAS
PubMed
Google Scholar
Eskes C, Juillerat-Jeanneret L, Leuba G, Honegger P, Monnet-Tschudi F: Involvement of microglia-neuron interactions in the tumor necrosis factor-alpha release, microglial activation, and neurodegeneration induced by trimethyltin. J Neurosci Res. 2003, 71: 583-590. 10.1002/jnr.10508.
Article
CAS
PubMed
Google Scholar
van Vliet E, Morath S, Eskes C, Linge J, Rappsilber J, Honegger P, Hartung T, Coecke S: A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine. Neurotoxicology. 2008, 29: 1-12. 10.1016/j.neuro.2007.09.007.
Article
CAS
PubMed
Google Scholar
van Vliet E, Stoppini L, Balestrino M, Eskes C, Griesinger C, Sobanski T, Whelan M, Hartung T, Coecke S: Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects. Neurotoxicology. 2007, 28: 1136-1146. 10.1016/j.neuro.2007.06.004.
Article
CAS
PubMed
Google Scholar
Zurich MG, Honegger P: Ochratoxin A at nanomolar concentration perturbs the homeostasis of neural stem cells in highly differentiated but not in immature three-dimensional brain cell cultures. Toxicol Lett. 2011, 205: 203-208. 10.1016/j.toxlet.2011.06.007.
Article
CAS
PubMed
Google Scholar
Zurich MG, Honegger P, Schilter B, Costa LG, Monnet-Tschudi F: Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. Toxicol Appl Pharmacol. 2004, 201: 97-104. 10.1016/j.taap.2004.05.003.
Article
CAS
PubMed
Google Scholar
Coecke S, Goldberg AM, Allen S, Buzanska L, Calamandrei G, Crofton K, Hareng L, Hartung T, Knaut H, Honegger P, Jacobs M, Lein P, Li A, Mundy W, Owen D, Schneider S, Silbergeld E, Reum T, Trnovec T, Monnet-Tschudi F, Bal-Price A: Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies. Environ Health Perspect. 2007, 115: 924-931. 10.1289/ehp.9427.
Article
PubMed Central
PubMed
Google Scholar
Lein P, Locke P, Goldberg A: Meeting report: alternatives for developmental neurotoxicity testing. Environ Health Perspect. 2007, 115: 764-768. 10.1289/ehp.9841.
Article
PubMed Central
PubMed
Google Scholar
Lein P, Silbergeld E, Locke P, Goldberg AM: In vitro and other alternative approaches to developmental neurotoxicity testing (DNT). Environ Toxicol Pharmacol. 2005, 19: 735-744. 10.1016/j.etap.2004.12.035.
Article
CAS
PubMed
Google Scholar
Challenge and Opportunity on the Critical Path to New Medical Products. [http://www.fda.gov/ScienceResearch/SpecialTopics/CriticalPathInitiative/CriticalPathOpportunitiesReports/ucm077262.htm]
Zhang SC, Wernig M, Duncan ID, Brustle O, Thomson JA: In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol. 2001, 19: 1129-1133. 10.1038/nbt1201-1129.
Article
CAS
PubMed
Google Scholar
Moors M, Rockel TD, Abel J, Cline JE, Gassmann K, Schreiber T, Schuwald J, Weinmann N, Fritsche E: Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing. Environ Health Perspect. 2009, 117: 1131-1138. 10.1289/ehp.0800207.
Article
PubMed Central
CAS
PubMed
Google Scholar
Stummann TC, Hareng L, Bremer S: Hazard assessment of methylmercury toxicity to neuronal induction in embryogenesis using human embryonic stem cells. Toxicology. 2009, 257: 117-126. 10.1016/j.tox.2008.12.018.
Article
CAS
PubMed
Google Scholar
Yla-Outinen L, Heikkila J, Skottman H, Suuronen R, Aanismaa R, Narkilahti S: Human cell-based micro electrode array platform for studying neurotoxicity. Front Neuroeng. 2010, 3:
Google Scholar
Buzanska L, Sypecka J, Nerini-Molteni S, Compagnoni A, Hogberg HT, del Torchio R, Domanska-Janik K, Zimmer J, Coecke S: A human stem cell-based model for identifying adverse effects of organic and inorganic chemicals on the developing nervous system. Stem Cells. 2009, 27: 2591-2601. 10.1002/stem.179.
Article
CAS
PubMed
Google Scholar
Alexanian AR: An efficient method for generation of neural-like cells from adult human bone marrow-derived mesenchymal stem cells. Regen Med. 2010, 5: 891-900. 10.2217/rme.10.67.
Article
CAS
PubMed
Google Scholar
Hung SC, Cheng H, Pan CY, Tsai MJ, Kao LS, Ma HL: In vitro differentiation of size-sieved stem cells into electrically active neural cells. Stem Cells. 2002, 20: 522-529. 10.1634/stemcells.20-6-522.
Article
CAS
PubMed
Google Scholar
Ayuso-Sacido A, Roy NS, Schwartz TH, Greenfield JP, Boockvar JA: Long-term expansion of adult human brain subventricular zone precursors. Neurosurgery. 2008, 62: 223-229. 10.1227/01.NEU.0000311081.50648.4C. discussion 229-231
Article
PubMed
Google Scholar
Hu BY, Zhang SC: Differentiation of spinal motor neurons from pluripotent human stem cells. Nat Protoc. 2009, 4: 1295-1304. 10.1038/nprot.2009.127.
Article
PubMed Central
CAS
PubMed
Google Scholar
Caldwell MA, He X, Wilkie N, Pollack S, Marshall G, Wafford KA, Svendsen CN: Growth factors regulate the survival and fate of cells derived from human neurospheres. Nat Biotechnol. 2001, 19: 475-479. 10.1038/88158.
Article
CAS
PubMed
Google Scholar
Colombo E, Giannelli SG, Galli R, Tagliafico E, Foroni C, Tenedini E, Ferrari S, Corte G, Vescovi A, Cossu G, Broccoli V: Embryonic stem-derived versus somatic neural stem cells: a comparative analysis of their developmental potential and molecular phenotype. Stem Cells. 2006, 24: 825-834. 10.1634/stemcells.2005-0313.
Article
PubMed
Google Scholar
Emdad L, D'Souza SL, Kothari HP, Qadeer ZA, Germano IM: Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes. Stem cells and development. Stem Cells Dev. 2011, 21: 404-410.
Article
PubMed
Google Scholar
Chiang CH, Su Y, Wen Z, Yoritomo N, Ross CA, Margolis RL, Song H, Ming GL: Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation. Mol Psychiatry. 2011, 16: 358-360. 10.1038/mp.2011.13.
Article
PubMed Central
CAS
PubMed
Google Scholar
Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, Hefferan MP, Vidal JG, Mu Y, Killian RL, Israel MA, Emre N, Marsala S, Marsala M, Gage FH, Goldstein LS, Carson CT: Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PloS One. 2011, 6: e17540-10.1371/journal.pone.0017540.
Article
PubMed Central
CAS
PubMed
Google Scholar
Liu H, Zhang SC: Specification of neuronal and glial subtypes from human pluripotent stem cells. Cell Mol Life Sci. 2011, 68: 3995-4008. 10.1007/s00018-011-0770-y.
Article
PubMed Central
CAS
PubMed
Google Scholar
Nat R, Dechant G: Milestones of directed differentiation of mouse and human embryonic stem cells into telencephalic neurons based on neural development in vivo. Stem Cells Dev. 2011, 20: 947-958. 10.1089/scd.2010.0417.
Article
PubMed
Google Scholar
Wu H, Xu J, Pang ZP, Ge W, Kim KJ, Blanchi B, Chen C, Sudhof TC, Sun YE: Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci USA. 2007, 104: 13821-13826. 10.1073/pnas.0706199104.
Article
PubMed Central
CAS
PubMed
Google Scholar
Honegger PaM-T, F : Aggregating neural cell cultures. Protocols for Neural Cell Cultures. Edited by: Fedoroff S. 2001, Totowa, NJ: Humana Press, 199-218. 1
Chapter
Google Scholar
Hogberg HT, Kinsner-Ovaskainen A, Coecke S, Hartung T, Bal-Price AK: mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach. Toxicol Sci. 2010, 113: 95-115. 10.1093/toxsci/kfp175.
Article
CAS
PubMed
Google Scholar
Hogberg HT, Kinsner-Ovaskainen A, Hartung T, Coecke S, Bal-Price AK: Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides. Toxicol Appl Pharmacol. 2009, 235: 268-286. 10.1016/j.taap.2008.12.014.
Article
CAS
PubMed
Google Scholar
Franceschi C, Monti D, Scarfi MR, Zeni O, Temperani P, Emilia G, Sansoni P, Lioi MB, Troiano L, Agnesini C: Genomic instability and aging. Studies in centenarians (successful aging) and in patients with Down's syndrome (accelerated aging). Ann N Y Acad Sci. 1992, 663: 4-16. 10.1111/j.1749-6632.1992.tb38643.x.
Article
CAS
PubMed
Google Scholar
De Felice C, Ciccoli L, Leoncini S, Signorini C, Rossi M, Vannuccini L, Guazzi G, Latini G, Comporti M, Valacchi G, Hayek J: Systemic oxidative stress in classic Rett syndrome. Free Radic Biol Med. 2009, 47: 440-448. 10.1016/j.freeradbiomed.2009.05.016.
Article
CAS
PubMed
Google Scholar
van Eeghen AM, Black ME, Pulsifer MB, Kwiatkowski DJ, Thiele EA: Genotype and cognitive phenotype of patients with tuberous sclerosis complex. Eur J Hum Genet. 2012, 20: 510-515. 10.1038/ejhg.2011.241.
Article
PubMed Central
CAS
PubMed
Google Scholar