Skip to main content

Articles

Page 59 of 85

  1. DNA topoisomerase IIβ (topo IIβ) is known to regulate neural differentiation by inducing the neuronal genes responsible for critical neural differentiation events such as neurite outgrowth and axon guidance. H...

    Authors: Merve Zaim and Sevim Isik
    Citation: Stem Cell Research & Therapy 2018 9:114
    Content type: Research Published on:

  2. The production of veritable in-vitro models of bone tissue is essential to understand the biology of bone and its surrounding environment, to analyze the pathogenesis of bone diseases (e.g., osteoporosis, oste...

    Authors: Alessandro Pirosa, Riccardo Gottardi, Peter G. Alexander and Rocky S. Tuan
    Citation: Stem Cell Research & Therapy 2018 9:112
    Content type: Review Published on:

  3. The original article [1] mistakenly omitted a source of funding, and the authors would like to rectify this by acknowledging the additional support of the Natural Science Foundation in Jiangsu Province (BK2015...

    Authors: Zhaoyu Lin, Fei Liu, Peiliang Shi, Anying Song, Zan Huang, Dayuan Zou, Qin Chen, Jianxin Li and Xiang Gao
    Citation: Stem Cell Research & Therapy 2018 9:111
    Content type: Correction Published on:

    The original article was published in Stem Cell Research & Therapy 2018 9:47

  4. Silicosis has been topping the list of high-incidence occupational diseases in developing countries and cannot be completely cured. Recent advances in stem cell research have made possible the treatment of var...

    Authors: Shangya Chen, Guanqun Cui, Cheng Peng, Martin F. Lavin, Xiaoying Sun, Enguo Zhang, Ye Yang, Yingjun Guan, Zhongjun Du and Hua Shao
    Citation: Stem Cell Research & Therapy 2018 9:110
    Content type: Research Published on:

  5. Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory. The low viability and angiogenic capacity of the ...

    Authors: Jingying Hou, Lingyun Wang, Quanhua Wu, Guanghui Zheng, Huibao Long, Hao Wu, Changqing Zhou, Tianzhu Guo, Tingting Zhong, Lei Wang, Xuxiang Chen and Tong Wang
    Citation: Stem Cell Research & Therapy 2018 9:109
    Content type: Research Published on:

  6. Senolytic drugs are thought to target senescent cells and might thereby rejuvenate tissues. In fact, such compounds were suggested to increase health and lifespan in various murine aging models. So far, effect...

    Authors: Clara Grezella, Eduardo Fernandez-Rebollo, Julia Franzen, Mónica Sofia Ventura Ferreira, Fabian Beier and Wolfgang Wagner
    Citation: Stem Cell Research & Therapy 2018 9:108
    Content type: Short report Published on:

  7. Platelet-rich plasma (PRP) is an autologous blood product that contains a high concentration of several growth factors. Platelet-derived growth factor (PDGF)-BB is a potential mitogen for human adipose-derived...

    Authors: Fangyuan Lai, Natsuko Kakudo, Naoki Morimoto, Shigeru Taketani, Tomoya Hara, Takeshi Ogawa and Kenji Kusumoto
    Citation: Stem Cell Research & Therapy 2018 9:107
    Content type: Research Published on:

  8. Damage of mitochondria in the initial period of tissue injury aggravates the severity of injury. Restoration of mitochondria dysfunction and mitochondrial-based therapeutics represent a potentially effective t...

    Authors: Jingyu Wang, Heyangzi Li, Ying Yao, Tengfei Zhao, Ying-ying Chen, Yue-liang Shen, Lin-lin Wang and Yongjian Zhu
    Citation: Stem Cell Research & Therapy 2018 9:106
    Content type: Review Published on:

  9. The fibrocyte, which was first described in 1994, is a type of circulating mesenchymal progenitor cell in the peripheral blood. Fibrocytes play important roles in chronic inflammation, wound healing, tissue re...

    Authors: Feng Zhang, Ke Liu, Han Zhao and Yan He
    Citation: Stem Cell Research & Therapy 2018 9:105
    Content type: Review Published on:

  10. The role of bone tissue engineering in the field of regenerative medicine has been a main research topic over the past few years. There has been much interest in the use of three-dimensional (3D) engineered sc...

    Authors: Francesca Diomede, Agnese Gugliandolo, Paolo Cardelli, Ilaria Merciaro, Valeria Ettorre, Tonino Traini, Rossella Bedini, Domenico Scionti, Alessia Bramanti, Antonio Nanci, Sergio Caputi, Antonella Fontana, Emanuela Mazzon and Oriana Trubiani
    Citation: Stem Cell Research & Therapy 2018 9:104
    Content type: Research Published on:

  11. Understanding stem cell behavior as a delivery tool in cancer therapy is essential for evaluating their future clinical potential. Previous in-vivo studies proved the use of mesenchymal stem cells (MSCs) for l...

    Authors: Hamideh Salehi, Siham Al-Arag, Elodie Middendorp, Csilla Gergely, Frederic Cuisinier and Valerie Orti
    Citation: Stem Cell Research & Therapy 2018 9:103
    Content type: Research Published on:

  12. Human decidua parietalis mesenchymal stem/multipotent stromal cells (DPMSCs) have unique phenotypic and functional properties that make them promising candidates for cell-based therapy. Here, we investigated DPMS...

    Authors: M. H. Abumaree, E. Bahattab, A. Alsadoun, A. Al Dosaimani, F. M. Abomaray, T. Khatlani, B. Kalionis, M. F. El-Muzaini, A. O. Alawad and A. S. AlAskar
    Citation: Stem Cell Research & Therapy 2018 9:102
    Content type: Research Published on:

  13. White smoke inhalation (WSI) is an uncommon but potentially deadly cause of acute lung injury and acute respiratory distress syndrome for which no effective pharmaceutical treatment has been developed. This st...

    Authors: Pei Cui, Haiming Xin, Yongming Yao, Shichu Xiao, Feng Zhu, Zhenyu Gong, Zhiping Tang, Qiu Zhan, Wei Qin, Yanhua Lai, Xiaohui Li, Yalin Tong and Zhaofan Xia
    Citation: Stem Cell Research & Therapy 2018 9:101
    Content type: Research Published on:

  14. With the development of osteoimmunology and bone tissue engineering (BTE), it has been recognized that the immunomodulatory properties of bone biomaterials have considerable impact in determining their fate af...

    Authors: Tao Li, Zhong Long Liu, Ming Xiao, Ze Zheng Yang, Ming Zheng Peng, Cui Di Li, Xiao Jun Zhou and Jin Wu Wang
    Citation: Stem Cell Research & Therapy 2018 9:100
    Content type: Research Published on:

  15. Bullosis diabeticorum is a rare presentation of cutaneous manifestation most commonly affecting the lower limbs in patients with diabetes. The appearance, often as insidious as its resolution, is characterized...

    Authors: Yan Chen, Yu Ma, Ning Li, Hongyan Wang, Bing Chen, Ziwen Liang, Rui Ren, Debin Lu, Johnson Boey, David G. Armstrong and Wuquan Deng
    Citation: Stem Cell Research & Therapy 2018 9:99
    Content type: Short report Published on:

  16. Nicotine has negative effects on tissue repair, little research concerns its effect on the cartilage repair of tissue engineering stem cells. The present study aimed to investigate the effects of nicotine on t...

    Authors: Kai Tie, Min Wu, Yu Deng, Yinxian Wen, Dan Xu, Liaobin Chen and Hui Wang
    Citation: Stem Cell Research & Therapy 2018 9:98
    Content type: Research Published on:

  17. Commitment of pluripotent stem cells into differentiated cells and associated gene expression necessitate specific epigenetic mechanisms that modify the DNA and corresponding histone proteins to render the chr...

    Authors: Varsha Pursani, Deepa Bhartiya, Vivek Tanavde, Mohsin Bashir and Prabha Sampath
    Citation: Stem Cell Research & Therapy 2018 9:97
    Content type: Research Published on:

  18. It is currently unknown if the intrathecal administration of a high dose of allogeneic mesenchymal stem cells (MSCs) is safe, how MSCs migrate throughout the vertebral canal after intrathecal administration, a...

    Authors: Danielle Jaqueta Barberini, Monica Aleman, Fabio Aristizabal, Mathieu Spriet, Kaitlin C. Clark, Naomi J. Walker, Larry D. Galuppo, Rogério Martins Amorim, Kevin D. Woolard and Dori L. Borjesson
    Citation: Stem Cell Research & Therapy 2018 9:96
    Content type: Research Published on:

  19. Mesenchymal stem cells have potential applications in inflammatory bowel disease due to their immunomodulatory properties. Our aim was to evaluate the feasibility, safety and efficacy of endoscopic administrat...

    Authors: Eduardo Martín Arranz, María Dolores Martín Arranz, Tomás Robredo, Pablo Mancheño-Corvo, Ramón Menta, Francisco Javier Alves, Jose Manuel Suárez de Parga, Pedro Mora Sanz, Olga de la Rosa, Dirk Büscher, Eleuterio Lombardo and Fernando de Miguel
    Citation: Stem Cell Research & Therapy 2018 9:95
    Content type: Research Published on:

  20. Upon orthognathic mandibular advancement surgery the adjacent soft tissues can displace the distal bone segment and increase the load on the temporomandibular joint causing loss of its integrity. Remodeling of...

    Authors: Ricardo de Souza Tesch, Esther Rieko Takamori, Karla Menezes, Rosana Bizon Vieira Carias, Cláudio Leonardo Milione Dutra, Marcelo de Freitas Aguiar, Tânia Salgado de Sousa Torraca, Alexandra Cristina Senegaglia, Cármen Lúcia Kuniyoshi Rebelatto, Debora Regina Daga, Paulo Roberto Slud Brofman and Radovan Borojevic
    Citation: Stem Cell Research & Therapy 2018 9:94
    Content type: Research Published on:

  21. Mesenchymal stem cells (MSCs) are multipotent cells holding much promise for applications in regenerative medicine. However, with problems such as aging, increases in heteroploid cells, genomic instability, an...

    Authors: Koichi Fujisawa, Kazusa Hara, Taro Takami, Sae Okada, Toshihiko Matsumoto, Naoki Yamamoto and Isao Sakaida
    Citation: Stem Cell Research & Therapy 2018 9:93
    Content type: Research Published on:

  22. Replacement therapy for hemophilia remains a lifelong treatment. Only gene therapy can cure hemophilia at a fundamental level. The clustered regularly interspaced short palindromic repeats–CRISPR associated nu...

    Authors: Cuicui Lyu, Jun Shen, Rui Wang, Haihui Gu, Jianping Zhang, Feng Xue, Xiaofan Liu, Wei Liu, Rongfeng Fu, Liyan Zhang, Huiyuan Li, Xiaobing Zhang, Tao Cheng, Renchi Yang and Lei Zhang
    Citation: Stem Cell Research & Therapy 2018 9:92
    Content type: Research Published on:

  23. Inflammatory bowel disease (IBD) is an intractable autoimmune disorder that markedly deteriorates one’s quality of life. Mesenchymal stem cells (MSCs) alleviate inflammation by modulating inflammatory cytokine...

    Authors: Woo-Jin Song, Qiang Li, Min-Ok Ryu, Jin-Ok Ahn, Dong Ha Bhang, Yun Chan Jung and Hwa-Young Youn
    Citation: Stem Cell Research & Therapy 2018 9:91
    Content type: Research Published on:

  24. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive muscle weakness, paralysis and death. There is no effective treatment for ALS and stem cell therapy has arisen a...

    Authors: Amaya Rando, Diego Pastor, Mari Carmen Viso-León, Anna Martínez, Raquel Manzano, Xavier Navarro, Rosario Osta and Salvador Martínez
    Citation: Stem Cell Research & Therapy 2018 9:90
    Content type: Research Published on:

  25. The Th1 cell-specific transcription factor TBX21 functions as a regulator of expression of a Th1 cytokine, interferon gamma (IFN-γ). However, the specific function of TBX21 correlated with cancer stemness rema...

    Authors: Shuangtao Zhao, Wenzhi Shen, Jiangyong Yu and Luhua Wang
    Citation: Stem Cell Research & Therapy 2018 9:89
    Content type: Research Published on:

  26. Skeletal muscle plays an important role in the body’s physiology but there are still no effective treatments for volumetric muscle loss (VML) resulting from severe traumatic injury or tumor excision. Recent st...

    Authors: Xinyu Qiu, Shiyu Liu, Hao Zhang, Bin Zhu, Yuting Su, Chenxi Zheng, Rong Tian, Miao Wang, Huijuan Kuang, Xinyi Zhao and Yan Jin
    Citation: Stem Cell Research & Therapy 2018 9:88
    Content type: Research Published on:

  28. Adult mesenchymal stem cells (MSCs) are an important resource for tissue growth, repair, and regeneration. To utilize MSCs more effectively, a clear understanding of how they react to environmental cues is ess...

    Authors: Jihee Sohn, Hang Lin, Madalyn Rose Fritch and Rocky S. Tuan
    Citation: Stem Cell Research & Therapy 2018 9:86
    Content type: Research Published on:

  29. Mesenchymal stem cell (MSC) transplantation shows promise for treating transplant arteriosclerosis, at least partly via promoting endothelial regeneration. However, the efficacy and safety are still under inve...

    Authors: Xiaohu Meng, Min Chen, Wenjie Su, Xuan Tao, Mingyang Sun, Xiaoping Zou, Rongchao Ying, Wei Wei and Baolin Wang
    Citation: Stem Cell Research & Therapy 2018 9:85
    Content type: Research Published on:

  30. Despite the significant progress in the development of skin equivalents (SEs), the problem of noninvasively assessing the quality of the cell components and the collagen structure of living SEs both before and...

    Authors: Aleksandra V. Meleshina, Olga S. Rogovaya, Varvara V. Dudenkova, Marina A. Sirotkina, Maria M. Lukina, Alena S. Bystrova, Victoria G. Krut, Daria S. Kuznetsova, Ekaterina P. Kalabusheva, Andrey V. Vasiliev, Ekaterina A. Vorotelyak and Elena V. Zagaynova
    Citation: Stem Cell Research & Therapy 2018 9:84
    Content type: Research Published on:

  31. The expression of a specific combination of transcription factors (TFs) in the multipotent progenitor cells (MPCs) is critical for determining pancreatic cell fate. NKX6.1 expression in PDX1+ MPCs is required for...

    Authors: Idil I. Aigha, Bushra Memon, Ahmed K. Elsayed and Essam M. Abdelalim
    Citation: Stem Cell Research & Therapy 2018 9:83
    Content type: Research Published on:

  32. Inflammatory licensed mesenchymal stem cells (MSCs) have the ability to promote functional tissue repair. This study specifically sought to understand how the recipient tissue environment reciprocally affects ...

    Authors: Jennifer M. Cassano, Lauren V. Schnabel, Margaret B. Goodale and Lisa A. Fortier
    Citation: Stem Cell Research & Therapy 2018 9:82
    Content type: Research Published on:

  33. Previous studies have reported that transplantation of mesenchymal stem cells (MSCs) from many human tissues could ameliorate ovarian dysfunction. However, no study has revealed the therapeutic efficiency of M...

    Authors: Jun Li, Qingtong Yu, Haisen Huang, Wenwen Deng, Xia Cao, Michael Adu-Frimpong, Jiangnan Yu and Ximing Xu
    Citation: Stem Cell Research & Therapy 2018 9:81
    Content type: Research Published on:

  34. Latent microorganism infection is a safety concern for the clinical application of mesenchymal stem cells (MSCs). The aim of this study is to investigate the frequencies and sensitivities of the latent virus a...

    Authors: Ken Watanabe, Koji Otabe, Norio Shimizu, Keiichirou Komori, Mitsuru Mizuno, Hisako Katano, Hideyuki Koga and Ichiro Sekiya
    Citation: Stem Cell Research & Therapy 2018 9:80
    Content type: Research Published on:

  35. In the bone tissue engineering domain, seed cells, scaffold and cell-scaffold composites are three focuses. In this study, the feasibility of using allogeneic adipose-derived stem cells(ADSCs) combined with he...

    Authors: Jia Liu, Peng Zhou, Yu Long, Chunxia Huang and Danna Chen
    Citation: Stem Cell Research & Therapy 2018 9:79
    Content type: Research Published on:

  37. The marrow microenvironment and vasculature plays a critical role in regulating hematopoietic cell recruitment, residence, and maturation. Extensive in vitro and in vivo studies have aimed to understand the marro...

    Authors: Surya S. Kotha, Brian J. Hayes, Kiet T. Phong, Meredith A. Redd, Karol Bomsztyk, Aravind Ramakrishnan, Beverly Torok-Storb and Ying Zheng
    Citation: Stem Cell Research & Therapy 2018 9:77
    Content type: Research Published on:

  38. The original article [1] contains an error whereby the corresponding authorship is mistakenly designated to the author Fengxia Ding.

    Authors: Bo Liu, Fengxia Ding, Dong Hu, Yu Zhou, Chunlan Long, Lianju Shen, Yuanyuan Zhang, Deying Zhang and Guanghui Wei
    Citation: Stem Cell Research & Therapy 2018 9:76
    Content type: Correction Published on:

    The original article was published in Stem Cell Research & Therapy 2018 9:7

  39. Mesenchymal stem cells (MSCs) produced for clinical purposes rely on culture media containing fetal bovine serum (FBS) which is xenogeneic and has the potential to significantly alter the MSC phenotype, render...

    Authors: Maria C. Naskou, Scarlett M. Sumner, Anna Chocallo, Hannah Kemelmakher, Merrilee Thoresen, Ian Copland, Jacques Galipeau and John F. Peroni
    Citation: Stem Cell Research & Therapy 2018 9:75
    Content type: Research Published on:

  40. Three-dimensional (3D) cultures recapitulate the microenvironment of tissue-resident stem cells and enable them to modulate their properties. We determined whether salivary gland-resident stem cells (SGSCs) ar...

    Authors: Hyun-Soo Shin, Songyi Lee, Hye Jin Hong, Young Chang Lim, Won-Gun Koh and Jae-Yol Lim
    Citation: Stem Cell Research & Therapy 2018 9:74
    Content type: Research Published on:

  41. Three-dimensional (3D) cultured clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and self-produced ECM. C-MSCs can regulate cellular functions in vitro and c...

    Authors: Souta Motoike, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Susumu Horikoshi, Shinji Matsuda, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Tsuyoshi Fujita and Hidemi Kurihara
    Citation: Stem Cell Research & Therapy 2018 9:73
    Content type: Research Published on:

  44. Induced pluripotent stem-cell derived endothelial cells (iPSC-ECs) can be generated from any somatic cell and their iPSC sources possess unlimited self-renewal. Previous demonstration of their proangiogenic ac...

    Authors: Richard P. Tan, Alex H. P. Chan, Katarina Lennartsson, Maria M. Miravet, Bob S. L. Lee, Jelena Rnjak-Kovacina, Zoe E. Clayton, John P. Cooke, Martin K. C. Ng, Sanjay Patel and Steven G. Wise
    Citation: Stem Cell Research & Therapy 2018 9:70
    Content type: Research Published on:

  46. While a shift towards non-viral and animal component-free methods of generating induced pluripotent stem (iPS) cells is preferred for safer clinical applications, there is still a shortage of reliable cell sou...

    Authors: Srijaya Thekkeparambil Chandrabose, Sandhya Sriram, Subha Subramanian, Shanshan Cheng, Wee Kiat Ong, Steve Rozen, Noor Hayaty Abu Kasim and Shigeki Sugii
    Citation: Stem Cell Research & Therapy 2018 9:68
    Content type: Research Published on:

  47. Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been widely used to generate cellular models harboring specific disease-related genotypes. Of particular importance are ESC and iPSC ...

    Authors: Meixiang Zhang, Justine Ngo, Filomena Pirozzi, Ying-Pu Sun and Anthony Wynshaw-Boris
    Citation: Stem Cell Research & Therapy 2018 9:67
    Content type: Method Published on:

  48. Scarring is the product of natural restoration, yet its treatment remains challenging. Both collagen and fibroblasts are abnormally abundant in scars, leading to scar hyperplasia or contracture. Several clinic...

    Authors: Xiao Xu, Linying Lai, Xuyi Zhang, Jinhong Chen, Junnan Chen, Fei Wang, Jingchen Zheng and Minliang Chen
    Citation: Stem Cell Research & Therapy 2018 9:64
    Content type: Research Published on:

  50. Circular RNAs (circRNAs) are regarded as a novel class of noncoding RNA regulators. Although a number of circRNAs have been identified by bioinformatics analysis of RNA-seq data, tissue and disease-specific ci...

    Authors: Wei Lei, Tingting Feng, Xing Fang, You Yu, Junjie Yang, Zhen-Ao Zhao, Junwei Liu, Zhenya Shen, Wenbo Deng and Shijun Hu
    Citation: Stem Cell Research & Therapy 2018 9:56
    Content type: Research Published on:
Submit manuscript

Follow

Annual Journal Metrics

  • 2022 Citation Impact
    7.5 - 2-year Impact Factor
    8.0 - 5-year Impact Factor
    1.440 - SNIP (Source Normalized Impact per Paper)
    1.498 - SJR (SCImago Journal Rank)

    2023 Speed
    33 days submission to first editorial decision for all manuscripts (Median)
    211 days submission to accept (Median)

    2023 Usage 
    3,320,811 downloads
    1,402 Altmetric mentions

Stem Cell Research & Therapy

ISSN: 1757-6512