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  1. The functions of HULC have been demonstrated in several cancers. However, its mechanism has not been elucidated in human liver cancer stem cells.

    Authors: Chen Wang, Xiaoxue Jiang, Xiaonan Li, Shuting Song, Qiuyu Meng, Liyan Wang, Yanan Lu, Xiaoru Xin, Hu Pu, Xin Gui, Tianming Li and Dongdong Lu
    Citation: Stem Cell Research & Therapy 2020 11:8
    Content type: Research Published on:

  3. Therapy-associated onset of stemness-maintenance in surviving tumor-cells dictates tumor relapse/recurrence. Recently, we recognized the anti-pancreatic cancer (PC) potential of seaweed polyphenol manifolds an...

    Authors: Sheeja Aravindan, Satish Kumar Ramraj, Somasundaram T. Somasundaram, Terence S. Herman and Natarajan Aravindan
    Citation: Stem Cell Research & Therapy 2015 6:182
    Content type: Research Published on:

  4. Accumulated evidence supports the potent stimulating effects of multiple small molecules on the expansion of hematopoietic stem cells (HSCs) which are important for the therapy of various hematological disorde...

    Authors: Lan Wang, Xin Guan, Huihui Wang, Bin Shen, Yu Zhang, Zhihua Ren, Yupo Ma, Xinxin Ding and Yongping Jiang
    Citation: Stem Cell Research & Therapy 2017 8:169
    Content type: Research Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2021 12:458

  6. Regenerative medicine potentially offers the opportunity for curing male infertility. Native extracellular matrix (ECM) creates a reconstruction platform to replace the organs. In this study, we aimed to evalu...

    Authors: Elias Kargar-Abarghouei, Zahra Vojdani, Ashraf Hassanpour, Sanaz Alaee and Tahereh Talaei-Khozani
    Citation: Stem Cell Research & Therapy 2018 9:324
    Content type: Research Published on:

  7. Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered attractive sources of pancreatic β cells and islet organoids. Recently, several reports presented that hESC/iPSC-deri...

    Authors: Hussain Md. Shahjalal, Ahmed Abdal Dayem, Kyung Min Lim, Tak-il Jeon and Ssang-Goo Cho
    Citation: Stem Cell Research & Therapy 2018 9:355
    Content type: Review Published on:

  8. Our group has developed a novel method for spontaneous spheroid formation using a specific low-adherence culture plate with around 90° water contact angle. In this study, this method was applied for oral mucos...

    Authors: Ni Li, Xianqi Li, Kai Chen, Hongwei Dong and Hideaki Kagami
    Citation: Stem Cell Research & Therapy 2019 10:184
    Content type: Research Published on:

  9. Stem cell therapy can be used for alleviating the neuropathic pain induced by spinal cord injuries (SCIs). However, survival and differentiation of stem cells following their transplantation vary depending on ...

    Authors: Mahmoud Yousefifard, Farinaz Nasirinezhad, Homa Shardi Manaheji, Atousa Janzadeh, Mostafa Hosseini and Mansoor Keshavarz
    Citation: Stem Cell Research & Therapy 2016 7:36
    Content type: Research Published on:

  10. Mesenchymal stem cells (MSCs) play a crucial role in maintaining the dynamic balance of bone metabolism. Melatonin may have a regulatory effect on bone metabolism by regulating the lineage commitment and diffe...

    Authors: Tianyuan Jiang, Chao Xia, Xiaoting Chen, Yan Hu, Yan Wang, Jin Wu, Shuyan Chen and Yanhong Gao
    Citation: Stem Cell Research & Therapy 2019 10:408
    Content type: Research Published on:

  12. Bone marrow mesenchymal stem cells (MSCs) are promising candidates for the treatment of various inflammatory disorders due to their profound immunomodulatory properties. However, the immunosuppressive capacity...

    Authors: Binsheng Wang, Yu Lin, Yongxian Hu, Wei Shan, Senquan Liu, Yulin Xu, Hao Zhang, Shuyang Cai, Xiaohong Yu, Zhen Cai and He Huang
    Citation: Stem Cell Research & Therapy 2017 8:292
    Content type: Research Published on:

  13. Acute liver failure (ALF) is a complicated clinical syndrome associated with high mortality, with liver transplantation as the only treatment option. Treatment of mesenchymal stem cells has shown a potential t...

    Authors: Gang Guo, Xiang Zhuang, Qing Xu, Zhenru Wu, Yongjie Zhu, Yongjie Zhou, Yuanmin Li, Yanrong Lu, Bo Zhang, Prue Talbot, Jiayu Liao, Junjun She, Hong Bu and Yujun Shi
    Citation: Stem Cell Research & Therapy 2019 10:84
    Content type: Research Published on:

  14. Tooth agenesis, one of the most common developmental anomalies, can affect the function and esthetics of patients. The aim of the present study was to identify genetic clues for familial tooth agenesis and exp...

    Authors: Tianyi Xin, Ting Zhang, Qian Li, Tingting Yu, Yunyan Zhu, Ruili Yang and Yanheng Zhou
    Citation: Stem Cell Research & Therapy 2018 9:221
    Content type: Research Published on:

  16. Heart failure has become a global health problem with increasing incidences worldwide. Traditional pharmacological treatments can delay but cannot reverse the underlying disease processes. The clinical applica...

    Authors: Fei Zhang, Yuan Xie and Yuhao Bian
    Citation: Stem Cell Research & Therapy 2018 9:358
    Content type: Research Published on:

  17. Human induced pluripotent stem cells (iPSCs) have been verified as a powerful cell model for the study of pathogenesis in hereditary disease. Autosomal dominant polycystic kidney disease (ADPKD) is caused by m...

    Authors: Jiahui Huang, Shumin Zhou, Xin Niu, Bin Hu, Qing Li, Feng Zhang, Xue Zhang, Xiujuan Cai, Yuanlei Lou, Fen Liu, Chenming Xu and Yang Wang
    Citation: Stem Cell Research & Therapy 2017 8:196
    Content type: Research Published on:

  18. Equine mesenchymal stromal/stem cells (MSCs) are most commonly harvested from bone marrow (BM) or adipose tissue, requiring the use of surgical procedures. By contrast, the uterus can be accessed nonsurgically...

    Authors: B. Elisabeth Rink, Karin R. Amilon, Cristina L. Esteves, Hilari M. French, Elaine Watson, Christine Aurich and F. Xavier Donadeu
    Citation: Stem Cell Research & Therapy 2017 8:166
    Content type: Research Published on:

  19. Due to their extensive self-renewal and multilineage differentiation capacity, human embryonic stem cells (hESCs) have great potential for studying developmental biology, disease modeling, and developing cell ...

    Authors: Chuti Laowtammathron, Pimjai Chingsuwanrote, Roungsin Choavaratana, Suphadtra Phornwilardsiri, Ketsara Sitthirit, Chidchanok Kaewjunun, Orawan Makemaharn, Papussorn Terbto, Supaporn Waeteekul, Chanchao Lorthongpanich, Yaowalak U-pratya, Pimonwan Srisook, Pakpoom Kheolamai and Surapol Issaragrisil
    Citation: Stem Cell Research & Therapy 2018 9:138
    Content type: Research Published on:

  20. Pluripotent stem cells (PSCs) such as embryonic stem cells and induced pluripotent stem cells are promising target cells for cell regenerative medicine together with recently advanced technology of in-vitro di...

    Authors: Seok-Jin Kang, Young-Il Park, So-Ryeon Hwang, Hee Yi, Nga Tham, Hyun-Ok Ku, Jae-Young Song and Hwan-Goo Kang
    Citation: Stem Cell Research & Therapy 2017 8:78
    Content type: Research Published on:

  21. Skeletal muscle regeneration is possible thanks to unipotent stem cells, which are satellite cells connected to the myofibers. Populations of stem cells other than muscle-specific satellite cells are considere...

    Authors: Kamil Kowalski, Matthieu Dos Santos, Pascal Maire, Maria A. Ciemerych and Edyta Brzoska
    Citation: Stem Cell Research & Therapy 2018 9:258
    Content type: Research Published on:

  22. Odontoblasts are cells that contribute to the formation of the dental pulp complex. The differentiation of dental tissue-derived mesenchymal stem cells into odontoblasts comprises many factors and signaling pa...

    Authors: Fuchun Fang, Kaiying Zhang, Zhao Chen and Buling Wu
    Citation: Stem Cell Research & Therapy 2019 10:297
    Content type: Review Published on:

  23. Spinal cord injury (SCI) results in glial scar formation and irreversible neuronal loss, which finally leads to functional impairments and long-term disability. Our previous studies have demonstrated that the ...

    Authors: Masoumeh Zarei-Kheirabadi, Mahdi Hesaraki, Sahar Kiani and Hossein Baharvand
    Citation: Stem Cell Research & Therapy 2019 10:380
    Content type: Research Published on:

  24. Sepsis is a clinical syndrome associated with a severe systemic inflammation induced by infection. Although different anti-microbial drugs have been used as treatments, morbidity and mortality rates remain hig...

    Authors: Francisca Alcayaga-Miranda, Jimena Cuenca, Aldo Martin, Luis Contreras, Fernando E. Figueroa and Maroun Khoury
    Citation: Stem Cell Research & Therapy 2015 6:199
    Content type: Research Published on:

  25. The skin has important barrier, sensory, and immune functions, contributing to the health and integrity of the organism. Extensive skin injuries that threaten the entire organism require immediate and effectiv...

    Authors: Ronghua Yang, Fengxia Liu, Jingru Wang, Xiaodong Chen, Julin Xie and Kun Xiong
    Citation: Stem Cell Research & Therapy 2019 10:229
    Content type: Review Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2020 11:447

  26. A dynamic interaction between tumor cells and its surrounding stroma promotes the initiation, progression, metastasis, and chemoresistance of solid tumors. Emerging evidences suggest that targeting the stromal...

    Authors: Tithi Ghosh, Partha Nandi, Nilanjan Ganguly, Ipsita Guha, Avishek Bhuniya, Sarbari Ghosh, Anirban Sarkar, Akata Saha, Shayani Dasgupta, Rathindranath Baral and Anamika Bose
    Citation: Stem Cell Research & Therapy 2019 10:296
    Content type: Research Published on:

  27. Bone marrow-derived mesenchymal stem cells (BMSCs) are gradually getting attention because of its multi-directional differentiation potential, hematopoietic support, and promotion of stem cell implantation. Ho...

    Authors: Lihong Wang, Xianjing Han, Guojing Qu, Le Su, Baoxiang Zhao and Junying Miao
    Citation: Stem Cell Research & Therapy 2018 9:343
    Content type: Research Published on:

  28. Malaria is the most relevant parasitic disease worldwide, and still accounts for 1 million deaths each year. Since current antimalarial drugs are unable to prevent death in severe cases, new therapeutic strate...

    Authors: Mariana C Souza, Johnatas D Silva, Tatiana A Pádua, Natália D Torres, Mariana A Antunes, Debora G Xisto, Thiago P Abreu, Vera L Capelozzi, Marcelo M Morales, Ana A. Sá Pinheiro, Celso Caruso-Neves, Maria G Henriques and Patricia RM Rocco
    Citation: Stem Cell Research & Therapy 2015 6:102
    Content type: Research Published on:

  29. In the field of experimental stem cell therapy, intra-arterial (IA) delivery yields the best results concerning, for example, migrated cell number at the targeted site. However, IA application also appears to ...

    Authors: Saskia Grudzenski, Sebastian Baier, Anne Ebert, Pim Pullens, Andreas Lemke, Karen Bieback, Rick M. Dijkhuizen, Lothar R. Schad, Angelika Alonso, Michael G. Hennerici and Marc Fatar
    Citation: Stem Cell Research & Therapy 2017 8:96
    Content type: Research Published on:

  30. Extracellular vesicles (EVs), especially stem cell-derived EVs, have emerged as a potential novel therapy for acute kidney injury (AKI). However, their effects remain incompletely understood. Therefore, we per...

    Authors: Chao Liu, Jin Wang, Jie Hu, Bo Fu, Zhi Mao, Hengda Zhang, Guangyan Cai, Xiangmei Chen and Xuefeng Sun
    Citation: Stem Cell Research & Therapy 2020 11:11
    Content type: Research Published on:

  31. Radiation-induced gastrointestinal syndrome (RIGS) results from the acute loss of intestinal stem cells (ISC), impaired epithelial regeneration, and subsequent loss of the mucosal barrier, resulting in electro...

    Authors: Payel Bhanja, Andrew Norris, Pooja Gupta-Saraf, Andrew Hoover and Subhrajit Saha
    Citation: Stem Cell Research & Therapy 2018 9:26
    Content type: Research Published on:

  32. Mesenchymal stem/stromal cells derived from chorionic villi of human term placentae (pMSCs) protect human endothelial cells from injury induced by hydrogen peroxide (H2O2). In diabetes, elevated levels of glucose...

    Authors: Y. S. Basmaeil, A. M. Al Subayyil, T. Khatlani, E. Bahattab, M. Al-Alwan, F. M. Abomaray, B. Kalionis, M. A. Alshabibi, A. S. AlAskar and M. H. Abumaree
    Citation: Stem Cell Research & Therapy 2018 9:238
    Content type: Research Published on:

  33. In most stem cell therapy strategies reported to date, stem cells are introduced to damaged tissue sites to repair and regenerate the original tissue structure and function. MSC therapeutic efficacies are inco...

    Authors: Mitsuyoshi Nakao, Kyungsook Kim, Kenichi Nagase, David W. Grainger, Hideko Kanazawa and Teruo Okano
    Citation: Stem Cell Research & Therapy 2019 10:353
    Content type: Research Published on:

  34. Extracellular vesicles (EVs) are cellular-derived versatile transporters with a specialized property for trafficking a variety of cargo, including metabolites, growth factors, cytokines, proteins, lipids, and ...

    Authors: Mujib Ullah, Yang Qiao, Waldo Concepcion and Avnesh S. Thakor
    Citation: Stem Cell Research & Therapy 2019 10:347
    Content type: Review Published on:

  35. Tid1 is a mitochondrial co-chaperone protein and its transcript is abundantly expressed in skeletal muscle tissues. However, the physiological function of Tid1 during skeletal myogenesis remains unclear.

    Authors: Li-Hao Cheng, Kai-Feng Hung, Te-Chang Lee, Chih-Yang Huang, Wen-Ting Chiu, Jeng-Fan Lo and Tung-Fu Huang
    Citation: Stem Cell Research & Therapy 2016 7:185
    Content type: Research Published on:

  36. Newcastle disease virus (NDV) is an avian paramyxovirus, which selectively exerts oncolytic effects in cancer cells. Mesenchymal stem cells (MSCs) have been reported to affect tumor growth and deliver anti-tum...

    Authors: Gila Kazimirsky, Wei Jiang, Shimon Slavin, Amotz Ziv-Av and Chaya Brodie
    Citation: Stem Cell Research & Therapy 2016 7:149
    Content type: Research Published on:

  37. The main goal of bone tissue engineering has been the generation of healthy bone in order to replace affected tissue. Therefore, optimized biomaterials are needed which allow the survival and growth of mesench...

    Authors: Anastasia Gabrielyan, Elena Neumann, Michael Gelinsky and Angela Rösen-Wolff
    Citation: Stem Cell Research & Therapy 2017 8:212
    Content type: Research Published on:

  38. Human mesenchymal stem cells are a strong candidate for cell therapies owing to their regenerative potential, paracrine regulatory effects, and immunomodulatory activity. Yet, their scarcity, limited expansion...

    Authors: Madison McGrath, Edmund Tam, Martina Sladkova, Athbah AlManaie, Matthew Zimmer and Giuseppe Maria de Peppo
    Citation: Stem Cell Research & Therapy 2019 10:11
    Content type: Research Published on:

  39. Intrauterine adhesion (IUA) is one of the most serious complications in patients with endometrial repair disorder after injury. Currently, there is no effective treatment for IUA. Stem cell is the main candida...

    Authors: Yuan Yao, Ran Chen, Guowu Wang, Yu Zhang and Fang Liu
    Citation: Stem Cell Research & Therapy 2019 10:225
    Content type: Research Published on:

  40. Autosomal dominant osteopetrosis type II (ADO2) is a rare human genetic disease that has been broadly studied as an important osteopetrosis model; however, there are no disease-specific induced pluripotent ste...

    Authors: Minglin Ou, Chunhong Li, Donge Tang, Wen Xue, Yong Xu, Peng Zhu, Bo Li, Jiansheng Xie, Jiejing Chen, Weiguo Sui, Lianghong Yin and Yong Dai
    Citation: Stem Cell Research & Therapy 2019 10:251
    Content type: Research Published on:
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