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  1. Immunologically impaired individuals respond poorly to vaccines, highlighting the need for additional strategies to protect these vulnerable populations from COVID-19. While monoclonal antibodies (mAbs) have e...

    Authors: Evan Sawula, Shane Miersch, Eric D. Jong, Chengjin Li, Fang-Yu Chou, Jean Kit Tang, Reza Saberianfar, Jeffrey Harding, Sachdev S. Sidhu and Andras Nagy
    Citation: Stem Cell Research & Therapy 2023 14:318
  2. Autoimmune hepatitis (AIH) is a T-cell-mediated autoimmune liver disease that can lead to liver injury and has a poor long-term prognosis. Mesenchymal stromal cells (MSCs) have immunosuppressive effects and ca...

    Authors: Wenbin Ji, Weiwei Wang, Peiyuan Li, Yanhong Liu, Baotong Zhang and Feng Qi
    Citation: Stem Cell Research & Therapy 2023 14:316
  3. Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are used in regenerative medicine and related research involving immunomodulatory, anti-inflammatory, anti-fibrotic and regenerative functions. Isolation...

    Authors: Maximilian Handke, Anastasia Rakow, Debora Singer, Lea Miebach, Frank Schulze, Sander Bekeschus, Janosch Schoon and Georgi I. Wassilew
    Citation: Stem Cell Research & Therapy 2023 14:315
  4. Human pluripotent stem cell (hPSC)-derived hepatocyte-like cells (HLCs) can provide a valuable in vitro model for disease modelling and drug development. However, generating HLCs with characteristics comparabl...

    Authors: Faiza Farhan, Manjari Trivedi, Priscilla Di Wu and Wei Cui
    Citation: Stem Cell Research & Therapy 2023 14:314
  5. Prolonged air leak (PAL) is the most frequent complication after pulmonary resection. Several measures have been described to prevent the occurrence of PAL in high-risk patients, however, the potential role of...

    Authors: Marcelo F. Jiménez, María Teresa Gómez-Hernández, Eva M. Villarón, Miriam López-Parra and Fermín Sánchez-Guijo
    Citation: Stem Cell Research & Therapy 2023 14:313
  6. Thymic epithelial cells (TECs) are responsible for shaping the repertoires of T cells, where their postnatal regeneration depends on a subset of clonogenic TECs. Despite the implications for regenerative medic...

    Authors: Juan M. Ocampo-Godinez, Jose L. Gonzalez-Quiroz, Hector Cote-Palafox, Elizabeth George, Jael A. Vergara-Lope Nuñez, Guillermo Villagomez-Olea, Febe C. Vazquez-Vazquez, Edgar O. Lopez-Villegas, Gloria Leon-Avila, Maria L. Dominguez-Lopez and Marco A. Alvarez-Perez
    Citation: Stem Cell Research & Therapy 2023 14:312

    The Correction to this article has been published in Stem Cell Research & Therapy 2024 15:39

  7. The aim of the study was to evaluate the efficacy and safety of allogeneic umbilical cord-derived mesenchymal stem cells (TH-SC01) for complex perianal fistula in patients with Crohn’s disease (CD).

    Authors: Juan Wei, Yufei Zhang, Chunyan Chen, Xiaoyue Feng, Zhao Yang, Jing Feng, Qiong Jiang, Jinjin Fu, Ji Xuan, Hong Gao, Lianming Liao and Fangyu Wang
    Citation: Stem Cell Research & Therapy 2023 14:311
  8. Authors: Ruiying Wang, Min Wang, Shan Wang, Ke Yang, Ping Zhou, Xueheng Xie, Qi Cheng, Jingxue Ye, Guibo Sun and Xiaobo Sun
    Citation: Stem Cell Research & Therapy 2023 14:310

    The original article was published in Stem Cell Research & Therapy 2019 10:20

  9. Pseudoenzymes, catalytically deficient variants of active enzymes, have a wide range of regulatory functions. ADP-ribosylhydrolase-like 1 (ADPRHL1), a pseudoenzyme belonging to a small group of ADP-ribosylhydr...

    Authors: Lei Tian, Tianwei Guo, Fujian Wu, Rui Bai, Sinan Ai, Hongyue Wang, Yuanxiu Song, Min Zhu, Youxu Jiang, Shuhong Ma, Xiaofeng Zhuang and Shuzhen Guo
    Citation: Stem Cell Research & Therapy 2023 14:309
  10. Stem cell transplantation is an emerging therapy for severe cardiomyopathy, proffering stem cell recruitment, anti-apoptosis, and proangiogenic capabilities. Angiogenic cell precursors (ACP-01) are autologous,...

    Authors: Jane R. Schubart, Amirhossein Zare, Roberto M. Fernandez-de-Castro, Hector Rosario Figueroa, Ina Sarel, Kelly Tuchman, Kaitlyn Esposito, Fraser C. Henderson and Ernst von Schwarz
    Citation: Stem Cell Research & Therapy 2023 14:308
  11. Tendinopathy is a debilitating and crippling syndrome resulting from the degeneration of tendon tissue, leading to loss of mechanical properties and function, and eventual tendon rupture. Unfortunately, there ...

    Authors: Yuxiang Zhang, Wei Ju, Hong Zhang, Liu Mengyun, Weiliang Shen and Xiao Chen
    Citation: Stem Cell Research & Therapy 2023 14:307
  12. Skin tissue engineering is a rapidly evolving field of research that effectively combines stem cells and biological scaffolds to replace damaged tissues. Human Wharton’s jelly mesenchymal stromal cells (hWJ-MS...

    Authors: Luz Correa-Araujo, Leonardo Prieto-Abello, Adriana Lara-Bertrand, Martha Medina-Solano, Linda Guerrero, Bernardo Camacho and Ingrid Silva-Cote
    Citation: Stem Cell Research & Therapy 2023 14:306
  13. The therapeutic application of multipotent mesenchymal stem cells (MSCs) encounters significant challenges, primarily stemming from their inadequate growth and limited self-renewal capabilities. Additionally, ...

    Authors: Matteo Mazzella, Keegan Walker, Christina Cormier, Michael Kapanowski, Albi Ishmakej, Azeem Saifee, Yashvardhan Govind and G. Rasul Chaudhry
    Citation: Stem Cell Research & Therapy 2023 14:305
  14. Umbilical cord blood transplantation (UCBT) is a curable therapy for hematological disease; however, the impact of nutritional status on UCBT outcomes remains controversial. To evaluate the joint effect of cli...

    Authors: Meijuan Tu, Aijie Huang, Lijuan Ning, Baolin Tang, Chunli Zhang, Guangyu Sun, Xiang Wan, Kaidi Song, Wen Yao, Ping Qiang, Yue Wu and Xiaoyu Zhu
    Citation: Stem Cell Research & Therapy 2023 14:304
  15. There is growing interest to application of regenerative medicine approaches in otorhinolaryngological practice, especially in the framework of the therapy of vocal fold (VF) scar lesions. The used conservativ...

    Authors: Mikhail Svistushkin, Anastasia Shpichka, Polina Bikmulina, Alexey Fayzullin, Anna Zolotova, Nastasia Kosheleva, Liliya Selezneva, Boris Shavkuta, Viktoria Lobacheva, Anna Nikiforova, Peter Kochetkov, Svetlana Kotova, Svetlana Starostina, Anatoly Shekhter, Andrey Svistunov, Valeriy Svistushkin…
    Citation: Stem Cell Research & Therapy 2023 14:303
  16. Although the efficacy and safety of mesenchymal stem cell therapy for liver cirrhosis have been demonstrated in several studies. Clinical cases of mesenchymal stem cell therapy for patients with liver cirrhosi...

    Authors: Wenming Lu, Jiayang Qu, Longxiang Yan, Xingkun Tang, Xuesong Wang, Anqi Ye, Zhengwei Zou, Lincai Li, Junsong Ye and Lin Zhou
    Citation: Stem Cell Research & Therapy 2023 14:301
  17. Granulocyte colony-stimulating factor (G-CSF)-mediated mobilization of hematopoietic stem cells (HSCs) is a well-established method to prepare HSCs for transplantation nowadays. A sufficient number of HSCs is ...

    Authors: Tso-Fu Wang, Yu-Shan Liou, Shang-Hsien Yang, Guan-Ling Lin, Ya-Wen Chiang, Te-Sheng Lien, Chi-Cheng Li, Jen-Hung Wang, Hsin-Hou Chang and Der-Shan Sun
    Citation: Stem Cell Research & Therapy 2023 14:300
  18. Authors: Yun Xu, Masoud Nasri, Benjamin Dannenmann, Perihan Mir, Azadeh Zahabi, Karl Welte, Tatsuya Morishima and Julia Skokowa
    Citation: Stem Cell Research & Therapy 2023 14:299

    The original article was published in Stem Cell Research & Therapy 2021 12:112

  19. Treatments for skin injuries have recently advanced tremendously. Such treatments include allogeneic and xenogeneic transplants and skin substitutes such as tissue-engineered skin, cultured cells, and stem cel...

    Authors: Wan Tai Seet, Mohd Asyraf Mat Afandi, Mohamad Fikeri Ishak, Muhammad Najib Fathi Hassan, Nazeha Ahmat, Min Hwei Ng and Manira Maarof
    Citation: Stem Cell Research & Therapy 2023 14:298
  20. Menstrual blood-derived cells show regenerative potential as a mesenchymal stem cell and may therefore be a novel stem cell source of treatment for refractory infertility with injured endometrium. However, the...

    Authors: Satoshi Hosoya, Ryo Yokomizo, Harue Kishigami, Yukiko Fujiki, Erika Kaneko, Mitsuyoshi Amita, Takakazu Saito, Hiroshi Kishi, Haruhiko Sago, Aikou Okamoto and Akihiro Umezawa
    Citation: Stem Cell Research & Therapy 2023 14:297
  21. Direct cardiac reprogramming is currently being investigated for the generation of cells with a true cardiomyocyte (CM) phenotype. Based on the original approach of cardiac transcription factor-induced reprogr...

    Authors: Dipthi Bachamanda Somesh, Kristin Klose, Janita A. Maring, Désirée Kunkel, Karsten Jürchott, Stephanie I. Protze, Oliver Klein, Grit Nebrich, Matthias Becker, Ulrike Krüger, Timo Z. Nazari-Shafti, Volkmar Falk, Andreas Kurtz, Manfred Gossen and Christof Stamm
    Citation: Stem Cell Research & Therapy 2023 14:296
  22. Natural killer (NK) cells hold great promise in treating diverse hematopoietic and solid tumors. Despite their availability from peripheral blood and cord blood, stem cell-derived NK cells offer an 'off-the-sh...

    Authors: Wei Wen, Xiang Chen, Xin-Yi Shen, Hua-Yu Li, Feng Zhang, Feng-Qi Fang and Xiao-Bing Zhang
    Citation: Stem Cell Research & Therapy 2023 14:295
  23. Ever since its introduction as a genetic tool, the Cre-lox system has been widely used for molecular genetic studies in vivo in the context of health and disease, as it allows time- and cell-specific gene modi...

    Authors: Despoina Mademtzoglou, Perla Geara, Philippos Mourikis and Frederic Relaix
    Citation: Stem Cell Research & Therapy 2023 14:294
  24. Peritoneal fibrosis (PF) is a pathophysiological condition caused by a variety of pathogenic factors. The most important features of PF are mesothelial–mesenchymal transition and accumulation of activated (myo...

    Authors: Weiyan Huang, Demeng Xia, Wendi Bi, Xueli Lai, Bing Yu and Wei Chen
    Citation: Stem Cell Research & Therapy 2023 14:293
  25. Understanding mechanisms and manifestations of cardiovascular risk factors, including diabetes, on vascular cells such as endothelial cells, pericytes, and vascular smooth muscle cells, remains elusive partly ...

    Authors: Hojjat Naderi-Meshkin, Victoria A. Cornelius, Magdalini Eleftheriadou, Koray Niels Potel, Wiwit Ananda Wahyu Setyaningsih and Andriana Margariti
    Citation: Stem Cell Research & Therapy 2023 14:292
  26. Abdominal obesity is appreciated as a major player in insulin resistance and metabolically dysfunctional adipose tissue. Inappropriate extracellular matrix (ECM) remodelling and functional alterations in human...

    Authors: Xueya Han, Weihong Li, Xu He, Xin Lu, Yu Zhang, Yaqiong Li, Guoyun Bi, Xuqing Ma, Xiaowu Huang, Rixing Bai and Haiyan Zhang
    Citation: Stem Cell Research & Therapy 2023 14:291
  27. Neurosphere medium (NSM) and self-renewal medium (SRM) were widely used to isolate enteric neural stem cells (ENSCs) in the form of neurospheres. ENSCs or their neurosphere forms were neurogenic and gliogenic,...

    Authors: Jeng-Chang Chen, Wendy Yang, Li-Yun Tseng and Hsueh-Ling Chang
    Citation: Stem Cell Research & Therapy 2023 14:290
  28. Mesenchymal stromal cells (MSCs) have a dynamic secretome that plays a critical role in tissue repair and regeneration. However, studying the MSC secretome in mixed-culture disease models remains challenging. ...

    Authors: Jeremy D. Burgess, Danilyn Amerna, Emily S. Norton, Tammee M. Parsons, Ralph B. Perkerson III, Ayman H. Faroqi, Zbigniew K. Wszolek, Hugo Guerrero Cazares, Takahisa Kanekiyo, Marion Delenclos and Pamela J. McLean
    Citation: Stem Cell Research & Therapy 2023 14:289
  29. Liver fibrosis is prevalent among chronic diseases of the liver and represents a major health burden worldwide. Growth differentiation factor 7 (GDF7), a member of the TGFβ protein superfamily, has been recent...

    Authors: Defu Kong, Apostolos Mourtzinos, Janette Heegsma, Hans Blokzijl, Vincent E. de Meijer and Klaas Nico Faber
    Citation: Stem Cell Research & Therapy 2023 14:288
  30. Evolving mutations of the novel coronavirus continue to fuel up the pandemic. The virus affects the human respiratory system along with other body systems, causing several sequelae in the survivors of the dise...

    Authors: Ridhima Vij, Hosu Kim, Hyeonggeun Park, Thanh Cheng, Djamchid Lotfi and Donna Chang
    Citation: Stem Cell Research & Therapy 2023 14:287
  31. Stem cell therapy is a promising therapeutic approach for inherited retinal diseases (IRDs). This study aims to quantitatively examine the effectiveness and safety of stem cell therapy for patients with IRDs, ...

    Authors: Xiaodong Chen, Ningda Xu, Jiarui Li, Mingwei Zhao and Lvzhen Huang
    Citation: Stem Cell Research & Therapy 2023 14:286
  32. Previous studies have verified the dysfunction of mesenchymal stem cells (MSCs) for immunoregulation in acquired aplastic anemia (AA) patients. Exosomes derived from MSCs can partially substitute MSCs acting a...

    Authors: Shichong Wang, Jiali Huo, Yilin Liu, Lingyun Chen, Xiang Ren, Xingxin Li, Min Wang, Peng Jin, Jinbo Huang, Neng Nie, Jing Zhang, Yingqi Shao, Meili Ge and Yizhou Zheng
    Citation: Stem Cell Research & Therapy 2023 14:285
  33. Human umbilical cord mesenchymal stem cells (hUC-MSCs) are widely used in cell therapy due to their robust immunomodulatory and tissue regenerative capabilities. Currently, the predominant method for obtaining...

    Authors: Xia Wang, Liming Ouyang, Wenxia Chen, Yulin Cao and Lixin Zhang
    Citation: Stem Cell Research & Therapy 2023 14:284
  34. Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease characterized by synovial inflammation-mediated progressive destruction of the cartilage and bone, resulting in reduced quality of life. W...

    Authors: Eun Wha Choi, I.-Rang Lim, Ji Hong Park, Jiwoo Song, Bongkum Choi and Sungjoo Kim
    Citation: Stem Cell Research & Therapy 2023 14:283
  35. T helper 2 (Th2) cells are thought to play critical roles in allergic conjunctivitis (AC). They release inflammatory cytokines to promote an allergic response in AC. Due to individual heterogeneity and long-te...

    Authors: Dongli Li, Qingjian Ou, Qi Shen, Michael Mingze Lu, Jing-Ying Xu, Caixia Jin, Furong Gao, Juan Wang, Jingfa Zhang, Jieping Zhang, Jiao Li, Lixia Lu, Guo-Tong Xu and Haibin Tian
    Citation: Stem Cell Research & Therapy 2023 14:281
  36. In vitro production of hematopoietic stem/progenitor cells (HSPCs) from human-induced pluripotent stem cells (hiPSCs) provides opportunities for fundamental research, disease modeling, and large-scale producti...

    Authors: Chuti Laowtammathron, Chanchao Lorthongpanich, Nittaya Jiamvoraphong, Pimonwan Srisook, Phatchanat Klaihmon, Pakpoom Kheolamai, Sudjit Luanpitpong and Surapol Issaragrisil
    Citation: Stem Cell Research & Therapy 2023 14:279
  37. Human induced pluripotent stem cell-derived endothelial cells (hiPSC-ECs) exhibit the potential to repair the injured heart after myocardial infarction (MI) by promoting neovascularization and cardiomyocyte su...

    Authors: Hao Li, Lu Wang, Teng Ma, Zhongmin Liu and Ling Gao
    Citation: Stem Cell Research & Therapy 2023 14:278
  38. As a kind of mesenchymal-like stromal cells, endometrial regenerative cells (ERCs) have been demonstrated effective in the treatment of Concanavalin A (Con A)-induced hepatitis. However, the therapeutic mechan...

    Authors: Hong Qin, Chenglu Sun, Dejun Kong, Yanglin Zhu, Bo Shao, Shaohua Ren, Hongda Wang, Jingyi Zhang, Yini Xu and Hao Wang
    Citation: Stem Cell Research & Therapy 2023 14:277
  39. Identification of promising targeted antigens that exhibited cancer-specific expression is a crucial step in the development of novel antibody-targeted therapies. We here aimed to investigate the anti-tumor ac...

    Authors: Hui-Qi Liu, Li-Xin Sun, Long Yu, Jun Liu, Li-Chao Sun, Zhi-Hua Yang, Xiong Shu and Yu-Liang Ran
    Citation: Stem Cell Research & Therapy 2023 14:273
  40. Though articular cartilage stem cell (ACSC)-based therapies have been demonstrated to be a promising option in the treatment of diseased joints, the wide variety of cell isolation, the unknown therapeutic targ...

    Authors: Zhi-Ling Li, Xiao-Tong Li, Rui-Cong Hao, Fei-Yan Wang, Yu-Xing Wang, Zhi-Dong Zhao, Pei-Lin Li, Bo-Feng Yin, Ning Mao, Li Ding and Heng Zhu
    Citation: Stem Cell Research & Therapy 2023 14:253
  41. Extracellular vesicles (EVs) from human umbilical cord mesenchymal stem cells (hUMSCs) are widely considered to be the best mediators for cell-free therapy. An understanding of their composition, especially RN...

    Authors: Dong Yu, Yue Mei, Ling Wang, Yunpeng Zhao, Xingfei Fan, Dong Liang, Li Li, Jie Zhu, Sisi Bi, Xue Wang, Zhongquan Qi, Lie Zhu and Yue Wang
    Citation: Stem Cell Research & Therapy 2023 14:272
  42. Inflammatory bowel disease (IBD) is a global health problem in which gut microbiota dysbiosis plays a pivotal pathogenic role. Mesenchymal stem cells (MSCs) therapy has emerged as a prospective novel tool for ...

    Authors: Airu Liu, Xiaonan Liang, Wenxin Wang, Chen Wang, Jia Song, Jinbo Guo, Donglei Sun, Dong Wang, Mei Song, Jiaming Qian and Xiaolan Zhang
    Citation: Stem Cell Research & Therapy 2023 14:271
  43. Recent studies have shown that mesenchymal stem cell (MSC) therapy has potential therapeutic effects for patients with end-stage liver diseases. However, a consensus on the efficacy and safety of MSCs has not ...

    Authors: Huimin Wang, Weiqi Yao, Yuyan Wang, Haibo Dong, Tengyun Dong, Wangyi Zhou, Lingling Cui, Lulu Zhao, Yu Zhang, Lei Shi and Yingan Jiang
    Citation: Stem Cell Research & Therapy 2023 14:267
  44. Down syndrome (DS) clinical multisystem condition is generally considered the result of a genetic imbalance generated by the extra copy of chromosome 21. Recent discoveries, however, demonstrate that the molec...

    Authors: Salvatore Vaiasicca, Gianmarco Melone, David W. James, Marcos Quintela, Alessandra Preziuso, Richard H. Finnell, Robert Steven Conlan, Lewis W. Francis and Bruna Corradetti
    Citation: Stem Cell Research & Therapy 2023 14:265

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