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  1. Mesenchymal stem/stromal cells (MSCs) are multipotent cells with strong tissue repair and immunomodulatory properties. Due to their ability to repress pathogenic immune responses, and in particular T cell resp...

    Authors: Waseem Akhter, Jean Nakhle, Loïc Vaillant, Geneviève Garcin, Cécile Le Saout, Matthieu Simon, Carole Crozet, Farida Djouad, Christian Jorgensen, Marie-Luce Vignais and Javier Hernandez
    Citation: Stem Cell Research & Therapy 2023 14:12
  2. Hypoimmunogenic human pluripotent stem cells (hPSCs) are expected to serve as an unlimited cell source for generating universally compatible “off-the-shelf” cell grafts. However, whether the engineered hypoimm...

    Authors: Yifan Chen, Yanjie Zhou, Zhongshu Zhou, Yujiang Fang, Lin Ma, Xiaoqing Zhang, Jie Xiong and Ling Liu
    Citation: Stem Cell Research & Therapy 2023 14:11
  3. Mesenchymal stromal cell (MSC) transplantation therapy is a promising therapy for stroke patients. In parallel, rehabilitation with physical exercise could ameliorate stroke-induced neurological impairment. In...

    Authors: Satoru Yabuno, Takao Yasuhara, Takayuki Nagase, Satoshi Kawauchi, Chiaki Sugahara, Yosuke Okazaki, Kakeru Hosomoto, Susumu Sasada, Tatsuya Sasaki, Naoki Tajiri, Cesar V. Borlongan and Isao Date
    Citation: Stem Cell Research & Therapy 2023 14:10

    The Correction to this article has been published in Stem Cell Research & Therapy 2023 14:123

  4. Bone tissue engineering (BTE) emerged as one of the exceptional means for bone defects owing to it providing mechanical supports to guide bone tissue regeneration. Great advances have been made to facilitate t...

    Authors: Hongqi Zhao, Chaoxu Liu, Yang Liu, Qing Ding, Tianqi Wang, Hao Li, Hua Wu and Tian Ma
    Citation: Stem Cell Research & Therapy 2023 14:7
  5. Multiple sclerosis (MS) is the most frequent non-traumatic neurological debilitating disease among young adults with no cure. Over recent decades, efforts to treat neurodegenerative diseases have shifted to re...

    Authors: Mariam F. Farid, Yara S. Abouelela, Noha A. E. Yasin, Asmaa K. Al-Mokaddem, Abdelbary Prince, Marwa A. Ibrahim and Hamdy Rizk
    Citation: Stem Cell Research & Therapy 2023 14:6
  6. Cellular therapy seems to be an innovative therapeutic alternative for which mesenchymal stem cells (MSCs) have been shown to be effective for interstitial and hemorrhagic cystitis. However, the action of MSCs...

    Authors: Clément Brossard, Anne-Laure Pouliet, Anne‐Charlotte Lefranc, Mohamedamine Benadjaoud, Morgane Dos Santos, Christelle Demarquay, Valerie Buard, Marc Benderitter, Jean-Marc Simon, Fabien Milliat and Alain Chapel
    Citation: Stem Cell Research & Therapy 2023 14:5
  7. Cell therapy is a key technology to prevent sacrificing normal skin. Although some studies have shown the promise of human epidermal stem cells (EpiSCs), the efficacy, biosafety and quality control of EpiSC th...

    Authors: Xiaohong Zhao, Xue Li, Ying Wang, Yicheng Guo, Yong Huang, Dalun Lv, Mingxing Lei, Shicang Yu, Gaoxing Luo and Rixing Zhan
    Citation: Stem Cell Research & Therapy 2023 14:4
  8. Alzheimer’s disease (AD) is a common progressive neurodegenerative disease characterized by memory impairments, and there is no effective therapy. Neural stem/progenitor cell (NSPC) has emerged as potential no...

    Authors: Zijing Zhou, Ben Shi, Yaxing Xu, Jinyu Zhang, Xin liu, Xinghong Zhou, Baofeng Feng, Jun Ma and Huixian Cui
    Citation: Stem Cell Research & Therapy 2023 14:3
  9. Traumatic brain injury (TBI) is a disease with high mortality and morbidity, which leads to severe neurological dysfunction. Neurogenesis has provided therapeutic options for treating TBI. Brain derived neurot...

    Authors: Na Wu, Xiaochuan Sun, Chao Zhou, Jin Yan and Chongjie Cheng
    Citation: Stem Cell Research & Therapy 2023 14:2
  10. Transplantation of differentiated cells from human-induced pluripotent stem cells (hiPSCs) holds great promise for clinical treatments. Eliminating the risk factor of malignant cell transformation is essential...

    Authors: Kensuke Sakuma, Noriko Tsubooka-Yamazoe, Kiyohiro Hashimoto, Nozomu Sakai, Shinya Asano, Saori Watanabe-Matsumoto, Takeshi Watanabe, Bunnai Saito, Hirokazu Matsumoto, Hikaru Ueno, Ryo Ito and Taro Toyoda
    Citation: Stem Cell Research & Therapy 2023 14:1
  11. BMP9-stimulated DPSCs, SCAPs and PDLSCs are effective candidates for repairing maxillofacial bone defects in tissue engineering, while the most suitable seed cell source among these three hDMSCs and the optima...

    Authors: Yuxin Zhang, Wenping Luo, Liwen Zheng, Jing Hu, Li Nie, Huan Zeng, Xi Tan, Yucan Jiang, Yeming Li, Tianyu Zhao, Zhuohui Yang, Tong-Chuan He and Hongmei Zhang
    Citation: Stem Cell Research & Therapy 2022 13:535
  12. Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2 (MECP2), is one of the most prevalent neurodevelopmental disorders in girls. However, the underlying mechanism of MECP2 remains l...

    Authors: Ya-Jie Xu, Pei-Pei Liu, Zhong-Ze Yan, Ting-Wei Mi, Ying-Ying Wang, Qian Li, Zhao-Qian Teng and Chang-Mei Liu
    Citation: Stem Cell Research & Therapy 2022 13:534
  13. Bone marrow mesenchymal stromal cells (BMSCs) are promising for therapeutic use in cartilage repair, because of their capacity to differentiate into chondrocytes. Often, in vitro differentiation protocols empl...

    Authors: Daniele Zuncheddu, Elena Della Bella, Dalila Petta, Cecilia Bärtschi, Sonja Häckel, Moritz C. Deml, Martin J. Stoddart, Sibylle Grad and Valentina Basoli
    Citation: Stem Cell Research & Therapy 2022 13:533
  14. Sprouting angiogenesis is an important mechanism for morphogenetic phenomena, including organ development, wound healing, and tissue regeneration. In regenerative medicine, therapeutic angiogenesis is a clinic...

    Authors: Takanori Sano, Tadaaki Nakajima, Koharu Alicia Senda, Shizuka Nakano, Mizuho Yamato, Yukinori Ikeda, Hedele Zeng, Jun-ichi Kawabe and Yukiko T. Matsunaga
    Citation: Stem Cell Research & Therapy 2022 13:532
  15. Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (iPSC-CMs) do not display all hallmarks of mature primary cardiomyocytes, especially the ability to use fatty acids (FA) as an energy source, c...

    Authors: Nino Chirico, Elise L. Kessler, Renée G. C. Maas, Juntao Fang, Jiabin Qin, Inge Dokter, Mark Daniels, Tomo Šarić, Klaus Neef, Jan-Willem Buikema, Zhiyong Lei, Pieter A. Doevendans, Joost P. G. Sluijter and Alain van Mil
    Citation: Stem Cell Research & Therapy 2022 13:531
  16. Authors: Rongchuan Yue, Wenbin Fu, Xiang Liao, Cong Lan, Qiao Liao, Liangpeng Li, Dezhong Yang, Xuewei Xia, Xiongwen Chen, Chunyu Zeng and Wei Eric Wang
    Citation: Stem Cell Research & Therapy 2022 13:530

    The original article was published in Stem Cell Research & Therapy 2017 8:17

  17. Tissue organoids generated from human pluripotent stem cells are valuable tools for disease modelling and to understand developmental processes. While recent progress in human cardiac organoids revealed the ab...

    Authors: Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin-Han Loh, Omer An, Henry He Yang, Veerabrahma Pratap Seshachalam, Judice L. Y. Koh, Woon-Khiong Chan, Shi Yan Ng and Boon Seng Soh
    Citation: Stem Cell Research & Therapy 2022 13:529
  18. Nowadays, diabetes mellitus is known as a silent killer because individual is not aware that he has the disease till the development of its complications. Many researchers have studied the use of stem cells in...

    Authors: Alyaa Farid, Hebatallah Haridyy, Salma Ashraf, Selim Ahmed and Gehan Safwat
    Citation: Stem Cell Research & Therapy 2022 13:528
  19. Brain tumors are one of the most mortal cancers, leading to many deaths among kids and adults. Surgery, chemotherapy, and radiotherapy are available options for brain tumor treatment. However, these methods ar...

    Authors: Elham Ghasempour, Shilan Hesami, Elaheh Movahed, Saeed Heidari keshel and Mohammad Doroudian
    Citation: Stem Cell Research & Therapy 2022 13:527
  20. The effects of traumatic brain injury (TBI) can include physical disability and even death. The development of effective therapies to promote neurological recovery is still a challenging problem. 3D-printed bi...

    Authors: Xiao-Yin Liu, Zhe-Han Chang, Chong Chen, Jun Liang, Jian-Xin Shi, Xiu Fan, Qi Shao, Wei-Wei Meng, Jing-Jing Wang and Xiao-Hong Li
    Citation: Stem Cell Research & Therapy 2022 13:525
  21. Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by muscu...

    Authors: Łukasz Pulik, Bartosz Mierzejewski, Aleksandra Sibilska, Iwona Grabowska, Maria Anna Ciemerych, Paweł Łęgosz and Edyta Brzóska
    Citation: Stem Cell Research & Therapy 2022 13:523
  22. MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules encoded by endogenous genes, which play a vital role in cell generation, metabolism, apoptosis and stem cell differentiation. C3H10T1/2, a mesenc...

    Authors: Wei Huang, Xiaoyue Wu, Shuaixi Xiang, Mingxin Qiao, Hanfei Li, Yujie Zhu, Zhou Zhu and Zhihe Zhao
    Citation: Stem Cell Research & Therapy 2022 13:521
  23. Mesenchymal stem cells (MSCs) driven gene directed enzyme prodrug therapy is a promising approach to deliver therapeutic agents to target heterogenous solid tumours. To democratize such a therapy, cryopreserva...

    Authors: Yoon Khei Ho, Kin Man Loke, Jun Yung Woo, Yee Lin Lee and Heng-Phon Too
    Citation: Stem Cell Research & Therapy 2022 13:519
  24. Bone-related diseases are major contributors to morbidity and mortality in elderly people and the current treatments result in insufficient healing and several complications. One of the promising areas of rese...

    Authors: Armin Ahmadi, Radman Mazloomnejad, Mohammadreza Kasravi, Babak Gholamine, Soheyl Bahrami, Mohammad Mahdi Sarzaeem and Hassan Niknejad
    Citation: Stem Cell Research & Therapy 2022 13:518
  25. Human umbilical cord mesenchymal stem cells (hUC-MSCs) are increasingly being studied in clinical trials of end-stage liver disease because of their good tissue repair and anti-inflammatory effects. hUC-MSC ex...

    Authors: Ying Shi, Xiaoguang Yang, Shuyue Wang, Yulun Wu, Lihua Zheng, Yufang Tang, Yanhang Gao and Junqi Niu
    Citation: Stem Cell Research & Therapy 2022 13:517
  26. Endothelial progenitor cells (EPCs) contribute to the recovery of neurological function after ischemic stroke. Indirect revascularization has exhibited promising effects in the treatment of cerebral ischemia r...

    Authors: Kuo-Chuan Wang, Ling-Yu Yang, Jing-Er Lee, Vicent Wu, Te-Fu Chen, Sung-Tsang Hsieh and Meng-Fai Kuo
    Citation: Stem Cell Research & Therapy 2022 13:516
  27. Tendon regeneration is difficult because detailed knowledge about tendon progenitor cells (TPCs), which produce tenocytes to repair tendon tissue, has not been revealed. Mohawk homeobox (MKX) is a marker of TP...

    Authors: Yuki Fujisawa, Lu Ming, Daisuke Yamada, Tomoka Takao and Takeshi Takarada
    Citation: Stem Cell Research & Therapy 2022 13:515
  28. The mesenchymal stem cells (MSCs) were used to repair tissue injury. However, the treatment effect was not satisfactory. We investigated whether lncRNA MIR155HG could promote survival and migration of MSCs und...

    Authors: Xiao Bai, Zaiwen Qi, Mingzhen Zhu, Zhuangzhuang Lu, Xin Zhao, Lining Zhang and Guangmin Song
    Citation: Stem Cell Research & Therapy 2022 13:512
  29. Bone injury plagues millions of patients worldwide every year, and it demands a heavy portion of expense from the public medical insurance system. At present, orthopedists think that autologous bone transplant...

    Authors: Yu-Hao Wang, Cheng-Zhi Zhao, Ren-Yi Wang, Qian-Xin Du, Ji-Yuan Liu and Jian Pan
    Citation: Stem Cell Research & Therapy 2022 13:511

    The Correction to this article has been published in Stem Cell Research & Therapy 2022 13:524

  30. Mesenchymal stem cells (MSCs) have shown immense therapeutic potential for various brain diseases. Intrathecal administration of MSCs may enhance their recruitment to lesions in the central nervous system, but...

    Authors: Ye Ran, Yankai Dong, Yuejiao Li, Jundong Xie, Shubin Zeng, Chuanlei Liang, Wei Dai, Wenjing Tang, Yaojiong Wu and Shengyuan Yu
    Citation: Stem Cell Research & Therapy 2022 13:507
  31. Authors: Qin He, Lingshu Wang, Ruxing Zhao, Fei Yan, Sha Sha, Chen Cui, Jia Song, Huiqing Hu, Xinghong Guo, Mengmeng Yang, Yixin Cui, Yujing Sun, Zheng Sun, Fuqiang Liu, Ming Dong, Xinguo Hou…
    Citation: Stem Cell Research & Therapy 2022 13:505
  32. Cell-based therapy using adipose-derived mesenchymal stem cells (ADSCs) is a promising treatment strategy for neurogenic bladder (NB) associated with spinal cord injury (SCI). However, therapeutic efficacy is ...

    Authors: Jiasheng Chen, Lin Wang, Meng Liu, Guo Gao, Weixin Zhao, Qiang Fu and Ying Wang
    Citation: Stem Cell Research & Therapy 2022 13:503
  33. Allogeneic therapeutic cells may be rejected if they express HLA alleles not found in the recipient. As finding cell donors with a full HLA match to a recipient requires vast donor pools, the use of HLA homozy...

    Authors: Jonna Clancy, Kati Hyvärinen, Jarmo Ritari, Tiina Wahlfors, Jukka Partanen and Satu Koskela
    Citation: Stem Cell Research & Therapy 2022 13:502
  34. Human dermal fibroblasts (HDFs) have the potential to differentiate into vascular endothelial cells (VECs), but their differentiation rate is low and the mechanism involved is not clear. The small molecule pat...

    Authors: XiaoLing Cui, XiaoTan Wang, Jie Wen, Xiao Li, Nan Li, XuXiao Hao, BaoXiang Zhao, Xunwei Wu and JunYing Miao
    Citation: Stem Cell Research & Therapy 2022 13:501
  35. Localized scleroderma causes cosmetic disfigurement, joint contractures, and other functional impairment, but no currently available medications can reverse the resulting skin lesions. Fat grafting is benefici...

    Authors: Jing Wang, Junrong Cai, Qian Zhang, Jiaqing Wen, Yunjun Liao and Feng Lu
    Citation: Stem Cell Research & Therapy 2022 13:499
  36. In enteric neural stem cell (ENSC) therapy for enteric neuropathy, the gut is ostensibly accessible via laparotomy, laparoscopy or endoscopy, whereas its elongated configuration and multilayered structures sub...

    Authors: Jeng-Chang Chen
    Citation: Stem Cell Research & Therapy 2022 13:498

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