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  1. A marked egg-induced CD4+ T cell programmed inflammation and subsequent hepatic fibrosis characterize the pathogenesis of schistosomiasis. Mesenchymal stem cell (MSC) has been extensively studied for the treatmen...

    Authors: Chao Liu, Yi-shu Zhang, Fang Chen, Xiao-ying Wu, Bei-bei Zhang, Zhong-dao Wu and Jun-xia Lei

    Citation: Stem Cell Research & Therapy 2020 11:217

    Content type: Research

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  2. In periodontal tissue engineering, periodontal ligament stem cells derived from patients with periodontitis (P-PDLSCs) are among the most promising and accessible stem cells for repairing disrupted alveolar bo...

    Authors: Han Li, Yuejia Deng, Minmin Tan, Ge Feng, Yunchun Kuang, Jie Li and Jinlin Song

    Citation: Stem Cell Research & Therapy 2020 11:215

    Content type: Research

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  3. Multiple studies have reported that mesenchymal stem cell (MSC) therapy has beneficial effects in experimental models of sepsis. However, this finding remains inconclusive. This study was performed to systemat...

    Authors: Xue-Yi Sun, Xian-Fei Ding, Huo-Yan Liang, Xiao-Juan Zhang, Shao-Hua Liu, Bing-Han, Xiao-Guang Duan and Tong-Wen Sun

    Citation: Stem Cell Research & Therapy 2020 11:214

    Content type: Research

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  4. Idiopathic pulmonary fibrosis is a chronic, progressive, and severe disease with a limited response to currently available therapies. Epithelial cell injury and failure of appropriate healing or regeneration a...

    Authors: Belén Alvarez-Palomo, Luis Ignacio Sanchez-Lopez, Yuben Moodley, Michael J. Edel and Anna Serrano-Mollar

    Citation: Stem Cell Research & Therapy 2020 11:213

    Content type: Research

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  5. The therapeutic effects of adipose-derived mesenchymal stem cell (ADSC) transplantation have been demonstrated in several models of central nervous system (CNS) injury and are thought to involve the modulation...

    Authors: Zhilai Zhou, Xiaobo Tian, Biling Mo, Huali Xu, Li Zhang, Lishan Huang, Shun Yao, Zixiang Huang, Yeyang Wang, Huan Xie, Liwei Xu and Hui Zhang

    Citation: Stem Cell Research & Therapy 2020 11:212

    Content type: Research

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  6. The differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts (OBs) is a prerequisite for bone formation. However, little is known about the definitive surface markers for OBs during osteogenesis.

    Authors: Hyun Min Lee, Se-Ri Seo, Jeeseung Kim, Min Kyu Kim, Hyosun Seo, Kyoung Soo Kim, Young-Joo Jang and Chun Jeih Ryu

    Citation: Stem Cell Research & Therapy 2020 11:210

    Content type: Research

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  7. Noonan syndrome (NS) is a developmental disorder caused by mutations of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2). Although NS patients have diverse neurological manifestations, th...

    Authors: Younghee Ju, Jun Sung Park, Daejeong Kim, Bumsoo Kim, Jeong Ho Lee, Yoonkey Nam, Han-Wook Yoo, Beom Hee Lee and Yong-Mahn Han

    Citation: Stem Cell Research & Therapy 2020 11:209

    Content type: Research

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    The Correction to this article has been published in Stem Cell Research & Therapy 2020 11:282

  8. The novel coronavirus disease 2019 (COVID-19) has grown to be a global public health emergency since patients were first detected in Wuhan, China. Thus far, no specific drugs or vaccines are available to cure ...

    Authors: Yingxin Zhang, Jie Ding, Shaoda Ren, Weihua Wang, Yapei Yang, Shuangjing Li, Min Meng, Tiejun Wu, Daliang Liu, Suochen Tian, Hui Tian, Shuangfeng Chen and Changhui Zhou

    Citation: Stem Cell Research & Therapy 2020 11:207

    Content type: Short report

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  9. Exosomes derived from mesenchymal stem cells (MSC-exos) have been demonstrated with great potential in the treatment of multiple human diseases including acute kidney injury (AKI) by virtue of their intrinsic ...

    Authors: Jingyuan Cao, Bin Wang, Taotao Tang, Linli Lv, Zhaoying Ding, Zuolin Li, Ruoyu Hu, Qing Wei, Anran Shen, Yuqi Fu and Bicheng Liu

    Citation: Stem Cell Research & Therapy 2020 11:206

    Content type: Research

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  10. Mesenchymal stromal cell conditioned medium (MSC-CM) contains a cocktail of bioactive factors that act synergistically to induce therapeutic effects. This has been clearly demonstrated by in vivo applications ...

    Authors: K. Shoma Suresh, Samatha Bhat, Bharath Raja Guru, Manjunatha S. Muttigi and Raviraja N. Seetharam

    Citation: Stem Cell Research & Therapy 2020 11:205

    Content type: Research

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  11. Polydatin (PD), extracted from Polygonum cuspidatum, has shown potential therapeutic applications due to its antiosteoporotic and anti-inflammatory activities. Our previous study suggested that PD promotes the os...

    Authors: Ying-Shan Shen, Xiao-Jun Chen, Sha-Na Wuri, Fan Yang, Feng-Xiang Pang, Liang-Liang Xu, Wei He and Qiu-Shi Wei

    Citation: Stem Cell Research & Therapy 2020 11:204

    Content type: Research

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  12. Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration. Various somati...

    Authors: Seyedeh-Zahra Seyedrazizadeh, Sara Poosti, Abdoreza Nazari, Mehdi Alikhani, Faezeh Shekari, Farzad Pakdel, Koorosh Shahpasand, Leila Satarian and Hossein Baharvand

    Citation: Stem Cell Research & Therapy 2020 11:203

    Content type: Research

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  13. Increasing evidence has revealed that long non-coding RNAs (lncRNAs) exert critical roles in biological mineralization. As a critical process for dentin formation, odontoblastic differentiation is regulated by...

    Authors: Jialin Zhong, Xinran Tu, Yuanyuan Kong, Liyang Guo, Baishun Li, Wenchao Zhong, Ying Cheng, Yiguo Jiang and Qianzhou Jiang

    Citation: Stem Cell Research & Therapy 2020 11:202

    Content type: Research

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  14. The original article omits an affiliation for authors, He Zhang and Dongjin Wang. The omitted affiliation can be viewed in this Correction article.

    Authors: Xumin Guan, Wanzi Xu, He Zhang, Qian Wang, Jiuyang Yu, Ruyi Zhang, Yamin Chen, Yunlong Xia, Jiaxian Wang and Dongjin Wang

    Citation: Stem Cell Research & Therapy 2020 11:201

    Content type: Correction

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    The original article was published in Stem Cell Research & Therapy 2020 11:73

  15. Accidentally removed parathyroid glands are still challenging in neck surgery, leading to hypoparathyroidism characterized with abnormally low levels of parathyroid hormone. Parathyroid auto-transplantation is...

    Authors: Qiuxia Cui, Dan Zhang, Deguang Kong, Jianing Tang, Xing Liao, Qian Yang, Jiangbo Ren, Yan Gong and Gaosong Wu

    Citation: Stem Cell Research & Therapy 2020 11:200

    Content type: Research

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  16. Osteoarthritis (OA) is a major cause of limb dysfunction, and distraction arthroplasty which generates intermittent hydrostatic pressure (IHP) is an effective approach for OA treatment. However, the result was...

    Authors: Hanhao Dai, Ran Chen, Chang Gui, Tianqi Tao, Yingbin Ge, Xilian Zhao, Ran Qin, Wangxiang Yao, Song Gu, Yiqiu Jiang and Jianchao Gui

    Citation: Stem Cell Research & Therapy 2020 11:199

    Content type: Research

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  17. Cutaneous wound healing represents a morphogenetic response to injury and is designed to restore anatomic and physiological function. Human bone marrow mesenchymal stem cell-derived exosomes (hBM-MSC-Ex) are a...

    Authors: Tiechao Jiang, Zhongyu Wang and Ji Sun

    Citation: Stem Cell Research & Therapy 2020 11:198

    Content type: Research

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  18. The inevitable side effects caused by lifelong immunosuppressive agents in kidney transplantation patients spurred the exploration of novel immunosuppressive strategies with definite curative effects and minim...

    Authors: Lingfei Zhao, Chenxia Hu, Fei Han, Fanghao Cai, Junni Wang and Jianghua Chen

    Citation: Stem Cell Research & Therapy 2020 11:197

    Content type: Review

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  19. Mesendodermal formation during early gastrulation requires the expression of lineage-specific genes, while the regulatory mechanisms during this process have not yet been fully illustrated. TATA box-binding pr...

    Authors: He Liang, Peng Zhang, Hua-Jun Bai, Jijun Huang and Huang-Tian Yang

    Citation: Stem Cell Research & Therapy 2020 11:196

    Content type: Research

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  20. Temperature is an important microenvironmental factor that functions epigenetically in normal embryonic development. However, the effect of hyperthermia in the stem cells is not fully understood. Oct4 is a tig...

    Authors: Mo-bin Cheng, Xue Wang, Yue Huang and Ye Zhang

    Citation: Stem Cell Research & Therapy 2020 11:195

    Content type: Letter

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  21. Recent studies suggest that circulating endothelial progenitor cells (EPCs) may influence the response to cardiac resynchronization therapy (CRT). The aim of this study was to evaluate the effect of CRT on EPC...

    Authors: Gonçalo Cristóvão, James Milner, Pedro Sousa, Miguel Ventura, João Cristóvão, Luís Elvas, Artur Paiva, Lino Gonçalves, Carlos Fontes Ribeiro and Natália António

    Citation: Stem Cell Research & Therapy 2020 11:194

    Content type: Research

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  22. RNA-binding protein, musashi1 (MSI1), is a main protein in asymmetric cell division of the sensory organ precursor cells, whereas its expression is reported to be upregulated in cancers. This protein is a crit...

    Authors: Mahboobeh Forouzanfar, Liana Lachinani, Kianoush Dormiani, Mohammad Hossein Nasr-Esfahani, Ali Osmay Gure and Kamran Ghaedi

    Citation: Stem Cell Research & Therapy 2020 11:193

    Content type: Review

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  23. Acute lung injury (ALI), an increasingly devastating human disorder, is characterized by a multitude of lung changes arising from a wide variety of lung injuries. Viral infection is the main cause of morbidity...

    Authors: Jiang Du, Han Li, Jie Lian, Xinxing Zhu, Liang Qiao and Juntang Lin

    Citation: Stem Cell Research & Therapy 2020 11:192

    Content type: Review

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  24. Some children who have survived cancer will be azoospermic in the future. Performing isolation and purification procedures for spermatogonial stem cells (SSC) is very critical. In this regard, performing the p...

    Authors: Behnaz Ashtari, Azar Shams, Narges Esmaeilzadeh, Sara Tanbakooei, Morteza Koruji, Mojtaba Johari Moghadam, Javad Mohajer Ansari, Adel Johari Moghadam and Ronak Shabani

    Citation: Stem Cell Research & Therapy 2020 11:191

    Content type: Research

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  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Orianne Villard, Mathieu Armanet, Guilhem Couderc, Claire Bony, Jerome Moreaux, Daniele Noël, John De Vos, Bernard Klein, Jean-Luc Veyrune and Anne Wojtusciszyn

    Citation: Stem Cell Research & Therapy 2020 11:190

    Content type: Correction

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    The original article was published in Stem Cell Research & Therapy 2020 11:158

  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yong Yao, Liang Yang, Li-feng Feng, Zhi-wei Yue, Nian-huan Zhao, Zongjin Li and Zuo-xiang He

    Citation: Stem Cell Research & Therapy 2020 11:189

    Content type: Correction

    Published on:

    The original article was published in Stem Cell Research & Therapy 2020 11:136

  27. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Chen-Fei Zhou, Min-Juan Liu, Wei Wang, Sha Wu, Yu-Xin Huang, Guo-Bin Chen, Li-Min Liu, Dong-Xian Peng, Xue-Feng Wang, Xu-Zi Cai, Xiao-Xuan Li, Wan-Qin Feng and Ying Ma

    Citation: Stem Cell Research & Therapy 2020 11:188

    Content type: Correction

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    The original article was published in Stem Cell Research & Therapy 2019 10:287

  28. Similar to humans, the horse is a long-lived, athletic species. The use of mesenchymal stromal cells (MSCs) is a relatively new frontier, but has been used with promising results in treating joint diseases, e....

    Authors: Louise Bundgaard, Allan Stensballe, Kirstine Juul Elbæk and Lise Charlotte Berg

    Citation: Stem Cell Research & Therapy 2020 11:187

    Content type: Research

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  29. The therapeutic effects of mesenchymal stem cells (MSCs) have been limited by their apoptosis induced by oxidative stress after delivery into the injured sites. Therefore, strategies designed to improve the MS...

    Authors: Lianshuang Zhang, Xifeng Wang, Xueyan Lu, Yanchao Ma, Xin Xin, Xiaomin Xu, Siyuan Wang and Yun Hou

    Citation: Stem Cell Research & Therapy 2020 11:186

    Content type: Research

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  30. Human induced pluripotent stem cells (hiPSCs) represent a potentially unlimited source of pancreatic endocrine lineage cells. Although insulin-producing β cells derived from hiPSCs have been successfully induc...

    Authors: Xiao-Fei Yang, Shu-Yan Zhou, Ce Wang, Wei Huang, Ning Li, Fei He and Fu-Rong Li

    Citation: Stem Cell Research & Therapy 2020 11:185

    Content type: Research

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  31. Tendon injuries occur frequently in human and equine athletes. Treatment options are limited, and the prognosis is often poor with functionally deficient scar tissue resulting. Fetal tendon injuries in contras...

    Authors: Y. Z. Paterson, A. Cribbs, M. Espenel, E. J. Smith, F. M. D. Henson and D. J. Guest

    Citation: Stem Cell Research & Therapy 2020 11:184

    Content type: Research

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  32. Mesenchymal stem cells (MSCs) are considered to be an effective tool for regenerative medicine with promising applications for clinical therapy. However, incongruent data has been reported partially owing to t...

    Authors: Xiao Yi, Feng Chen, Fenghua Liu, Qing Peng, Yang Li, Shao Li, Jiang Du, Yi Gao and Yifeng Wang

    Citation: Stem Cell Research & Therapy 2020 11:183

    Content type: Research

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  33. ARDS and ALI are life-threatening diseases with extremely high mortality in patients. Different sources of MSCs could mitigate the symptoms of ALI from diverse mechanisms. Liraglutide is an activator of glucag...

    Authors: Xiaotong Yang, Xiaoying Ma, Ocholi Don, Yuanlin Song, Xiaoyan Chen, Jianwen Liu, Jieming Qu and Yun Feng

    Citation: Stem Cell Research & Therapy 2020 11:182

    Content type: Research

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  34. The dedifferentiation of chondrocytes and the unstable chondrogenic differentiation status of pluripotent mesenchymal stem cells (MSCs) are immense issues in cell-based articular cartilage repair and regenerat...

    Authors: Yu Zhang, Chunxiang Hao, Weimin Guo, Xiaoyu Peng, Mingjie Wang, Zhen Yang, Xu Li, Xueliang Zhang, Mingxue Chen, Xiang Sui, Jiang Peng, Shibi Lu, Shuyun Liu, Quanyi Guo and Qing Jiang

    Citation: Stem Cell Research & Therapy 2020 11:180

    Content type: Research

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  35. Infantile malignant osteopetrosis (IMO) is an autosomal recessive disorder characterized by non-functional osteoclasts and a fatal outcome early in childhood. About 50% of patients have mutations in the TCIRG1 ge...

    Authors: Xiaojie Xian, Roksana Moraghebi, Henrik Löfvall, Anders Fasth, Kim Henriksen, Johan Richter, Niels-Bjarne Woods and Ilana Moscatelli

    Citation: Stem Cell Research & Therapy 2020 11:179

    Content type: Research

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  36. Mesenchymal stem cells (MSCs) have become a promising treatment for spinal cord injury (SCI) due to the fact that they provide a favorable environment. Treatment using MSCs results in a better neurological fun...

    Authors: Peiwen Song, Tianyu Han, Xia Xiang, Ying Wang, Huang Fang, Yang Niu and Cailiang Shen

    Citation: Stem Cell Research & Therapy 2020 11:178

    Content type: Research

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  37. Since cartilage-derived stem/progenitor cells (CSPCs) were first identified in articular cartilage using differential adhesion to fibronectin, their self-renewal capacity and niche-specific lineage preference ...

    Authors: Zita M. Jessop, Ayesha Al-Sabah, Irina N. Simoes, Stephanie E. A. Burnell, Ina Laura Pieper, Catherine A. Thornton and Iain S. Whitaker

    Citation: Stem Cell Research & Therapy 2020 11:177

    Content type: Research

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  38. Cell-based therapy products are supposed to be the most complex medicine products in the history of human medical care. In this study, we established a safety evaluation system for therapeutic stromal cells ba...

    Authors: Yuanyuan Xie, Wei Liu, Shuo Liu, Liudi Wang, Dan Mu, Yi Cui, Yanyan Cui and Bin Wang

    Citation: Stem Cell Research & Therapy 2020 11:176

    Content type: Research

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  39. Advances in regenerative medicine with stem cells have led to clinical trials. Dental/oral tissues are emerging as promising cellular sources of human mesenchymal stem cells. Recently, dental tissue-derived ce...

    Authors: Yoichi Yamada, Sayaka Nakamura-Yamada, Ryutaro Konoki and Shunsuke Baba

    Citation: Stem Cell Research & Therapy 2020 11:175

    Content type: Review

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  40. Skin wounding is very common and may be slow to heal. Increasing evidence shows that exosomes derived from mesenchymal stem cells (MSCs) dramatically enhance skin wound healing in a paracrine manner. However, ...

    Authors: Guifang Zhao, Feilin Liu, Zinan Liu, Kuiyang Zuo, Bo Wang, Yuying Zhang, Xing Han, Aobo Lian, Yuan Wang, Mingsheng Liu, Fei Zou, Pengdong Li, Xiaomei Liu, Minghua Jin and Jin Yu Liu

    Citation: Stem Cell Research & Therapy 2020 11:174

    Content type: Research

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  41. A commentary to “Hertegård, S., Nagubothu, S.R., Malmström, E. et al. Treatment of vocal fold scarring with autologous bone marrow-derived human mesenchymal stromal cells - first phase I/II human clinical stud...

    Authors: Alexia Mattei, Jérémy Magalon, Mélanie Velier, Françoise Dignat-George, Antoine Giovanni and Florence Sabatier

    Citation: Stem Cell Research & Therapy 2020 11:173

    Content type: Commentary

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    The original article was published in Stem Cell Research & Therapy 2020 11:128

    The Commentary to this article has been published in Stem Cell Research & Therapy 2020 11:235

  42. Cardiovascular diseases are the main cause of morbidity and mortality worldwide. Restoring blood supply to ischemic tissues is an essential goal for the successful treatment of these diseases. Growth factor or...

    Authors: Richard Proust, Anne-Charlotte Ponsen, Valérie Rouffiac, Chantal Schenowitz, Florent Montespan, Karine Ser-Le Roux, Frédéric De Leeuw, Corinne Laplace-Builhé, Philippe Mauduit, Edgardo D. Carosella, Sébastien Banzet, Jean-Jacques Lataillade, Nathalie Rouas-Freiss, Georges Uzan and Juliette Peltzer

    Citation: Stem Cell Research & Therapy 2020 11:172

    Content type: Research

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  43. Rheumatoid arthritis (RA) is characterized by joint inflammation and damage to the cartilage and bone in collagen-induced arthritis (CIA). Mesenchymal stem cells (MSCs) can improve articular symptoms and reduc...

    Authors: Jinfang Gao, Gailian Zhang, Ke Xu, Dan Ma, Limin Ren, Jingjing Fan, Jianwen Hou, Jian Han and Liyun Zhang

    Citation: Stem Cell Research & Therapy 2020 11:171

    Content type: Research

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  44. Cancer stem cells (CSCs) have been proposed to be responsible for tumor recurrence and chemo-resistance. Previous studies suggested that miR-153 played essential roles in lung cancer. However, the molecular me...

    Authors: Guoli Zhao, Yueying Zhang, Zhonghua Zhao, Haibo Cai, Xiaogang Zhao, Tong Yang, Weijun Chen, Chengfang Yao, Zhaopeng Wang, Zhaoxia Wang, Chen Han and Hengxiao Wang

    Citation: Stem Cell Research & Therapy 2020 11:170

    Content type: Research

    Published on:

  45. The outbreak of 2019 novel coronavirus disease (COVID-19) worldwide is becoming rapidly a major concern. The number of severe cases has increased dramatically worldwide, while specific treatment options are sc...

    Authors: Shan Liu, Danyi Peng, Huijun Qiu, Ke Yang, Zhou Fu and Lin Zou

    Citation: Stem Cell Research & Therapy 2020 11:169

    Content type: Commentary

    Published on:

  46. Despite recent advances in understanding its pathophysiology and development of novel therapies, asthma remains a serious public health issue worldwide. Combination therapy with inhaled corticosteroids and lon...

    Authors: Fabio S. Aguiar, André S. Melo, Ana Maria S. Araújo, Alexandre P. Cardoso, Sergio Augusto L. de Souza, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Debora G. Xisto, Karina D. Asensi, Lanuza Faccioli, Anna Beatriz S. Salgado, Maria Carolina P. P. Landesmann, Regina C. S. Goldenberg, Bianca Gutfilen, Marcelo M. Morales, Patricia R. M. Rocco…

    Citation: Stem Cell Research & Therapy 2020 11:167

    Content type: Research

    Published on:

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