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  1. The original article [1] contained a minor error regarding the mean diameter of the alginate microcapsules described in relation to Fig. 4 in the Results section. The microcapsules had an actual mean diameter ...

    Authors: Vitor Hugo Santos, João Pedro Hübbe Pfeifer, Jaqueline Brandão de Souza, Betsabéia Heloisa Gentilha Milani, Rogério Antonio de Oliveira, Marjorie Golim Assis, Elenice Deffune, Andrei Moroz and Ana Liz Garcia Alves
    Citation: Stem Cell Research & Therapy 2018 9:259
    Content type: Correction Published on:

    The original article was published in BMC Veterinary Research 2018 14:114

  2. Normal human breast epithelial cells are maintained by the proliferation and differentiation of different human breast epithelial progenitors (HBEPs). However, these progenitor subsets can only be obtained at ...

    Authors: Sumanta Chatterjee, Pratima Basak, Edward Buchel, Leigh C. Murphy and Afshin Raouf
    Citation: Stem Cell Research & Therapy 2018 9:264
    Content type: Short report Published on:

  3. With the development of regenerative medicine, a variety of mesenchymal stem cells (MSCs) are increasingly considered for the treatment of premature ovarian failure (POF). Reportedly, bone marrow-derived MSCs ...

    Authors: Yantao He, Dongmei Chen, Lingling Yang, Qiaoni Hou, Huiming Ma and Xian Xu
    Citation: Stem Cell Research & Therapy 2018 9:263
    Content type: Review Published on:

  4. Skeletal muscle regeneration is possible thanks to unipotent stem cells, which are satellite cells connected to the myofibers. Populations of stem cells other than muscle-specific satellite cells are considere...

    Authors: Kamil Kowalski, Matthieu Dos Santos, Pascal Maire, Maria A. Ciemerych and Edyta Brzoska
    Citation: Stem Cell Research & Therapy 2018 9:258
    Content type: Research Published on:

  5. Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease for which age is the most important risk factor. Different mechanisms associated with aging, including stem cell dysfunction, have been described t...

    Authors: Nayra Cárdenes, Diana Álvarez, Jacobo Sellarés, Yating Peng, Catherine Corey, Sophie Wecht, Seyed Mehdi Nouraie, Swaroop Shanker, John Sembrat, Marta Bueno, Sruti Shiva, Ana L. Mora and Mauricio Rojas
    Citation: Stem Cell Research & Therapy 2018 9:257
    Content type: Research Published on:

  6. Cultivated oral mucosal epithelial cells (OMECs) are widely used in the treatment of limbal stem cell deficiency (LSCD) for their ocular reconstruction capability. As the most important component of the limbal...

    Authors: Xin-Yue Zhao, Hua-Tao Xie, Chao-Ye Duan, Jing Li and Ming-Chang Zhang
    Citation: Stem Cell Research & Therapy 2018 9:256
    Content type: Research Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2018 9:270

  7. Through recent studies, the onset of acute pancreatitis in pancreatic acinar cells (PACs) and the regulatory role of PACs in severe acute pancreatitis (SAP) have been revealed. During the early stages of pancr...

    Authors: Qiang Li, Woo-Jin Song, Min-Ok Ryu, Aryung Nam, Ju-Hyun An, Jin-Ok Ahn, Dong Ha Bhang, Yun Chan Jung and Hwa-Young Youn
    Citation: Stem Cell Research & Therapy 2018 9:255
    Content type: Research Published on:

  8. Inducing donor-specific immunological tolerance, which avoids the complications of long-term immunosuppression, is an important goal in organ transplantation. Interleukin-35 (IL-35), a cytokine identified in 2...

    Authors: Hao Guo, Baozhu Li, Wei Wang, Na Zhao and Haopeng Gao
    Citation: Stem Cell Research & Therapy 2018 9:254
    Content type: Review Published on:

  9. Bone marrow mesenchymal stem cells (BMSC) transfer has been attempted as a therapeutic strategy in experimental lung injury and fibrosis. Reduction of neutrophilic infiltration is one of the mechanisms involve...

    Authors: XiaoSan Su, Liu Yang, YanFeng Yin, Jie Huang, Fei Qiao, Yu Fang, Lu Yu, YinYin Wang, KaiHua Zhou and Jun Wang
    Citation: Stem Cell Research & Therapy 2018 9:253
    Content type: Research Published on:

  10. The increasing number of patients with ovarian insufficiency due to autoimmune disorders, genetic predisposition, or iatrogenic effects of treatment such as cancer therapies necessitates an urgent measure to f...

    Authors: Ashraf Hassanpour, Tahereh Talaei-Khozani, Elias Kargar-Abarghouei, Vahid Razban and Zahra Vojdani
    Citation: Stem Cell Research & Therapy 2018 9:252
    Content type: Research Published on:

  11. It is known that, following a physiological insult, bone marrow-derived mesenchymal stem cells (MSCs) mobilize and home to the site of injury. However, the effect of injury on the function of endogenous MSCs i...

    Authors: Ben Antebi, Kerfoot P. Walker III, Arezoo Mohammadipoor, Luis A. Rodriguez, Robbie K. Montgomery, Andriy I. Batchinsky and Leopoldo C. Cancio
    Citation: Stem Cell Research & Therapy 2018 9:251
    Content type: Research Published on:

  12. Cell therapy for degenerative diseases aims at rescuing tissue damage by delivery of precursor cells. Thus far, this strategy has been mostly unsuccessful due to massive loss of donor cells shortly after trans...

    Authors: Giuliana Di Rocco, Silvia Baldari, Antonietta Gentile, Maurizio Capogrossi and Gabriele Toietta
    Citation: Stem Cell Research & Therapy 2018 9:250
    Content type: Research Published on:

  13. In-vitro spermatogenesis in mammalian species is considered an important topic in reproductive biology. New strategies for achieving a complete version of spermatogenesis ex vivo have been conducted using an o...

    Authors: Keykavos Gholami, Gholamreza Pourmand, Morteza Koruji, Sepideh Ashouri and Mehdi Abbasi
    Citation: Stem Cell Research & Therapy 2018 9:249
    Content type: Research Published on:

  14. Stem cells are increasingly seen as a solution for many health challenges for an ageing population. However, their potential benefits in the clinic are currently curtailed by technical challenges such as high ...

    Authors: Richard Harrison, Hilda Anaid Lugo Leija, Stephanie Strohbuecker, James Crutchley, Sarah Marsh, Chris Denning, Alicia El Haj and Virginie Sottile
    Citation: Stem Cell Research & Therapy 2018 9:248
    Content type: Research Published on:

  15. WNT5A is known to be involved in the pathogenesis of osteoarthritis. This study investigated the molecular mechanism of exosomal miR-92a-3p and WNT5A in chondrogenesis and cartilage degeneration.

    Authors: Guping Mao, Ziji Zhang, Shu Hu, Zhiqi Zhang, Zongkun Chang, Zhiyu Huang, Weiming Liao and Yan Kang
    Citation: Stem Cell Research & Therapy 2018 9:247
    Content type: Research Published on:

  16. This study investigated the therapeutic effects of MSC-derived exosomes (MSC-Exos) on erectile function in a rat model of cavernous nerve injury (CNI).

    Authors: Xi Ouyang, Xiaoyan Han, Zehong Chen, Jiafeng Fang, Xuna Huang and Hongbo Wei
    Citation: Stem Cell Research & Therapy 2018 9:246
    Content type: Research Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2022 13:508

  17. Neurodegenerative disorders have a complex pathology and are characterized by a progressive loss of neuronal architecture in the brain or spinal cord. Neuroprotective agents have demonstrated promising results...

    Authors: Syed Shadab Raza, Aurel Popa Wagner, Yawer S. Hussain and Mohsin Ali Khan
    Citation: Stem Cell Research & Therapy 2018 9:245
    Content type: Review Published on:

  18. Aging is a high risk factor for the development of osteoporosis, a multifactorial age-related progressive disease characterized by reduced bone mass and increased risk of fractures. At the cellular level, the ...

    Authors: Arantza Infante and Clara I. Rodríguez
    Citation: Stem Cell Research & Therapy 2018 9:244
    Content type: Review Published on:

  19. Non-adherent or ultra-low attachment three-dimensional (3D) culture, also called sphere formation assay, has been widely used to assess the malignant phenotype and stemness potential of transformed or cancer c...

    Authors: Weijie Gao, Dinglan Wu, Yuliang Wang, Zhu Wang, Chang Zou, Yong Dai, Chi-Fai Ng, Jeremy Yuen-Chun Teoh and Franky Leung Chan
    Citation: Stem Cell Research & Therapy 2018 9:243
    Content type: Method Published on:

  20. Androgen deprivation (AD) as the first-line treatment for advanced prostate cancer (PCa) is insufficient for a long-term effect. Castration resistance remains the greatest obstacle in PCa clinical therapy. Mes...

    Authors: Yang Yu, Qingyun Zhang, Chengzhong Ma, Xue Yang, Rui Lin, Hongxiang Zhang, Yan Liu, Zhipeng Han and Jiwen Cheng
    Citation: Stem Cell Research & Therapy 2018 9:242
    Content type: Research Published on:

  21. Amyotrophic lateral sclerosis (ALS) is a fatal paralytic disease with no cure or treatment to stop disease progression. Because ALS represents an urgent unmet medical need, a significant number of therapeutics...

    Authors: Luis Barbeito
    Citation: Stem Cell Research & Therapy 2018 9:241
    Content type: Commentary Published on:

    The original article was published in Stem Cell Research & Therapy 2018 9:152

  22. Premature ovarian failure (POF) is a severe complication associated with chemotherapy for female patients of childbearing age. A previous study has shown that bone marrow-derived mesenchymal stem cells (MSCs) ...

    Authors: Xiaoying Chen, Qing Wang, Xinran Li, Qingru Wang, Jiaxin Xie and Xiafei Fu
    Citation: Stem Cell Research & Therapy 2018 9:240
    Content type: Research Published on:

  23. Cell therapy constitutes an attractive alternative to treat stress urinary incontinence. Although promising results have been demonstrated in this field, the procedure requires further optimization. The most c...

    Authors: Anna Burdzinska, Bartosz Dybowski, Weronika Zarychta-Wiśniewska, Agnieszka Kulesza, Marta Butrym, Radoslaw Zagozdzon, Agnieszka Graczyk-Jarzynka, Piotr Radziszewski, Zdzislaw Gajewski and Leszek Paczek
    Citation: Stem Cell Research & Therapy 2018 9:239
    Content type: Research Published on:

  24. Mesenchymal stem/stromal cells derived from chorionic villi of human term placentae (pMSCs) protect human endothelial cells from injury induced by hydrogen peroxide (H2O2). In diabetes, elevated levels of glucose...

    Authors: Y. S. Basmaeil, A. M. Al Subayyil, T. Khatlani, E. Bahattab, M. Al-Alwan, F. M. Abomaray, B. Kalionis, M. A. Alshabibi, A. S. AlAskar and M. H. Abumaree
    Citation: Stem Cell Research & Therapy 2018 9:238
    Content type: Research Published on:

  25. Mesenchymal stem cells (MSCs) play an anti-inflammatory role by secreting certain bioactive molecules to exert their therapeutic effects for disease treatment. However, the underlying mechanism of MSCs in chro...

    Authors: Junyu Fan, Xiaojun Tang, Qian Wang, Zhuoya Zhang, Shufang Wu, Wenchao Li, Shanshan Liu, Genhong Yao, Hongwei Chen and Lingyun Sun
    Citation: Stem Cell Research & Therapy 2018 9:237
    Content type: Research Published on:

  26. In this review we present current evidence on the possibility of umbilical cord tissue cryopreservation for subsequent clinical use. Protocols for obtaining umbilical cord-derived vessels, Wharton’s jelly-base...

    Authors: Irina Arutyunyan, Timur Fatkhudinov and Gennady Sukhikh
    Citation: Stem Cell Research & Therapy 2018 9:236
    Content type: Review Published on:

  27. Cell therapy with bone marrow (BM)-derived progenitors has emerged as a promising therapeutic for refractory angina (RA) patients. In the present study, we evaluated the safety and preliminary efficacy of tran...

    Authors: Beatrice Bassetti, Corrado Carbucicchio, Valentina Catto, Elisa Gambini, Erica Rurali, Alberto Bestetti, Giuseppe Gaipa, Daniela Belotti, Fabrizio Celeste, Matteo Parma, Stefano Righetti, Lorenza Biava, Maurizio Arosio, Alice Bonomi, Piergiuseppe Agostoni, Paolo Scacciatella…
    Citation: Stem Cell Research & Therapy 2018 9:235
    Content type: Research Published on:

  29. In an earlier pilot study with 10 women, we investigated a new approach for therapy of faecal incontinence (FI) due to obstetric trauma, involving ultrasound-guided injection of autologous skeletal muscle-deri...

    Authors: Andrea Frudinger, Rainer Marksteiner, Johann Pfeifer, Eva Margreiter, Johannes Paede and Marco Thurner
    Citation: Stem Cell Research & Therapy 2018 9:233
    Content type: Research Published on:

  30. Periodontal ligament stem cells (PDLSCs) are considered as candidate cells for the regeneration of periodontal and alveolar bone tissues. Antisense to the cerebellar degeneration-related protein 1 transcript (...

    Authors: Xiaobei Li, Yunfei Zheng, Yan Zheng, Yiping Huang, Yixin Zhang, Lingfei Jia and Weiran Li
    Citation: Stem Cell Research & Therapy 2018 9:232
    Content type: Research Published on:

  31. An understanding of the mechanism underlying adipogenic differentiation of human bone marrow-derived mesenchymal stem cells (hMSCs) will provide new therapeutic approaches for many diseases, including osteopor...

    Authors: Yangling Wang, Lei Yang, Xiaofeng Liu, Tao Hong, Tao Wang, Aiwu Dong, Jiangxiong Li, Xiaoyuan Xu and Lingling Cao
    Citation: Stem Cell Research & Therapy 2018 9:231
    Content type: Research Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2019 10:62

  32. Inner ear hair cells as mechanoreceptors are extremely important for hearing. Defects in hair cells are a major cause of deafness. Induced pluripotent stem cells (iPSCs) are promising for regenerating inner ea...

    Authors: Jianling Chen, Fanfan Hong, Cui Zhang, Liang Li, Cuicui Wang, Haosong Shi, Yong Fu and Jinfu Wang
    Citation: Stem Cell Research & Therapy 2018 9:230
    Content type: Research Published on:

  33. The original article [1] contained two minor errors affecting the labelling of Fig. 3d and Figs. 6b & 6c; these errors have now been corrected in the respective figures in the original article.

    Authors: Emily R. Moore, Ya Xing Zhu, Han Seul Ryu and Christopher R. Jacobs
    Citation: Stem Cell Research & Therapy 2018 9:229
    Content type: Correction Published on:

    The original article was published in Stem Cell Research & Therapy 2018 9:190

  34. Glioma, which accounts for more than 30% of primary central nervous system tumours, is characterised by symptoms such as headaches, epilepsy, and blurred vision. Glioblastoma multiforme is the most aggressive,...

    Authors: Qing Zhang, Wei Xiang, Dong-ye Yi, Bing-zhou Xue, Wan-wan Wen, Ahmed Abdelmaksoud, Nan-xiang Xiong, Xiao-bing Jiang, Hong-yang Zhao and Peng Fu
    Citation: Stem Cell Research & Therapy 2018 9:228
    Content type: Review Published on:

  37. Acute kidney injury (AKI) remains a worldwide public health issue due to its increasing incidence, significant mortality, and lack of specific target-orientated therapy. Developments in mesenchymal stem cell (...

    Authors: Lingfei Zhao, Chenxia Hu, Ping Zhang, Hua Jiang and Jianghua Chen
    Citation: Stem Cell Research & Therapy 2018 9:225
    Content type: Review Published on:

  38. Nicotinamide adenine dinucleotide (NAD+) is a critical molecule involved in various biological functions. Poly (ADP-ribose) polymerase 1 (PARP1) and sirtuin 1 (SIRT1) affect cellular NAD+ levels and play essentia...

    Authors: Siyuan Zha, Zhen Li, Qing Cao, Fei Wang and Fang Liu
    Citation: Stem Cell Research & Therapy 2018 9:224
    Content type: Research Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2018 9:269

  39. Deep vein thrombosis (DVT) is caused by blood clotting in the deep veins. Thrombosis resolution and recanalization can be accelerated by endothelial progenitor cells. In this report, we investigated the effect...

    Authors: Jiacheng Sun, Zhiwei Zhang, Teng Ma, Ziying Yang, Jinlong Zhang, Xuan Liu, Da Lu, Zhenya Shen, Junjie Yang and Qingyou Meng
    Citation: Stem Cell Research & Therapy 2018 9:223
    Content type: Research Published on:

    The Retraction Note to this article has been published in Stem Cell Research & Therapy 2019 10:162

  40. The original article [1] contained a small typo affecting the co-author, Mohammed Al-Hawwas’s name. This error has now been corrected.

    Authors: Nimshitha Pavathuparambil Abdul Manaph, Mohammed Al-Hawwas, Larisa Bobrovskaya, Patrick T. Coates and Xin-Fu Zhou
    Citation: Stem Cell Research & Therapy 2018 9:222
    Content type: Correction Published on:

    The original article was published in Stem Cell Research & Therapy 2018 9:189

  41. Tooth agenesis, one of the most common developmental anomalies, can affect the function and esthetics of patients. The aim of the present study was to identify genetic clues for familial tooth agenesis and exp...

    Authors: Tianyi Xin, Ting Zhang, Qian Li, Tingting Yu, Yunyan Zhu, Ruili Yang and Yanheng Zhou
    Citation: Stem Cell Research & Therapy 2018 9:221
    Content type: Research Published on:

  42. Mesenchymal stromal cell (MSC)-based therapy is a promising strategy for preventing the progression of chronic kidney disease (CKD), with the potential to induce tissue regeneration. In search of the best cell...

    Authors: Cinzia Rota, Marina Morigi, Domenico Cerullo, Martino Introna, Ornella Colpani, Daniela Corna, Chiara Capelli, Ton J. Rabelink, Danielle G. Leuning, Daniela Rottoli, Ariela Benigni, Carlamaria Zoja and Giuseppe Remuzzi
    Citation: Stem Cell Research & Therapy 2018 9:220
    Content type: Research Published on:

  43. Irradiation-induced kidney damage is inevitable during radiotherapeutic practice, which limits effective radiotherapy doses on tumor treatment. In the present study, the role of mTOR complex 1 (mTORC1) signali...

    Authors: Lijian Shao, Wuping Yang, Rui Xu, Shuqin Zhu, Yanqiu Huang, Huan Li, Xincheng Wu, Mengzhen Yue, Xiaoliang Xiong, Xiaowen Chen, Bohai Kuang, Guangqin Fan, Qingxian Zhu and Huihong Zeng
    Citation: Stem Cell Research & Therapy 2018 9:219
    Content type: Research Published on:

  45. Skin is an organ that plays an important role as a physical barrier and has many other complex functions. Skin mimetics may be useful for studying the pathophysiology of diseases in vitro and for repairing les...

    Authors: Yena Kim, Narae Park, Yeri Alice Rim, Yoojun Nam, Hyerin Jung, Kijun Lee and Ji Hyeon Ju
    Citation: Stem Cell Research & Therapy 2018 9:217
    Content type: Research Published on:

  46. Although many reports show that various kinds of stem cells have the ability to recover the function of premature ovarian insufficiency (POI), few studies are associated with the mechanism of stem cell treatme...

    Authors: Boxian Huang, Jiafeng Lu, Chenyue Ding, Qinyan Zou, Wei Wang and Hong Li
    Citation: Stem Cell Research & Therapy 2018 9:216
    Content type: Research Published on:

  47. Several studies have confirmed that gold nanoparticles (AuNPs) of specific concentration and size exert a boosting effect on cell proliferation; however, the mechanism through which this effect occurs remains ...

    Authors: Chen Li, Zhuoquan Li, Yan Zhang, Abdel Hamid Fathy and Min Zhou
    Citation: Stem Cell Research & Therapy 2018 9:214
    Content type: Research Published on:

  48. Adipose-derived mesenchymal stem cells (ADSCs) have been extensively explored as a promising therapeutic agent due to their differentiation, proliferation and migration abilities. The epigenetic mechanisms tha...

    Authors: Chongyang Shen, Qingli Quan, Chuan Yang, Yueqiang Wen and Hong Li
    Citation: Stem Cell Research & Therapy 2018 9:212
    Content type: Research Published on:

  49. Differentiation of human induced pluripotent stem cells (hiPSCs) into hepatocytes has important clinical significance in providing a new stem cell source for cell therapy of terminal liver disease. The differe...

    Authors: Ziran Xu, Xia He, Xu Shi, Yuhan Xia, Xiaomei Liu, Haitao Wu, Pengdong Li, Hongyu Zhang, Weisi Yin, Xiubo Du, Lisha Li and Yulin Li
    Citation: Stem Cell Research & Therapy 2018 9:211
    Content type: Research Published on:

  50. Human endometrial epithelia undergo injury repair and regeneration with the menstrual cycle; however, mechanisms underpinning the roles of endometrial epithelial cells in endometrial lesions and regeneration r...

    Authors: Dandan Li, Hui Li, Ying Wang, Ahmed Eldomany, Jing Wu, Chao Yuan, Jing Xue, Juan Shi, Yuanyuan Jia, Chunfang Ha, Shuxia Han, Xiaoming Liu, Jiali Yang and Dan Liu
    Citation: Stem Cell Research & Therapy 2018 9:209
    Content type: Short report Published on:
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