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  1. Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide. Specific and thorough identification of cancer cell subsets with higher tumorigenicity and chemoresistance, such as cancer stem cells ...

    Authors: Angel A. Gómez-Gallegos, Lizbeth Ramírez-Vidal, Jared Becerril-Rico, Elizabeth Pérez-Islas, Zuly J. Hernandez-Peralta, Mariel E. Toledo-Guzmán, Alejandro García-Carrancá, Elizabeth Langley, Angélica Hernández-Guerrero, Fernando López-Casillas, Roberto Herrera-Goepfert, Luis F. Oñate-Ocaña and Elizabeth Ortiz-Sánchez
    Citation: Stem Cell Research & Therapy 2023 14:16
    Content type: Research Published on:

  2. A growing number of investigations have suggested a close link between cancer stem cells (CSCs), epithelial-to-mesenchymal transition (EMT), and the tumor microenvironment (TME). However, the relationships bet...

    Authors: Yanlong Zhang, Xin Zhang, Xuefeng Huang, Xiaomeng Tang, Menghan Zhang, Ziyi Li, Xiaopeng Hu, Min Zhang, Xi Wang and Yong Yan
    Citation: Stem Cell Research & Therapy 2023 14:15
    Content type: Research Published on:

  3. Mesenchymal stromal cells (MSCs) have attracted great attention in the application of cell-based therapy because of their pluripotent differentiation and immunomodulatory ability. Due to the limited number of ...

    Authors: Kai Lin, Yanlei Yang, Yinghao Cao, Junbo Liang, Jun Qian, Xiaoyue Wang and Qin Han
    Citation: Stem Cell Research & Therapy 2023 14:14
    Content type: Research Published on:

  5. Mesenchymal stem/stromal cells (MSCs) are multipotent cells with strong tissue repair and immunomodulatory properties. Due to their ability to repress pathogenic immune responses, and in particular T cell resp...

    Authors: Waseem Akhter, Jean Nakhle, Loïc Vaillant, Geneviève Garcin, Cécile Le Saout, Matthieu Simon, Carole Crozet, Farida Djouad, Christian Jorgensen, Marie-Luce Vignais and Javier Hernandez
    Citation: Stem Cell Research & Therapy 2023 14:12
    Content type: Research Published on:

  6. Hypoimmunogenic human pluripotent stem cells (hPSCs) are expected to serve as an unlimited cell source for generating universally compatible “off-the-shelf” cell grafts. However, whether the engineered hypoimm...

    Authors: Yifan Chen, Yanjie Zhou, Zhongshu Zhou, Yujiang Fang, Lin Ma, Xiaoqing Zhang, Jie Xiong and Ling Liu
    Citation: Stem Cell Research & Therapy 2023 14:11
    Content type: Short report Published on:

  7. Mesenchymal stromal cell (MSC) transplantation therapy is a promising therapy for stroke patients. In parallel, rehabilitation with physical exercise could ameliorate stroke-induced neurological impairment. In...

    Authors: Satoru Yabuno, Takao Yasuhara, Takayuki Nagase, Satoshi Kawauchi, Chiaki Sugahara, Yosuke Okazaki, Kakeru Hosomoto, Susumu Sasada, Tatsuya Sasaki, Naoki Tajiri, Cesar V. Borlongan and Isao Date
    Citation: Stem Cell Research & Therapy 2023 14:10
    Content type: Research Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2023 14:123

  10. Bone tissue engineering (BTE) emerged as one of the exceptional means for bone defects owing to it providing mechanical supports to guide bone tissue regeneration. Great advances have been made to facilitate t...

    Authors: Hongqi Zhao, Chaoxu Liu, Yang Liu, Qing Ding, Tianqi Wang, Hao Li, Hua Wu and Tian Ma
    Citation: Stem Cell Research & Therapy 2023 14:7
    Content type: Review Published on:

  11. Multiple sclerosis (MS) is the most frequent non-traumatic neurological debilitating disease among young adults with no cure. Over recent decades, efforts to treat neurodegenerative diseases have shifted to re...

    Authors: Mariam F. Farid, Yara S. Abouelela, Noha A. E. Yasin, Asmaa K. Al-Mokaddem, Abdelbary Prince, Marwa A. Ibrahim and Hamdy Rizk
    Citation: Stem Cell Research & Therapy 2023 14:6
    Content type: Research Published on:

  12. Cellular therapy seems to be an innovative therapeutic alternative for which mesenchymal stem cells (MSCs) have been shown to be effective for interstitial and hemorrhagic cystitis. However, the action of MSCs...

    Authors: Clément Brossard, Anne-Laure Pouliet, Anne‐Charlotte Lefranc, Mohamedamine Benadjaoud, Morgane Dos Santos, Christelle Demarquay, Valerie Buard, Marc Benderitter, Jean-Marc Simon, Fabien Milliat and Alain Chapel
    Citation: Stem Cell Research & Therapy 2023 14:5
    Content type: Research Published on:

  13. Cell therapy is a key technology to prevent sacrificing normal skin. Although some studies have shown the promise of human epidermal stem cells (EpiSCs), the efficacy, biosafety and quality control of EpiSC th...

    Authors: Xiaohong Zhao, Xue Li, Ying Wang, Yicheng Guo, Yong Huang, Dalun Lv, Mingxing Lei, Shicang Yu, Gaoxing Luo and Rixing Zhan
    Citation: Stem Cell Research & Therapy 2023 14:4
    Content type: Research Published on:

  14. Alzheimer’s disease (AD) is a common progressive neurodegenerative disease characterized by memory impairments, and there is no effective therapy. Neural stem/progenitor cell (NSPC) has emerged as potential no...

    Authors: Zijing Zhou, Ben Shi, Yaxing Xu, Jinyu Zhang, Xin liu, Xinghong Zhou, Baofeng Feng, Jun Ma and Huixian Cui
    Citation: Stem Cell Research & Therapy 2023 14:3
    Content type: Review Published on:

  15. Traumatic brain injury (TBI) is a disease with high mortality and morbidity, which leads to severe neurological dysfunction. Neurogenesis has provided therapeutic options for treating TBI. Brain derived neurot...

    Authors: Na Wu, Xiaochuan Sun, Chao Zhou, Jin Yan and Chongjie Cheng
    Citation: Stem Cell Research & Therapy 2023 14:2
    Content type: Research Published on:

  16. Transplantation of differentiated cells from human-induced pluripotent stem cells (hiPSCs) holds great promise for clinical treatments. Eliminating the risk factor of malignant cell transformation is essential...

    Authors: Kensuke Sakuma, Noriko Tsubooka-Yamazoe, Kiyohiro Hashimoto, Nozomu Sakai, Shinya Asano, Saori Watanabe-Matsumoto, Takeshi Watanabe, Bunnai Saito, Hirokazu Matsumoto, Hikaru Ueno, Ryo Ito and Taro Toyoda
    Citation: Stem Cell Research & Therapy 2023 14:1
    Content type: Research Published on:

  18. BMP9-stimulated DPSCs, SCAPs and PDLSCs are effective candidates for repairing maxillofacial bone defects in tissue engineering, while the most suitable seed cell source among these three hDMSCs and the optima...

    Authors: Yuxin Zhang, Wenping Luo, Liwen Zheng, Jing Hu, Li Nie, Huan Zeng, Xi Tan, Yucan Jiang, Yeming Li, Tianyu Zhao, Zhuohui Yang, Tong-Chuan He and Hongmei Zhang
    Citation: Stem Cell Research & Therapy 2022 13:535
    Content type: Research Published on:

  19. Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2 (MECP2), is one of the most prevalent neurodevelopmental disorders in girls. However, the underlying mechanism of MECP2 remains l...

    Authors: Ya-Jie Xu, Pei-Pei Liu, Zhong-Ze Yan, Ting-Wei Mi, Ying-Ying Wang, Qian Li, Zhao-Qian Teng and Chang-Mei Liu
    Citation: Stem Cell Research & Therapy 2022 13:534
    Content type: Research Published on:

  20. Bone marrow mesenchymal stromal cells (BMSCs) are promising for therapeutic use in cartilage repair, because of their capacity to differentiate into chondrocytes. Often, in vitro differentiation protocols empl...

    Authors: Daniele Zuncheddu, Elena Della Bella, Dalila Petta, Cecilia Bärtschi, Sonja Häckel, Moritz C. Deml, Martin J. Stoddart, Sibylle Grad and Valentina Basoli
    Citation: Stem Cell Research & Therapy 2022 13:533
    Content type: Research Published on:

  21. Sprouting angiogenesis is an important mechanism for morphogenetic phenomena, including organ development, wound healing, and tissue regeneration. In regenerative medicine, therapeutic angiogenesis is a clinic...

    Authors: Takanori Sano, Tadaaki Nakajima, Koharu Alicia Senda, Shizuka Nakano, Mizuho Yamato, Yukinori Ikeda, Hedele Zeng, Jun-ichi Kawabe and Yukiko T. Matsunaga
    Citation: Stem Cell Research & Therapy 2022 13:532
    Content type: Research Published on:

  22. Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (iPSC-CMs) do not display all hallmarks of mature primary cardiomyocytes, especially the ability to use fatty acids (FA) as an energy source, c...

    Authors: Nino Chirico, Elise L. Kessler, Renée G. C. Maas, Juntao Fang, Jiabin Qin, Inge Dokter, Mark Daniels, Tomo Šarić, Klaus Neef, Jan-Willem Buikema, Zhiyong Lei, Pieter A. Doevendans, Joost P. G. Sluijter and Alain van Mil
    Citation: Stem Cell Research & Therapy 2022 13:531
    Content type: Research Published on:

  23. Authors: Rongchuan Yue, Wenbin Fu, Xiang Liao, Cong Lan, Qiao Liao, Liangpeng Li, Dezhong Yang, Xuewei Xia, Xiongwen Chen, Chunyu Zeng and Wei Eric Wang
    Citation: Stem Cell Research & Therapy 2022 13:530
    Content type: Correction Published on:

    The original article was published in Stem Cell Research & Therapy 2017 8:17

  24. Tissue organoids generated from human pluripotent stem cells are valuable tools for disease modelling and to understand developmental processes. While recent progress in human cardiac organoids revealed the ab...

    Authors: Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin-Han Loh, Omer An, Henry He Yang, Veerabrahma Pratap Seshachalam, Judice L. Y. Koh, Woon-Khiong Chan, Shi Yan Ng and Boon Seng Soh
    Citation: Stem Cell Research & Therapy 2022 13:529
    Content type: Research Published on:

  25. Nowadays, diabetes mellitus is known as a silent killer because individual is not aware that he has the disease till the development of its complications. Many researchers have studied the use of stem cells in...

    Authors: Alyaa Farid, Hebatallah Haridyy, Salma Ashraf, Selim Ahmed and Gehan Safwat
    Citation: Stem Cell Research & Therapy 2022 13:528
    Content type: Research Published on:

  26. Brain tumors are one of the most mortal cancers, leading to many deaths among kids and adults. Surgery, chemotherapy, and radiotherapy are available options for brain tumor treatment. However, these methods ar...

    Authors: Elham Ghasempour, Shilan Hesami, Elaheh Movahed, Saeed Heidari keshel and Mohammad Doroudian
    Citation: Stem Cell Research & Therapy 2022 13:527
    Content type: Review Published on:

  28. The effects of traumatic brain injury (TBI) can include physical disability and even death. The development of effective therapies to promote neurological recovery is still a challenging problem. 3D-printed bi...

    Authors: Xiao-Yin Liu, Zhe-Han Chang, Chong Chen, Jun Liang, Jian-Xin Shi, Xiu Fan, Qi Shao, Wei-Wei Meng, Jing-Jing Wang and Xiao-Hong Li
    Citation: Stem Cell Research & Therapy 2022 13:525
    Content type: Research Published on:

  30. Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by muscu...

    Authors: Łukasz Pulik, Bartosz Mierzejewski, Aleksandra Sibilska, Iwona Grabowska, Maria Anna Ciemerych, Paweł Łęgosz and Edyta Brzóska
    Citation: Stem Cell Research & Therapy 2022 13:523
    Content type: Review Published on:

  32. MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules encoded by endogenous genes, which play a vital role in cell generation, metabolism, apoptosis and stem cell differentiation. C3H10T1/2, a mesenc...

    Authors: Wei Huang, Xiaoyue Wu, Shuaixi Xiang, Mingxin Qiao, Hanfei Li, Yujie Zhu, Zhou Zhu and Zhihe Zhao
    Citation: Stem Cell Research & Therapy 2022 13:521
    Content type: Review Published on:

  34. Mesenchymal stem cells (MSCs) driven gene directed enzyme prodrug therapy is a promising approach to deliver therapeutic agents to target heterogenous solid tumours. To democratize such a therapy, cryopreserva...

    Authors: Yoon Khei Ho, Kin Man Loke, Jun Yung Woo, Yee Lin Lee and Heng-Phon Too
    Citation: Stem Cell Research & Therapy 2022 13:519
    Content type: Research Published on:

  35. Bone-related diseases are major contributors to morbidity and mortality in elderly people and the current treatments result in insufficient healing and several complications. One of the promising areas of rese...

    Authors: Armin Ahmadi, Radman Mazloomnejad, Mohammadreza Kasravi, Babak Gholamine, Soheyl Bahrami, Mohammad Mahdi Sarzaeem and Hassan Niknejad
    Citation: Stem Cell Research & Therapy 2022 13:518
    Content type: Review Published on:

  36. Human umbilical cord mesenchymal stem cells (hUC-MSCs) are increasingly being studied in clinical trials of end-stage liver disease because of their good tissue repair and anti-inflammatory effects. hUC-MSC ex...

    Authors: Ying Shi, Xiaoguang Yang, Shuyue Wang, Yulun Wu, Lihua Zheng, Yufang Tang, Yanhang Gao and Junqi Niu
    Citation: Stem Cell Research & Therapy 2022 13:517
    Content type: Research Published on:

  37. Endothelial progenitor cells (EPCs) contribute to the recovery of neurological function after ischemic stroke. Indirect revascularization has exhibited promising effects in the treatment of cerebral ischemia r...

    Authors: Kuo-Chuan Wang, Ling-Yu Yang, Jing-Er Lee, Vicent Wu, Te-Fu Chen, Sung-Tsang Hsieh and Meng-Fai Kuo
    Citation: Stem Cell Research & Therapy 2022 13:516
    Content type: Research Published on:

  38. Tendon regeneration is difficult because detailed knowledge about tendon progenitor cells (TPCs), which produce tenocytes to repair tendon tissue, has not been revealed. Mohawk homeobox (MKX) is a marker of TP...

    Authors: Yuki Fujisawa, Lu Ming, Daisuke Yamada, Tomoka Takao and Takeshi Takarada
    Citation: Stem Cell Research & Therapy 2022 13:515
    Content type: Short report Published on:

  41. The mesenchymal stem cells (MSCs) were used to repair tissue injury. However, the treatment effect was not satisfactory. We investigated whether lncRNA MIR155HG could promote survival and migration of MSCs und...

    Authors: Xiao Bai, Zaiwen Qi, Mingzhen Zhu, Zhuangzhuang Lu, Xin Zhao, Lining Zhang and Guangmin Song
    Citation: Stem Cell Research & Therapy 2022 13:512
    Content type: Research Published on:

  42. Bone injury plagues millions of patients worldwide every year, and it demands a heavy portion of expense from the public medical insurance system. At present, orthopedists think that autologous bone transplant...

    Authors: Yu-Hao Wang, Cheng-Zhi Zhao, Ren-Yi Wang, Qian-Xin Du, Ji-Yuan Liu and Jian Pan
    Citation: Stem Cell Research & Therapy 2022 13:511
    Content type: Review Published on:

    The Correction to this article has been published in Stem Cell Research & Therapy 2022 13:524

  46. Mesenchymal stem cells (MSCs) have shown immense therapeutic potential for various brain diseases. Intrathecal administration of MSCs may enhance their recruitment to lesions in the central nervous system, but...

    Authors: Ye Ran, Yankai Dong, Yuejiao Li, Jundong Xie, Shubin Zeng, Chuanlei Liang, Wei Dai, Wenjing Tang, Yaojiong Wu and Shengyuan Yu
    Citation: Stem Cell Research & Therapy 2022 13:507
    Content type: Research Published on:

  48. Authors: Qin He, Lingshu Wang, Ruxing Zhao, Fei Yan, Sha Sha, Chen Cui, Jia Song, Huiqing Hu, Xinghong Guo, Mengmeng Yang, Yixin Cui, Yujing Sun, Zheng Sun, Fuqiang Liu, Ming Dong, Xinguo Hou…
    Citation: Stem Cell Research & Therapy 2022 13:505
    Content type: Retraction Note Published on:

  50. Cell-based therapy using adipose-derived mesenchymal stem cells (ADSCs) is a promising treatment strategy for neurogenic bladder (NB) associated with spinal cord injury (SCI). However, therapeutic efficacy is ...

    Authors: Jiasheng Chen, Lin Wang, Meng Liu, Guo Gao, Weixin Zhao, Qiang Fu and Ying Wang
    Citation: Stem Cell Research & Therapy 2022 13:503
    Content type: Research Published on:
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