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  1. Using a toxin-induced nonhuman primate model of acute liver failure (ALF), we previously reported that peripheral infusion of human umbilical cord mesenchymal stem cells (hUC-MSCs) strongly suppresses the acti...

    Authors: Mingyang Shao, Qing Xu, Zhenru Wu, Yuwei Chen, Yuke Shu, Xiaoyue Cao, Menglin Chen, Bo Zhang, Yongjie Zhou, Rong Yao, Yujun Shi and Hong Bu

    Citation: Stem Cell Research & Therapy 2020 11:37

    Content type: Research

    Published on:

  2. A growing body of evidence suggests that stem cell-derived exosomal microRNAs (miRNAs) could be a promising cardioprotective therapy in the context of hypoxic conditions. The present study aims to explore how ...

    Authors: Zhuzhi Wen, Zun Mai, Xiaolin Zhu, Tao Wu, Yangxin Chen, Dengfeng Geng and Jingfeng Wang

    Citation: Stem Cell Research & Therapy 2020 11:36

    Content type: Research

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  3. Adipose-derived stem cell (ASC) expansion under atmospheric oxygen levels (21%) was previously shown to cause increased reactive oxygen species (ROS) accumulation and genetic instability compared to cells cult...

    Authors: Gal Tirza, Inna Solodeev, Meirav Sela, Ilanit Greenberg, Metsada Pasmanik-Chor, Eyal Gur and Nir Shani

    Citation: Stem Cell Research & Therapy 2020 11:35

    Content type: Research

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  4. Vascularization is important for the clinical application of tissue engineered products. Both adipose-derived stem cells (ASCs) and surgical prefabrication can be used to induce angiogenesis in scaffolds. Our ...

    Authors: Tomasz Dębski, Agata Kurzyk, Barbara Ostrowska, Juliusz Wysocki, Jakub Jaroszewicz, Wojciech Święszkowski and Zygmunt Pojda

    Citation: Stem Cell Research & Therapy 2020 11:34

    Content type: Research

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  5. The original article [1] contains an error in Fig. 5 whereby sub-Fig. 5c, d & 5e are mistakenly mixed-up.

    Authors: Rui Zuo, Minghan Liu, Yanqiu Wang, Jie Li, Wenkai Wang, Junlong Wu, Chao Sun, Bin Li, Ziwen Wang, Weiren Lan, Chao Zhang, Chunmeng Shi and Yue Zhou

    Citation: Stem Cell Research & Therapy 2020 11:33

    Content type: Correction

    Published on:

    The original article was published in Stem Cell Research & Therapy 2019 10:30

  6. Mesenchymal stem cells (MSCs) hold great potential as a therapy for stroke and have previously been shown to promote recovery in preclinical models of cerebral ischaemia. MSCs secrete a wide range of growth fa...

    Authors: Catriona J. Cunningham, Raymond Wong, Jack Barrington, Sabrina Tamburrano, Emmanuel Pinteaux and Stuart M. Allan

    Citation: Stem Cell Research & Therapy 2020 11:32

    Content type: Research

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  7. Extracellular vesicles, especially exosomes, have emerged as key mediators of intercellular communication with the potential to improve cardiac function as part of cell-based therapies. We previously demonstra...

    Authors: Hanbin Chen, Wenzheng Xia and Meng Hou

    Citation: Stem Cell Research & Therapy 2020 11:31

    Content type: Research

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  8. Preeclampsia is a common obstetric syndrome affecting women in their first pregnancy and characterized by hypertension and proteinuria, which appears after 20 weeks of gestation. It is characterized by high bl...

    Authors: Yasser S. Basmaeil, Dana Algudiri, Reem Alenzi, Abdullah Al Subayyil, Ayodele Alaiya and Tanvir Khatlani

    Citation: Stem Cell Research & Therapy 2020 11:30

    Content type: Research

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  9. Mesenchymal stem cells (MSCs) secrete a cocktail of growth factors and cytokines, which could promote tissue regeneration and wound healing. Therefore, in clinical practice, post-culture MSC supernatant treatm...

    Authors: Honorata Kraskiewicz, Maria Paprocka, Aleksandra Bielawska-Pohl, Agnieszka Krawczenko, Kinga Panek, Judyta Kaczyńska, Agnieszka Szyposzyńska, Mateusz Psurski, Piotr Kuropka and Aleksandra Klimczak

    Citation: Stem Cell Research & Therapy 2020 11:29

    Content type: Research

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  10. Endothelial progenitor cells (EPCs) contribute to reendothelialization and neovascularization and protect against vascular injury and ischemia of various organs. We have previously shown downregulation of micr...

    Authors: Chong Zhe Pei, Bo Liu, Ye Ting Li, Lu Fang, Yi Zhang, Yi Gang Li and Shu Meng

    Citation: Stem Cell Research & Therapy 2020 11:28

    Content type: Research

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  11. Vitiligo is an acquired chronic and recurrent skin disease that causes a depigmentation disorder, resulting in selective destruction of melanocytes (MC). However, the mechanism that leads to melanocyte dysfunc...

    Authors: Lifei Zhu, Xi Lin, Lin Zhi, Yushan Fang, Keming Lin, Kai Li and Liangcai Wu

    Citation: Stem Cell Research & Therapy 2020 11:26

    Content type: Research

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  12. Mesenchymal stem cells (MSCs) are a population of pluripotent cells that might be used for treatment of liver disease. However, the efficacy of MSCs for mice with alcoholic hepatitis (AH) and its underlying me...

    Authors: Yue-Meng Wan, Zhi-qiang Li, Qiong Zhou, Chang Liu, Men-Jie Wang, Hui-Xin Wu, Yun-Zhen Mu, Yue-Feng He, Yuan Zhang, Xi-Nan Wu, Yu-Hua Li, Zhi-Yuan Xu, Hua-Mei Wu, Ying Xu, Jin-Hui Yang and Xiao-Fang Wang

    Citation: Stem Cell Research & Therapy 2020 11:24

    Content type: Research

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  13. Bone marrow mesenchymal stem cell (BMSC) transplantation represents a promising therapeutic strategy for ischemic heart disease. However, its effects are hampered by the poor viability of transplanted cells an...

    Authors: Mingzhuo Lin, Xinyue Liu, Haoxiao Zheng, Xiaohui Huang, Yu Wu, Anqing Huang, Hailan Zhu, Yunzhao Hu, Weiyi Mai and Yuli Huang

    Citation: Stem Cell Research & Therapy 2020 11:22

    Content type: Research

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  14. Accumulating evidence shows that mesenchymal stem cells (MSCs) have the potential as a cellular therapy avenue for schistosome-induced liver injury. Extracellular vesicles (EVs) are membranous vesicles release...

    Authors: Liyang Dong, Yanan Pu, Xiaojun Chen, Xin Qi, Lina Zhang, Lei Xu, Wei Li, Yongbin Ma, Sha Zhou, Jifeng Zhu, Yalin Li, Xuefeng Wang and Chuan Su

    Citation: Stem Cell Research & Therapy 2020 11:21

    Content type: Research

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  15. Stem cell-derived sheet engineering has been developed as the next-generation treatment for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem cell transplantation and s...

    Authors: Rui Guo, Masatoshi Morimatsu, Tian Feng, Feng Lan, Dehua Chang, Feng Wan and Yunpeng Ling

    Citation: Stem Cell Research & Therapy 2020 11:19

    Content type: Review

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  16. Profound skeletal muscle wasting and weakness is common after severe burn and persists for years after injury contributing to morbidity and mortality of burn patients. Currently, no ideal treatment exists to i...

    Authors: Yusef Yousuf, Andrea Datu, Ben Barnes, Saeid Amini-Nik and Marc G. Jeschke

    Citation: Stem Cell Research & Therapy 2020 11:18

    Content type: Research

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  17. Neonatal ventilation exacerbates brain injury in lambs with fetal growth restriction (FGR), characterized by neuroinflammation and reduced blood-brain barrier integrity, which is normally maintained by the neu...

    Authors: Atul Malhotra, Margie Castillo-Melendez, Beth J. Allison, Amy E. Sutherland, Ilias Nitsos, Yen Pham, Courtney A. McDonald, Michael C. Fahey, Graeme R. Polglase, Graham Jenkin and Suzanne L. Miller

    Citation: Stem Cell Research & Therapy 2020 11:17

    Content type: Research

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  18. Toll-like receptor 4 (TLR4) ligands such as lipopolysaccharide (LPS) activate immunomodulatory functions and the migration of human mesenchymal stromal cells (hMSCs). Here, we study the migration-related gene ...

    Authors: Sun Hwa Kim, Hae In Choi, Mi Ran Choi, Ga Yeong An, Bert Binas, Kyoung Hwa Jung and Young Gyu Chai

    Citation: Stem Cell Research & Therapy 2020 11:16

    Content type: Research

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  19. In Asherman’s syndrome (AS), intrauterine scarring and fibrotic adhesions lead to menstrual disorders, pregnancy loss, or infertility. A few clinical trials have piloted cell therapy to overcome AS. Understand...

    Authors: Suzanna Queckbörner, Elisabeth Syk Lundberg, Kristina Gemzell-Danielsson and Lindsay C. Davies

    Citation: Stem Cell Research & Therapy 2020 11:15

    Content type: Research

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  20. Persistent epithelial defects (PED), associated with limbal stem cell deficiency (LSCD), require ocular surface reconstruction with a stable corneal epithelium (CE). This study investigated CE reformation usin...

    Authors: Francisco Bandeira, Tze-Wei Goh, Melina Setiawan, Gary Hin-Fai Yam and Jodhbir S. Mehta

    Citation: Stem Cell Research & Therapy 2020 11:14

    Content type: Research

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  21. This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added.

    Authors: Juan Fafián-Labora, Miriam Morente-López, María José Sánchez-Dopico, Onno J. Arntz, Fons A. J. van de Loo, Javier De Toro and María C. Arufe

    Citation: Stem Cell Research & Therapy 2020 11:13

    Content type: Research

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  22. Osteogenic differentiation of bone mesenchymal stem cells (BMSCs) is regulated by numerous signaling pathways. Dopamine (DA), a neurotransmitter, has previously been demonstrated to induce new bone formation b...

    Authors: Chen-Xi Wang, Xi-Yuan Ge, Ming-Yue Wang, Ting Ma, Yu Zhang and Ye Lin

    Citation: Stem Cell Research & Therapy 2020 11:12

    Content type: Research

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  23. Extracellular vesicles (EVs), especially stem cell-derived EVs, have emerged as a potential novel therapy for acute kidney injury (AKI). However, their effects remain incompletely understood. Therefore, we per...

    Authors: Chao Liu, Jin Wang, Jie Hu, Bo Fu, Zhi Mao, Hengda Zhang, Guangyan Cai, Xiangmei Chen and Xuefeng Sun

    Citation: Stem Cell Research & Therapy 2020 11:11

    Content type: Research

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  24. To explore the effect of aerobic training (AT), resistance training (RT) or a combination of AT and RT (AT+RT) on the function of endothelial progenitor cells (EPCs) in mice with type 2 diabetes and the potent...

    Authors: Lu Zhai, Yuhua Liu, Wenpiao Zhao, Qingyun Chen, Tao Guo, Wei Wei, Zhuchun Luo, Yanfeng Huang, Cui Ma, Feng Huang and Xia Dai

    Citation: Stem Cell Research & Therapy 2020 11:10

    Content type: Research

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  25. The recent concept of secretome-based tissue regeneration has profoundly altered the field of regenerative medicine and offers promising novel therapeutic options. In contrast to medicinal products with a sing...

    Authors: Maria Laggner, Alfred Gugerell, Christiane Bachmann, Helmut Hofbauer, Vera Vorstandlechner, Marcus Seibold, Ghazaleh Gouya Lechner, Anja Peterbauer, Sibylle Madlener, Svitlana Demyanets, Dirk Sorgenfrey, Tobias Ostler, Michael Erb, Michael Mildner and Hendrik Jan Ankersmit

    Citation: Stem Cell Research & Therapy 2020 11:9

    Content type: Research

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  26. The functions of HULC have been demonstrated in several cancers. However, its mechanism has not been elucidated in human liver cancer stem cells.

    Authors: Chen Wang, Xiaoxue Jiang, Xiaonan Li, Shuting Song, Qiuyu Meng, Liyan Wang, Yanan Lu, Xiaoru Xin, Hu Pu, Xin Gui, Tianming Li and Dongdong Lu

    Citation: Stem Cell Research & Therapy 2020 11:8

    Content type: Research

    Published on:

  27. Adult human pancreatic beta cells are the “gold standard” for studies on diabetes pathogenesis, but their use is limited by insufficient availability and variable quality. An important effort has recently take...

    Authors: Stéphane Demine, Andrea Alex Schiavo, Sandra Marín-Cañas, Piero Marchetti, Miriam Cnop and Decio L. Eizirik

    Citation: Stem Cell Research & Therapy 2020 11:7

    Content type: Research

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  28. Continuous low-intensity ultrasound (cLIUS) facilitates the chondrogenic differentiation of human mesenchymal stromal cells (MSCs) in the absence of exogenously added transforming growth factor-beta (TGFβ) by ...

    Authors: Neety Sahu, Gaurav Budhiraja and Anuradha Subramanian

    Citation: Stem Cell Research & Therapy 2020 11:6

    Content type: Research

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  29. Periodontal ligament stromal cells (PDLSCs) are ideal cell sources for periodontal tissue repair and regeneration, but little is known about what determines their osteogenic capacity. Long non-coding RNAs (lnc...

    Authors: Yiping Huang, Yineng Han, Runzhi Guo, Hao Liu, Xiaobei Li, Lingfei Jia, Yunfei Zheng and Weiran Li

    Citation: Stem Cell Research & Therapy 2020 11:5

    Content type: Research

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  30. Progressive loss of cell functionality caused by an age-related impairment in cell metabolism concerns not only mature specialized cells but also its progenitors, which significantly reduces their regenerative...

    Authors: Michalina Alicka, Katarzyna Kornicka-Garbowska, Katarzyna Kucharczyk, Martyna Kępska, Michael Rӧcken and Krzysztof Marycz

    Citation: Stem Cell Research & Therapy 2020 11:4

    Content type: Research

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  31. Premature ovarian failure (POF) has a great impact on reproductive endocrine function in females, and it is an important cause of infertility. Previous studies have demonstrated that small extracellular vesicl...

    Authors: Mengyu Liu, Yu Qiu, Zhuowei Xue, Ruoyu Wu, Jie Li, Xin Niu, Ji Yuan, Yang Wang and Qingkai Wu

    Citation: Stem Cell Research & Therapy 2020 11:3

    Content type: Research

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  32. ALI/ARDS is the major cause of acute respiratory failure in critically ill patients. As human chorionic villi-derived MSCs (hCMSCs) could attenuate ALI in the airway injury model, and liraglutide, glucagon-lik...

    Authors: Yun Feng, Linlin Wang, Xiaoying Ma, Xiaotong Yang, Ocholi Don, Xiaoyan Chen, Jieming Qu and Yuanlin Song

    Citation: Stem Cell Research & Therapy 2020 11:2

    Content type: Research

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  33. Human placenta-derived mesenchymal stem cells (PD-MSCs) are powerful sources for cell therapy in regenerative medicine. However, a limited lifespan by senescence through mechanisms that are well unknown is the...

    Authors: Jin Seok, Hyun Sook Jung, Sohae Park, Jung Ok Lee, Chong Jai Kim and Gi Jin Kim

    Citation: Stem Cell Research & Therapy 2020 11:1

    Content type: Research

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  34. Mesenchymal stem cells (MSCs) play a crucial role in maintaining the dynamic balance of bone metabolism. Melatonin may have a regulatory effect on bone metabolism by regulating the lineage commitment and diffe...

    Authors: Tianyuan Jiang, Chao Xia, Xiaoting Chen, Yan Hu, Yan Wang, Jin Wu, Shuyan Chen and Yanhong Gao

    Citation: Stem Cell Research & Therapy 2019 10:408

    Content type: Research

    Published on:

  35. Imbalance in bone formation and resorption is a crucial component of the pathological process leading to osteoporosis. Electromagnetic fields (EMFs) have been reported to be beneficial to osteogenesis, althoug...

    Authors: Yingchi Zhang, Wenkai Li, Chaoxu Liu, Jiyuan Yan, Xuefeng Yuan, Wei Wang, Huaixi Wang, Hua Wu and Yong Yang

    Citation: Stem Cell Research & Therapy 2019 10:407

    Content type: Research

    Published on:

  36. Menstrual blood-derived stem cells (MenSCs) have great potential in the treatment of various diseases. As a novel type of mesenchymal stem cells (MSCs), MenSCs have attracted more interest due to their therape...

    Authors: Lijun Chen, Jingjing Qu, Tianli Cheng, Xin Chen and Charlie Xiang

    Citation: Stem Cell Research & Therapy 2019 10:406

    Content type: Review

    Published on:

  37. Myopathy and exercise intolerance are prominent clinical features in carriers of a point-mutation or large-scale deletion in the mitochondrial DNA (mtDNA). In the majority of patients, the mtDNA mutation is he...

    Authors: Florence van Tienen, Ruby Zelissen, Erika Timmer, Marike van Gisbergen, Patrick Lindsey, Mattia Quattrocelli, Maurilio Sampaolesi, Elvira Mulder-den Hartog, Irenaeus de Coo and Hubert Smeets

    Citation: Stem Cell Research & Therapy 2019 10:405

    Content type: Research

    Published on:

  38. After publication of our article [1] we became aware that there were errors in Fig. 5b and Fig. 6c, namely that the immunofluorescence of EDU-positive cells of the CABLES1 transfection group in Fig. 5b (panel ...

    Authors: Jingjin Liu, Yongshun Wang, Jinjin Cui, Meng Sun, Zhongyue Pu, Chao Wang, Wenjuan Du, Xinxin Liu, Jian Wu, Jingbo Hou, Shuo Zhang and Bo Yu

    Citation: Stem Cell Research & Therapy 2019 10:404

    Content type: Correction

    Published on:

    The original article was published in Stem Cell Research & Therapy 2017 8:127

  39. Billions of dollars are invested annually by pharmaceutical companies in search of new options for treating hair loss conditions; nevertheless, the challenge remains. One major limitation to hair follicle rese...

    Authors: Yiqun Su, Jie Wen, Junrong Zhu, Zhiwei Xie, Chang Liu, Chuan Ma, Qun Zhang, Xin Xu and Xunwei Wu

    Citation: Stem Cell Research & Therapy 2019 10:403

    Content type: Research

    Published on:

  40. Mesenchymal stem cells (MSCs) are multipotent stem cells that are able to differentiate into several cell types, including cartilage, fat, and bone. As a common progenitor, MSC differentiation has to be tightl...

    Authors: Chanchao Lorthongpanich, Kanjana Thumanu, Kantpitchar Tangkiettrakul, Nittaya Jiamvoraphong, Chuti Laowtammathron, Nattaya Damkham, Yaowalak U-pratya and Surapol Issaragrisil

    Citation: Stem Cell Research & Therapy 2019 10:402

    Content type: Research

    Published on:

  41. Emerging evidence suggests that miR-124 performs important biological functions in neural stem cells (NSCs); it regulates NSC behavior and promotes the differentiation of NSCs into neurons, but the exact molec...

    Authors: Yi Cui, Yanyun Yin, Zhifeng Xiao, Yannan Zhao, Bing Chen, Bin Yang, Bai Xu, Hongwei Song, Yunlong Zou, Xu Ma and Jianwu Dai

    Citation: Stem Cell Research & Therapy 2019 10:400

    Content type: Research

    Published on:

  42. Spermatogonial stem cells (SSCs) are the cornerstone of sperm production and thus perpetual male fertility. In clinics, transplantation of patient’s own SSCs into testes is a promising technique to restore fer...

    Authors: Tianjiao Li, Qiwen Chen, Yi Zheng, Pengfei Zhang, Xiaoxu Chen, Junna Lu, Yinghua Lv, Shiguo Sun and Wenxian Zeng

    Citation: Stem Cell Research & Therapy 2019 10:399

    Content type: Research

    Published on:

  43. Aging is one of the dominant factors contributing to erectile dysfunction (ED), and effective treatments for age-associated ED are urgently demanded. In this study, the therapeutic efficiency of bone marrow-de...

    Authors: Qiwei Liu, Yubin Cui, Haojian Lin, Daoyuan Hu, Tao Qi, Bo Wang, Zhansen Huang, Jun Chen, Ke Li and Hengjun Xiao

    Citation: Stem Cell Research & Therapy 2019 10:398

    Content type: Research

    Published on:

  44. Emerging evidence suggests that neural crest-derived cells (NCCs) present important functions in peripheral nerve regeneration to correct the insufficiency of autogenous Schwann cells. Postmigratory NCCs have ...

    Authors: Haiyan Shi, Xiaoli Li, Junling Yang, Yahong Zhao, Chengbin Xue, Yaxian Wang, Qianru He, Mi Shen, Qi Zhang, Yumin Yang and Fei Ding

    Citation: Stem Cell Research & Therapy 2019 10:397

    Content type: Research

    Published on:

  45. Human periodontal ligament stem cells (hPDLSCs) are one of the most promising types of seed cells in periodontal tissue regeneration. Suitable biomaterials are additional essential components that must coopera...

    Authors: Xue Xiong, Xiao Yang, Hongwei Dai, Gang Feng, Yuanyuan Zhang, Jianping Zhou and Wenwen Zhou

    Citation: Stem Cell Research & Therapy 2019 10:396

    Content type: Research

    Published on:

  46. Mesenchymal stromal cells (MSCs), adult stromal cells most commonly isolated from bone marrow (BM), are being increasingly utilized in various therapeutic applications including tissue repair via immunomodulat...

    Authors: Fiorella Rossi, Hunter Noren, Leonor Sarria, Paul C. Schiller, Lubov Nathanson and Vladimir Beljanski

    Citation: Stem Cell Research & Therapy 2019 10:395

    Content type: Research

    Published on:

  47. In athlete horses, suspensory ligament (SL) injuries are the most common cause of lameness. Healing of SL injury is still problematic, and even proper rehabilitation and pharmacological therapy do not guarante...

    Authors: Katarzyna Kornicka-Garbowska, Rafał Pędziwiatr, Paulina Woźniak, Katarzyna Kucharczyk and Krzysztof Marycz

    Citation: Stem Cell Research & Therapy 2019 10:394

    Content type: Short report

    Published on:

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