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  1. Mesenchymal stromal cells (MSCs) tropism for tumours allows their use as carriers of antitumoural factors and in vitro transcribed mRNA (IVT mRNA) is a promising tool for effective transient expression without...

    Authors: María José Cantero, Barbara Bueloni, Lucrecia Gonzalez Llamazares, Esteban Fiore, Lucia Lameroli, Catalina Atorrasagasti, Guillermo Mazzolini, Mariana Malvicini, Juan Bayo and Mariana G. García
    Citation: Stem Cell Research & Therapy 2024 15:208
  2. Vascular tissue engineering is a promising approach for regenerating damaged blood vessels and developing new therapeutic approaches for heart disease treatment. To date, different sources of cells have been r...

    Authors: Mehdi Amiri Goushki, Zahra Kharat, Mousa Kehtari, Alireza Naderi Sohi, Hana Hanaee Ahvaz, Iman Rad, Simzar HosseinZadeh, Fatemeh Kouhkan and Mahboubeh Kabiri
    Citation: Stem Cell Research & Therapy 2024 15:205
  3. Skeletal Stem Cells (SSCs) are required for skeletal development, homeostasis, and repair. The perspective of their wide application in regenerative medicine approaches has supported research in this field, ev...

    Authors: M. L. Schiavone, L. Crisafulli, C. Camisaschi, G. De Simone, F. R. Liberati, E. Palagano, N. Rucci, F. Ficara and Cristina Sobacchi
    Citation: Stem Cell Research & Therapy 2024 15:203
  4. There is no clear evidence on the comparative effectiveness of bone-marrow mononuclear cell (BMMNC) vs. mesenchymal stromal cell (MSC) stem cell therapy in patients with chronic heart failure (HF).

    Authors: Alireza Hosseinpour, Jahangir Kamalpour, Niloofar Dehdari Ebrahimi, Seyed Alireza Mirhosseini, Alireza Sadeghi, Shahin Kavousi and Armin Attar
    Citation: Stem Cell Research & Therapy 2024 15:202
  5. Dysfunction or deficiency of corneal epithelium results in vision impairment or blindness in severe cases. The rapid and effective regeneration of corneal epithelial cells relies on the limbal stem cells (LSCs...

    Authors: Di Sun, Xiaowen Zhang, Rong Chen, Tian Sang, Ya Li, Qun Wang, Lixin Xie, Qingjun Zhou and Shengqian Dou
    Citation: Stem Cell Research & Therapy 2024 15:201
  6. Neural stem cell (NSC) proliferation and differentiation in the mammalian brain decreases to minimal levels postnatally. Nevertheless, neurogenic niches persist in the adult cortex and hippocampus in rodents, ...

    Authors: Despoina Charou, Thanasis Rogdakis, Alessia Latorrata, Maria Valcarcel, Vasileios Papadogiannis, Christina Athanasiou, Alexandros Tsengenes, Maria Anna Papadopoulou, Dimitrios Lypitkas, Matthieu D. Lavigne, Theodora Katsila, Rebecca C. Wade, M. Zameel Cader, Theodora Calogeropoulou, Achille Gravanis and Ioannis Charalampopoulos
    Citation: Stem Cell Research & Therapy 2024 15:200
  7. Bone marrow-derived mesenchymal stem cell (BMMSC)-based therapy has become a major focus for treating liver fibrosis/cirrhosis. However, although these cell therapies promote the treatment of this disease, the he...

    Authors: Deyu Hu, Jiejuan Lai, Quanyu Chen and Lianhua Bai
    Citation: Stem Cell Research & Therapy 2024 15:199
  8. Trans-sutural distraction osteogenesis (TSDO) involves the application of distraction force to facial sutures to stimulate osteogenesis. Gli1+ cells in the cranial sutures play an important role in bone growth. H...

    Authors: Mengying Jin, Yang An, Zheng Wang, Guanhuier Wang, Zhiyu Lin, Pengbing Ding, Enhang Lu, Zhenmin Zhao and Hongsen Bi
    Citation: Stem Cell Research & Therapy 2024 15:198
  9. Traumatic Brain Injury (TBI) represents one of the main causes of brain damage in young people and the elderly population with a very high rate of psycho-physical disability and death. TBI is characterized by ...

    Authors: Francesco Chiani, Valentina Mastrorilli, Nicole Marchetti, Andrea Macioce, Chiara Nappi, Georgios Strimpakos, Miriam Pasquini, Alessia Gambadoro, Jonathan Isacco Battistini, Debora Cutuli, Laura Petrosini, Sara Marinelli, Raffaella Scardigli and Stefano Farioli Vecchioli
    Citation: Stem Cell Research & Therapy 2024 15:197
  10. Over the past decade, we have witnessed the development of cell transplantation as a new strategy for repairing spinal cord injury (SCI). However, due to the complexity of the central nervous system (CNS), ach...

    Authors: Ruoqi Shen, Yubao Lu, Chaoyang Cai, Ziming Wang, Jiayu Zhao, Yingjie Wu, Yinian Zhang and Yang Yang
    Citation: Stem Cell Research & Therapy 2024 15:196
  11. Nowadays, companion and working dogs hold significant social and economic importance. Dry eye, also known as dry keratoconjunctivitis (KCS), a common disease in ophthalmology, can readily impact a dog’s workin...

    Authors: Chenchen Li, Balun Li, Miao Han, Hongkai Tian, Jiaqi Gao, Dongyao Han, Zixi Ling, Yuanxiang Jing, Na Li and Jinlian Hua
    Citation: Stem Cell Research & Therapy 2024 15:195
  12. Repairation of bone defects remains a major clinical problem. Constructing bone tissue engineering containing growth factors, stem cells, and material scaffolds to repair bone defects has recently become a hot...

    Authors: Ying Ji, Yongkang Mao, Honghu Lin, Ye Wang, Peishuai Zhao, Yong Guo, Lantao Gu, Can Fu, Ximiao Chen, Zheng Lv, Ning Wang, Qiang Li and Chaoyong Bei
    Citation: Stem Cell Research & Therapy 2024 15:194
  13. The human induced pluripotent stem cells (hiPSCs) can generate all the cells composing the human body, theoretically. Therefore, hiPSCs are thought to be a candidate source of stem cells for regenerative medic...

    Authors: Norihiro Tsuneyoshi, Tomonori Hosoya, Yuriko Takeno, Kodai Saitoh, Hidetaka Murai, Naoki Amimoto, Rie Tatsumi, Sono Watanabe, Yudai Hasegawa, Eri Kikkawa, Kumiko Goto, Fusako Nishigaki, Kouichi Tamura and Hironobu Kimura
    Citation: Stem Cell Research & Therapy 2024 15:193
  14. Inherited retinal dystrophies (IRD) are one of the main causes of incurable blindness worldwide. IRD are caused by mutations in genes that encode essential proteins for the retina, leading to photoreceptor deg...

    Authors: Kevin Puertas-Neyra, Rosa M. Coco-Martin, Leticia A. Hernandez-Rodriguez, Dino Gobelli, Yenisey Garcia-Ferrer, Raicel Palma-Vecino, Juan José Tellería, Maria Simarro, Miguel A. de la Fuente and Ivan Fernandez-Bueno
    Citation: Stem Cell Research & Therapy 2024 15:192
  15. Stem cell-derived therapies hold the potential for treatment of regenerative clinical indications. Static culture has a limited ability to scale up thus restricting its use. Suspension culturing can be used to...

    Authors: Haneen Yehya, Sofija Raudins, Roshan Padmanabhan, Jan Jensen and Michael A. Bukys
    Citation: Stem Cell Research & Therapy 2024 15:191
  16. Mesenchymal stem cells (MSCs) demonstrate a wide range of therapeutic capabilities in the treatment of inflammatory bowel disease (IBD). The intraperitoneal injection of MSCs has exhibited superior therapeutic...

    Authors: Qixiang Zhang, Zhu Zeng, Ning Wei, Yueyan Su, Jing Wang, Qi Ni, Yukai Wang, Jingwen Yang, Xiaoyan Liu, Huanke Xu, Guangji Wang, Yunlong Shan and Fang Zhou
    Citation: Stem Cell Research & Therapy 2024 15:190
  17. Recent studies have proved the role of autophagy in mesenchymal stem cell (MSCs) function and regenerative properties. How and by which mechanism autophagy modulation can affect the juxtacrine interaction of M...

    Authors: Fatemeh Sadeghsoltani, Çığır Biray Avci, Parisa Hassanpour, Sanya Haiaty, Mohamad Rahmati, Ali Mota, Reza Rahbarghazi, Maryam Nemati, Mahdi Mahdipour, Mehdi Talebi, Leila Sabour Takanlou, Maryam Sabour Takanlou and Amir Mehdizadeh
    Citation: Stem Cell Research & Therapy 2024 15:189
  18. Diabetes mellitus, a significant global public health challenge, severely impacts human health worldwide. The organoid, an innovative in vitro three-dimensional (3D) culture model, closely mimics tissues or or...

    Authors: Yushan Li, Meiqi Xu, Jiali Chen, Jiansong Huang, Jiaying Cao, Huajing Chen, Jiayi Zhang, Yukun Luo, Yazhuo Wang and Jia Sun
    Citation: Stem Cell Research & Therapy 2024 15:188
  19. Due to the advanced studies on stem cells in developmental biology, the roles of stem cells in the body and their phenotypes in related diseases have not been covered clearly. Meanwhile, with the intensive res...

    Authors: Zi-xian Liu, Guan-qiao Liu, Ze-xin Lin, Ying-qi Chen, Peng Chen, Yan-jun Hu, Bin Yu and Nan Jiang
    Citation: Stem Cell Research & Therapy 2024 15:187
  20. Human induced pluripotent stem cells (hiPSCs) and their differentiated cell types have a great potential for tissue repair and regeneration. While the primary focus of using hiPSCs has historically been to reg...

    Authors: Divya Sridharan, Julie A. Dougherty, Uzair Ahmed, Shridhar K. Sanghvi, Syed Baseeruddin Alvi, Ki Ho Park, Helena Islam, Sue E. Knoblaugh, Harpreet Singh, Elizabeth D. Kirby and Mahmood Khan
    Citation: Stem Cell Research & Therapy 2024 15:186
  21. Cartilage, an important connective tissue, provides structural support to other body tissues, and serves as a cushion against impacts throughout the body. Found at the end of the bones, cartilage decreases fri...

    Authors: Eltahir Abdelrazig Mohamed Ali, Rana Smaida, Morgane Meyer, Wenxin Ou, Zongjin Li, Zhongchao Han, Nadia Benkirane-Jessel, Jacques Eric Gottenberg and Guoqiang Hua
    Citation: Stem Cell Research & Therapy 2024 15:185
  22. Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) by traditional methods are a mix of atrial and ventricular CMs and many other non-cardiomyocyte cells. Retinoic acid (RA) plays a...

    Authors: Hengliang Zhang, Payel Sen, Jules Hamers, Theresa Sittig, Brent Woestenburg, Allessandra Moretti, Andreas Dendorfer and Daphne Merkus
    Citation: Stem Cell Research & Therapy 2024 15:184
  23. Human hematopoietic stem cell (HSC)-transferred humanized mice are valuable models for exploring human hematology and immunology. However, sufficient recapitulation of human hematopoiesis in mice requires larg...

    Authors: Ryoji Ito, Yusuke Ohno, Yunmei Mu, Yuyo Ka, Shuko Ito, Maiko Emi-Sugie, Misa Mochizuki, Kenji Kawai, Motohito Goto, Tomoyuki Ogura, Riichi Takahashi, Akira Niwa, Tatsutoshi Nakahata and Mamoru Ito
    Citation: Stem Cell Research & Therapy 2024 15:182
  24. Intrauterine adhesion (IUA) as a prevalent gynecological disease is developed from infection or trauma. However, therapeutic strategies to repair damaged endometrium are relatively limited. Emerging studies ha...

    Authors: Zhengli Zhou, Xiaomei Wu, Tingwei Chen, Bo Zhang, Wenxin Li, Min Zhou, Jingxue Zhao, E. Dong and Tianqing Li
    Citation: Stem Cell Research & Therapy 2024 15:181
  25. Telomeres consist of repetitive DNA sequences at the chromosome ends to protect chromosomal stability, and primarily maintained by telomerase or occasionally by alternative telomere lengthening of telomeres (A...

    Authors: Shuang Zhao, Jie Li, Songqi Duan, Chang Liu, Hua Wang, Jiangtao Lu, Nannan Zhao, Xiaoyan Sheng, Yiwei wu, Yanjun Li, Baofa Sun and Lin Liu
    Citation: Stem Cell Research & Therapy 2024 15:180
  26. Adult skeletal muscle contains resident muscle stem cells (MuSC) with high myogenic and engraftment potentials, making them suitable for cell therapy and regenerative medicine approaches. However, purification...

    Authors: Teoman Ozturk, Julien Mignot, Francesca Gattazzo, Marianne Gervais, Frédéric Relaix, Hélène Rouard and Nathalie Didier
    Citation: Stem Cell Research & Therapy 2024 15:179
  27. Bone marrow stromal cells (BMSCs) are highly heterogeneous, which may reflect their diverse biological functions, including tissue maintenance, haematopoietic support and immune control. The current understand...

    Authors: Andrew P. Stone, Emma Rand, Gabriel Thornes, Alasdair G. Kay, Amanda L. Barnes, Ian S. Hitchcock and Paul G. Genever
    Citation: Stem Cell Research & Therapy 2024 15:178
  28. Cartilage is a kind of avascular tissue, and it is difficult to repair itself when it is damaged. In this study, we investigated the regulation of chondrogenic differentiation and vascular formation in human j...

    Authors: Hua Liu, Huina Liu, Qiubo Yang and Zhipeng Fan
    Citation: Stem Cell Research & Therapy 2024 15:177
  29. The aim of this study is to systematically review randomized controlled clinical trials (RCTs) studying various types of regenerative medicine methods (such as platelet-rich plasma, stromal vascular fraction, ...

    Authors: Alireza Jafarzadeh, Arash Pour Mohammad, Haniyeh Keramati, Roya Zeinali, Mina Khosravi and Azadeh Goodarzi
    Citation: Stem Cell Research & Therapy 2024 15:176
  30. Endothelial cells (ECs) are widely used as donor cells in tissue engineering, organoid vascularization, and in vitro microvascular model development. ECs are invaluable tools for disease modeling and drug scre...

    Authors: Dan Deng, Yu Zhang, Bo Tang and Zhihui Zhang
    Citation: Stem Cell Research & Therapy 2024 15:175
  31. Chimeric antigen receptor (CAR)-T cell adoptive immunotherapy is a promising cancer treatment that uses genetically engineered T cells to attack tumors. However, this therapy can have some adverse effects. CAR...

    Authors: Farnaz Sani, Shabnam Shojaei, Seyed Amirhossein Tabatabaei, Mohammadhossein Khorraminejad-Shirazi, Mona Latifi, Mahsa Sani and Negar Azarpira
    Citation: Stem Cell Research & Therapy 2024 15:174
  32. Spinal cord injury (SCI) is a disease that causes permanent impairment of motor, sensory, and autonomic nervous system functions. Stem cell transplantation for neuron regeneration is a promising strategic trea...

    Authors: Jang-Woon Kim, Juryun Kim, Soon Min Lee, Yeri Alice Rim, Young Chul Sung, Yoojun Nam, Hyo-Jin Kim, Hyewon Kim, Se In Jung, Jooyoung Lim and Ji Hyeon Ju
    Citation: Stem Cell Research & Therapy 2024 15:173
  33. Development of hematopoietic stem and progenitor cells (HSPC) is a multi-staged complex process that conserved between zebrafish and mammals. Understanding the mechanism underlying HSPC development is a holy g...

    Authors: Min He, Xiaoli Li, Bingxiang Xu, Yinbo Lu, Jingyi Lai, Yiming Ling, Huakai Liu, Ziyang An, Wenqing Zhang and Feifei Li
    Citation: Stem Cell Research & Therapy 2024 15:172
  34. There is a significant demand for intermediate-scale bioreactors in academic and industrial institutions to produce cells for various applications in drug screening and/or cell therapy. However, the applicatio...

    Authors: Mania Ackermann, Fawaz Saleh, Shifaa M. Abdin, Anna Rafiei Hashtchin, Ingrid Gensch, Julia Golgath, Marco Carvalho Oliveira, Ariane H. H. Nguyen, Svenja Gaedcke, Arno Fenske, Mi-Sun Jang, Adan C. Jirmo, Markus Abeln, Gesine Hansen and Nico Lachmann
    Citation: Stem Cell Research & Therapy 2024 15:171
  35. With the development of the economy and the increasing prevalence of skin problems, cutaneous medical aesthetics are gaining more and more attention. Skin disorders like poor wound healing, aging, and pigmenta...

    Authors: Junyi Li, Ye Liu, Rui Zhang, Qianyu Yang, Wei Xiong, Yan He and Qingsong Ye
    Citation: Stem Cell Research & Therapy 2024 15:169
  36. Mechanical stimulation (MS) significantly increases the release of adenine and uracil nucleotides from bone marrow-derived mesenchymal stem cells (BM-MSCs) undergoing osteogenic differentiation. Released nucle...

    Authors: Catarina Bessa-Andrês, Rui Pinto-Cardoso, Karyna Tarasova, Ana Luísa Pereira-Gonçalves, Joana Maria Gaio-Ferreira-Castro, Liliana S. Carvalho, Maria Adelina Costa, Fátima Ferreirinha, Ana Canadas-Sousa, José Marinhas, Rolando Freitas, Rui Lemos, Adélio Vilaça, António Oliveira, Paulo Correia-de-Sá and José Bernardo Noronha-Matos
    Citation: Stem Cell Research & Therapy 2024 15:168
  37. Stem cell therapy is a promising alternative for inflammatory diseases and tissue injury treatment. Exogenous delivery of mesenchymal stem cells is associated with instant blood-mediated inflammatory reactions...

    Authors: Shobha Regmi, Shiva Pathak, Dinesh Chaudhary, Jong Oh Kim, Joo-Won Nam, Hyung-Sik Kim, Hu-Lin Jiang, Dongryeol Ryu, Jong-Hyuk Sung, Simmyung Yook and Jee-Heon Jeong
    Citation: Stem Cell Research & Therapy 2024 15:167
  38. Hypertrophic scarring results from myofibroblast differentiation and persistence during wound healing. Currently no effective treatment for hypertrophic scarring exists however, autologous fat grafting has bee...

    Authors: S. Higginbotham, V. L. Workman, A-V. Giblin, N. H. Green, D. W. Lambert and V. Hearnden
    Citation: Stem Cell Research & Therapy 2024 15:166
  39. Mesenchymal stem cells (MSCs) have emerged as living biodrugs for myocardial repair and regeneration. Recent randomized controlled trials (RCTs) have reported that MSC-based therapy is safe and effective in he...

    Authors: Ziyad T. Ahmed, Maha Saad Zain Al-Abeden, Mohamed Ghaith Al Abdin, Mohamad Ayham Muqresh, Ghazi I. Al Jowf, Lars M. T. Eijssen and Khawaja Husnain Haider
    Citation: Stem Cell Research & Therapy 2024 15:165
  40. Transplantation of CD34+ hematopoietic stem and progenitor cells (HSPC) into immunodeficient mice is an established method to generate humanized mice harbouring a human immune system. Different sources and method...

    Authors: Teja Celhar, Xinyi Li, Yunqian Zhao, Hui Chien Tay, Andrea Lee, Hui Hua Liew, Edwin Kunxiang Shepherdson, Ravisankar Rajarethinam, Yiping Fan, Anselm Mak, Jerry Kok Yen Chan, Amit Singhal and Takeshi Takahashi
    Citation: Stem Cell Research & Therapy 2024 15:164
  41. A rising population faces challenges with healing-impaired cutaneous wounds, often leading to physical disabilities. Adipose-derived stem cells (ASCs), specifically in the cell sheet format, have emerged as a ...

    Authors: Yueh-Chen Chen, Er-Yuan Chuang, Yuan-Kun Tu, Chia-Lang Hsu and Nai-Chen Cheng
    Citation: Stem Cell Research & Therapy 2024 15:163
  42. Autologous mesenchymal stem cells (MSCs) have emerged as a therapeutic option for many diseases. Hypertensive kidney disease (HKD) might impair MSCs’ reparative ability by altering the biomolecular properties,...

    Authors: Gurparneet Kaur Sohi, Naba Farooqui, Arjunmohan Mohan, Kamalnath Sankaran Rajagopalan, Li Xing, Xiang Y. Zhu, Kyra Jordan, James D. Krier, Ishran M. Saadiq, Hui Tang, LaTonya J. Hickson, Alfonso Eirin, Lilach O. Lerman and Sandra M. Herrmann
    Citation: Stem Cell Research & Therapy 2024 15:162
  43. Mesenchymal stem cell treatment (MST) has emerged as a new therapeutic strategy for Crohn’s perianal fistulas. It has been demonstrated that a fibrotic tract on MRI with a MAGNIFI-CD score ≤ 6 is the best pred...

    Authors: A. J. M. Pronk, K. J. Beek, M.E. Wildenberg, W. A. Bemelman, J. Stoker and C. J. Buskens
    Citation: Stem Cell Research & Therapy 2024 15:161
  44. Metabolic syndrome (MetS) is a significant epidemiological problem worldwide. It is a pre-morbid, chronic and low-grade inflammatory disorder that precedes many chronic diseases. Wharton’s jelly-derived mesenc...

    Authors: Alvin Man Lung Chan, Angela Min Hwei Ng, Mohd Heikal Mohd Yunus, Ruszymah Hj Idrus, Jia Xian Law, Muhammad Dain Yazid, Kok-Yong Chin, Mohd Rafizul Mohd Yusof, See Nguan Ng, Benson Koh and Yogeswaran Lokanathan
    Citation: Stem Cell Research & Therapy 2024 15:160
  45. Intra-articular injection of adipose-derived mesenchymal stromal cells (ASCs) and/or platelet-rich plasma (PRP) have been reported to independently and synergistically improve healing of osteochondral lesions ...

    Authors: Tomoya Iseki, Benjamin B. Rothrauff, Shinsuke Kihara, Kalon J. Overholt, Tarek Taha, Hang Lin, Peter G. Alexander and Rocky S. Tuan
    Citation: Stem Cell Research & Therapy 2024 15:159

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 7.1
    5-year Journal Impact Factor: 7.9
    Source Normalized Impact per Paper (SNIP): 1.277
    SCImago Journal Rank (SJR): 1.798

    Speed 2023
    Submission to first editorial decision (median days): 34
    Submission to acceptance (median days): 211

    Usage 2023
    Downloads: 3,320,811
    Altmetric mentions: 1,402